2-Iodoimidazole 97% | Sigma-Aldrich

Properties

Related Categories	Building Blocks, C3 to C8, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Imidazoles More...
assay	97%

Description

Packaging

1, 5 g in glass bottle

Application

Reactant involved in:
• Alkylation leading to alkyl derivatives with antibacterial activity¹
• Iodination of N-tritylimidazole²
• Photochemical intramolecular aromatic substitutions³
• Synthesis of cyclopentapyrazines using thermolysis⁴

Price and Availability

Related Papers

1. Creating an antibacterial with in vivo efficacy: synthesis and characterization of potent inhibitors of the bacterial cell division protein FtsZ with improved pharmaceutical properties D. J. Haydon, et al., J. Med. Chem. 53, 3927-3936, (2010)

Documents

Certificate of Analysis

Safety Information

Symbol	GHS07
Signal word	Warning
Hazard statements	H319
Precautionary statements	P305 + P351 + P338
Personal Protective Equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany	3

Technical information & documentation associated with this product is available in the Safety & Documentation tab.

Articles

Halogenated Aryl and Heteroaryl Substrates

The use of halogenated aryl and heteroaryl compounds as substrates in various coupling protocols (i.e., Suzuki, Stille, Sonogashira) and nucleophilic substitution is commonplace in communications amo...
Aldrich ChemFiles 2006, 6.6, 11.
Keywords: Nucleophilic substitutions, Substitutions

Papers

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1. Creating an antibacterial with in vivo efficacy: synthesis and characterization of potent inhibitors of the bacterial cell division protein FtsZ with improved pharmaceutical properties D. J. Haydon, et al., J. Med. Chem. 53, 3927-3936, (2010)

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2. Palladium-catalyzed intramolecular arylation of N-benzyl-2-iodoimidazoles: a facile and rapid access to 5H-imidazo[2,1-a]isoindoles R. M. de Figueiredo, et al., Synthesis 4, 529-540, (2007)

3. Photochemical intramolecular aromatic substitutions of the imidazol-2-yl radical are superior to those mediated by Bu3SnH M. A. Clyne and F. Aldabbagh, Org. Biomol. Chem. 4, 268-277, (2006)

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4. Intra- and intermolecular trapping of cyclopentapyrazine carbenes derived from 1,2-dialkynylimidazoles A. K. Nadipuram and S. M. Kerwin, Tetrahedron Lett. 47, 353-356, (2006)

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2-Iodoimidazole

97%