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556432 Aldrich

4-Ethynyl-α,α,α-trifluorotoluene

97%

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Properties

Related Categories Alkynyl, Building Blocks, Chemical Synthesis, Halogenated Hydrocarbons, Organic Building Blocks More...
InChI Key   XTKBMZQCDBHHKY-UHFFFAOYSA-N
assay   97%
refractive index   n20/D 1.4650(lit.)
bp   78-80 °C/2 mmHg(lit.)
density   1.043 g/mL at 25 °C(lit.)

Description

Packaging

5 g in glass bottle

Application

Used to synthesize self-assembled monolayers (SAMs).

General description

4-Ethynyl-α,α,α-trifluorotoluene reacts with ethanol to afford the corresponding α,β-alkynyl ester. 4-Ethynyl-α,α,α-trifluorotoluene plays the role of a functionalized alkyne in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction on BrPP thin films.

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Safety & Documentation

Safety Information

Symbol 
GHS02  GHS02
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 1993BE 3 / PGII
WGK Germany 
3
Flash Point(F) 
68 °F
Flash Point(C) 
20 °C
Protocols & Articles

Articles

New Aromatic Terminal Alkynes

The terminal alkyne functionality has a wide range of applications including most recently the synthesis of spiropyran substituted 2,3-dicyanopyrazines1 and (±)-asteriscanolide,2 as well as conversio...
Chemfiles Volume 3 Article 5
Keywords: Applications, Medicinal chemistry, Organic synthesis

Related Content

Alkynes and Acetylenic Building Blocks

Aldrich Chemistry lists over 600 alkyne building blocks, including a wide array of propargyl alcohols, acetylenic boron reagents, and halogenated substrates for cross-coupling. Additionally, many of ...
Keywords: Building blocks, Coupling reactions, Cross couplings

Peer-Reviewed Papers
15

References

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