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  • 698393 - 1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene(1,5-cyclooctadiene)rhodium(I) trifluoromethanesulfonate

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698393 Aldrich

1,2-Bis[(2R,5R)-2,5-diethylphospholano]benzene(1,5-cyclooctadiene)rhodium(I) trifluoromethanesulfonate

Synonym: (R,R)-Et-DUPHOS-Rh

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Description

Packaging

50, 250 mg in glass insert

Legal Information

Sold in collaboration with Kanata Chemical Technologies Inc. for research purposes only. These compounds were made and sold under license from E.I. du Pont de Nemours and Company, which license does not include the right to use the compounds in producing products for sale in the pharmaceutical field.

Application

DuPhos and BPE Ligands: Highly Efficient Privileged Ligands

Catalyst for:
• Stereoselective synthesis of δ-amino acid derivatives via asymmetric hydrogenation of acetylaminopentenoic acid derivatives
• Stereoselective synthesis of manzacidins A and C via stereoselective hydrogenation
• Stereoselective synthesis of tetracyclic core of manzamine A via Rh-catalyzed asymmetric hydrogenation, diastereoselective Diels-Alder reaction, Eschenmoser-Tanabe fragmentation, Chang′s amide formation, and Hofmann rearrangement
• Asymmetric preparation of chiral Cbz-aminodifluorobutyric acid Me ester and its analogs
• Biphasic catalytic hydrogenations in ionic liquids with addition of water as a second solvent
• Preparation of cyclobutane-containing amino acids via asymmetric hydrogenations of cyclobutyl enamides
• Asymmetric preparation of both enantiomers of (dimethoxycoumaryl)alanine as suitable fluorescent peptide labels

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

DuPhos and BPE Phospholane Ligands and Complexes

In the early 1990s, Burk and coworkers developed new electron-rich C2 symmetric bis(phospholane) ligands. The modular nature of these ligands allowed for variation of both phosphane substituent and b...
William Sommer and Daniel Weibel
Aldrich ChemFiles 2008, 8.2, 34.
Keywords: Aminations, Applications, Asymmetric catalysis, Asymmetric synthesis, Building blocks, Catalysis, Chemfiles, Crotylborations, Hydrogenations, Ligands, Reductions, Reductive aminations

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