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701602 Aldrich

[1,1′-Bis(di-tert-butylphosphino)ferrocene]dichloropalladium(II) Green Alternative

98%

Synonym: PdCl2(dtbpf)

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Properties

Related Categories 12 Principles Aligned Products, Catalysis, Catalysis and Inorganic Chemistry, Chemical Synthesis, Development Quantities for Research,
InChI Key   JQZFOBWXNREQLO-UHFFFAOYSA-L
assay   98%
greener alternative product characteristics   Catalysis
Learn more about the Principles of Green Chemistry.
mp   203-208 °C
storage temp.   −20°C

Description

Packaging

1, 5, 50 g in glass bottle

250 mg in glass bottle

Application

Application Guide for Palladium Catalyzed Cross-Coupling Reactions

[1,1′-Bis(di-tert-butylphosphino)ferrocene]dichloropalladium(II) (PdCl2(dtbpf)) may be used as catalyst in the Suzuki cross-coupling reaction of various aromatic and heteroaromatic halides with methyliminodiacetic acid derivatives (MIDA boronates) at room temperature (in the absence of organic solvent). It may be employed as catalyst for the synthesis of chalcones, via cross-coupling reactions.

[1,1′-Bis(di-tert-butylphosphino)ferrocene]dichloropalladium(II) was used in the preparation of [PdCl2(bisphosphinometallocene)] complexes. These complexes are reported to be the catalyst precursors for the Buchwald-Hartwig reaction.
It is also employed as catalyst for greener Suzuki cross-coupling in TPGS-750-M.

On the Way Towards Greener Transition-Metal-Catalyzed Processes as Quantified by E Factors

General description

Sigma Life Science is committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for energy efficiency. Find details here.

[1,1′-Bis(di-tert-butylphosphino)ferrocene]dichloropalladium(II) (PdCl2(dtbpf)) participates as catalyst in Suzuki and Heck reactions. It is a preformed catalyst synthesized by a group of researchers at Johnson Matthey′s Catalysis and Chiral Technologies. It is an active catalyst for various Pd catalyzed cross-coupling reactions.

[1,1′-Bis(di-tert-butylphosphino)ferrocene]dichloropalladium(II) is an air-stable, highly active and versatile catalyst. It is an efficient catalyst for cross-coupling reactions. It participates as catalyst in various coupling reactions of the fine chemicals and pharmaceutical chemicals. It is commonly employed as homogeneous catalyst in the Suzuki reactions.

Price and Availability


Cross-Coupling Guide
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Amination of Aryl Halides

The Buchwald-Hartwig amination reaction, or the coupling between an aryl halide and an amine, is extremely important in various areas of both academic and industrial research. The amination of aryl c...
Josephine Nakhla
Aldrich ChemFiles 2009, 9.2, 11.
Keywords: Aminations, Buchwald-Hartwig amination, Catalysis, Chemfiles, Ligands

BRIDP Catalysts

Researchers at Takasago developed two phosphine-based ligands for the Buchwald-Hartwig amination reaction with successful results for the cross-coupling of a wide array of amines and aryl halides. Th...
Josephine Nakhla
Aldrich ChemFiles 2009, 9.2, 11.
Keywords: Aminations, Arylations, Buchwald-Hartwig amination, Catalysis, Chemfiles, Cross couplings, Electronics, Ligands

Ferrocenyl Based Ligands and Catalysts

Hartwig and co-workers have reported the use of the electron-rich and bulky ligand 1,1’-bis(di-tert-butylphosphino)ferrocene for the amination of aryl halides and for the first amination of aryl tosy...
Josephine Nakhla
Aldrich ChemFiles 2009, 9.2, 11.
Keywords: Aminations, Catalysis, Chemfiles, Eliminations, Ligands, Oxidative additions, Reductive eliminations

Heck Reaction

The Heck reaction is the palladium catalyzed cross-coupling reaction between alkenes, and aryl or vinyl halides (or triflates) to afford substituted alkenes.1,2 It is a useful carbon–carbon bond form...
Keywords: Asymmetric synthesis, Cancer, Catalysis, Coupling reactions, Cross couplings, Heck Reaction, Herbicides, Ligands, Organic synthesis, Solvents

Protocols

Procedures for Transition-Metal-Catalyzed Cross-Coupling Reactions

TPGS-750-M, DL-α-Tocopherol methoxypolyethylene glycol succinate, is a designer surfactant composed of a lipophilic α-tocopherol moiety and a hydrophilic PEG-750-M chain, joined by an inexpensive suc...
Keywords: Aminations, Buchwald-Hartwig amination, Catalysis, Chromatography, Coupling reactions, Cross couplings, Environmental, Evaporation, Flash chromatography, Heck Reaction, Ligands, Metathesis, Olefin metathesis

Suzuki Cross-Coupling in Lipshutz Surfactant

Please consult the Safety Data Sheet for information regarding hazards and safe handling practices.
Keywords: Chromatography, Evaporation, Flash chromatography

Suzuki Kit

Please consult the Safety Data Sheet for information regarding hazards and safe handling practices.
Keywords: Chromatography, Column chromatography, Gas chromatography, High performance liquid chromatography, Thin layer chromatography

Suzuki-Miyaura Reaction in Water at Room Temperature using TPGS-750-M

TPGS-750-M, DL-α-Tocopherol methoxypolyethylene glycol succinate, is a designer surfactant composed of a lipophilic α-tocopherol moiety and a hydrophilic PEG-750-M chain, joined by an inexpensive suc...
Keywords: Catalysis, Chromatography, Coupling reactions, Cross couplings, Environmental, Evaporation, Flash chromatography

Related Content

Application Guide for Palladium Catalyzed Cross-Coupling Reactions

Palladium catalyzed cross-coupling reactions have revolutionized the way in which molecules are constructed. From the fields of organic synthesis and medicinal chemistry, to materials science and pol...
Keywords: Catalysis, Coupling reactions, Cross couplings, Materials Science, Medicinal chemistry, Organic synthesis, Polymer science, Type, transformation

Peer-Reviewed Papers
15

References

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