Synonym: (S)-2,6-Diaminocaproic acid-4,4,5,5-d4 hydrochloride, Deuterated Lys, Deuterated lysine, SILAC Amino Acid
Linear Formula H2NCH2(CD2)2CH2CH(NH2)CO2H · HCl
Molecular Weight 186.67
MDL number MFCD01074061
|Related Categories||Alphabetical Listings, Amino Acids, Biomolecular Mass Spectrometry, I-L, Metabolic Labeling,|
|isotopic purity||98 atom % D|
|optical activity||[α]25/D +20.7°, c = 2 in 5 M HCl|
|mol wt||mol wt 186.59 by atom % calculation|
|mp||263-264 °C (dec.)(lit.)|
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Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) was developed to monitor the relative abundance of proteins by mass spectrometry1. This method works on the premise that cell treatment ...
Sven-Thorsten Liffers,1 Nurhan Ozlu,1,2 Dalila Bensaddek,1 Judith Steen,1,3 Hanno Steen1
ISOTEC® Stable Isotopes: Expanding the Boundaries of Quantitative Proteomics, 2008, 2–4
Keywords: Acetylations, Cancer, Cell culture, Chromatography, Derivatizations, Digestions, Growth factors, High performance liquid chromatography, Mass spectrometry, Methylations, Phosphorylations, Proteomics, Purification, Substitutions, Transcription
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