Grubbs Catalyst, 2^nd Generation

Papers

1. The development of L2X2Ru=CHR olefin metathesis catalysts: an organometallic success story. T.M. Trnka, R.H. Grubbs Acc. Chem. Res. 34, 18, (2001)

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2. Grubbs, R. H. Tetrahedron 60, 7117, (2004)

3. Schrodi, Y.; Pederson, R. L. Aldrichimica Acta 40th ed.,, 45, (2007)

4. Ruthenium-based heterocyclic carbene-coordinated olefin metathesis catalysts. Vougioukalakis, G. C.; Grubbs, R. H. Chem. Rev. 110, 1746, (2010)

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5. Olefin Metathesis and Beyond A list of abbreviations can be found at the end of this article. Fürstner, A. Angew. Chem. Int. Ed. Engl. 39, 3012, (2000)

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6. Schuster, M.; Blechert, S. Angew. Chem. Int. Ed. Engl. 36th ed.,, 2036, (1997)

7. Ritter, T., et al. Organometallics 25th ed.,, 5740, (2006)

8. Org. Lett. 1, 751, (1999)

9. Synthesis and activity of a new generation of ruthenium-based olefin metathesis catalysts coordinated with 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene ligands. Scholl, M. Org. Lett. 1, 953, (1999)

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Synthesis of trisubstituted alkenes via olefin cross-metathesis. Chatterjee, A. K., Grubbs, R. H. Org. Lett. 1, 1751, (1999)

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Expanded scope in ethylene-alkyne cross-metathesis: coordinating heteroatom functionality at the propargylic position. J.A. Smulik, S.T. Diver Org. Lett. 2, 2271, (2000)

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Highly Efficient Ring-Opening Metathesis Polymerization (ROMP) Using New Ruthenium Catalysts Containing N-Heterocyclic Carbene Ligands C.B. is grateful to the National Science Foundation for a pre-doctoral fellowship. The authors thank Dr. Matthias Scholl for providing catalysts 4 a and 4 c. Bielawski, C. W.; Grubbs, R. H. Angew. Chem. Int. Ed. Engl. 39, 2903, (2000)

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Olefin-metathesis catalysts for the preparation of molecules and materials (Nobel Lecture). Grubbs, R. H. Angew. Chem. Int. Ed. Engl. 45, 3760, (2006)

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Unusual influence of substituents on ring-opening metathesis reactions. Wright, D. L.; Usher, L. J.; Estrella-Jiminez, M. Org. Lett. 3, 4275, (2001)

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Synthesis of trisubstituted alkenes via olefin cross-metathesis. Chatterjee, A. K., Grubbs, R. H. Org. Lett. 1, 1751, (1999)

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Scholl, M. Acc. Chem. Res. 1, 953, (1999)

Efficient large-scale synthesis of BILN 2061, a potent HCV protease inhibitor, by a convergent approach based on ring-closing metathesis. J. Org. Chem. 71, 7133, (2006)

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Tetrahedron 62, 9017, (2006)

Macrocyclic inhibitors of beta-secretase: functional activity in an animal model. J. Med. Chem. 49, 6147, (2006)

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