569747 Aldrich

Grubbs Catalyst, 2nd Generation

Synonym: (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, Benzylidene[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(tricyclohexylphosphine)ruthenium, [1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium


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Metathesis: Ruthenium-Based Metathesis Catalysts

Catalyst for ring-closing metathesis, cross metathesis and ROMP1 able to produce trisubstituted olefins via cross metathesis,8 and ring closes olefins with excellent functional group tolerance and selectivity.9

Grubbs 2nd Generation Catalyst

Generally more active compared to 1st generation catalysts and with a broader substrate scope, including sterically demanding or deactivated olefins such as 1,1-disubstituted olefins and α,β-unsaturated carbonyls.1,2,3,4,5,6,7

Other Notes



100, 500 mg in glass bottle

2 g in glass bottle

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US Patent No. 6,111,121 and 7,329,758 (and associated foreign equivalents of the foregoing) apply. Sale of this product conveys to the buyer a limited-use research license. For full details of this license please see sigma-aldrich.com/materialicense. For questions, please contact us at aldrich@sial.com or Materia at info@materia-inc.com.

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