Lactide and Glycolide Polymers,
|feed ratio||lactide:glycolide 50:50|
|mol wt||Mw 7,000-17,000|
|degradation timeframe||<3 months|
|viscosity||0.16-0.24 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde)(size 0c glass capillary viscometer)|
|transition temp||Tg 42-46 °C|
5 g in glass bottle
Product of Evonik
RESOMER is a registered trademark of Evonik Rohm GmbH
Biocompatible, biodegradable polymer.
Controlled release of bioactive agents, sutures and bioabsorbable implantable devices.
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Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been w...
Anna Musyanovych and Katharina Landfester
Material Matters 2012 v7, n3
Keywords: Adhesion, Antitumor agents, Biomaterials, Central Nervous System, Degradations, Deposition, Diffusion, Evaporation, Growth factors, Melting, Microscopy, Precipitation, Purification, Reductions, Scanning electron microscopy
The ability for synthetic polymers to degrade in a controlled manner was developed for environmental reasons in the late 1960s. Interest in utilizing biodegradable polymers for biomedical application...
Keywords: Cancer, Degradations, Diagnostic, Diffusion, Environmental, Evaporation, Hormones, PEGylations, Polymerization reactions, Reductions, Ring-opening polymerization, Separation
Isoniazid loaded core shell nanoparticles derived from PLGA-PEG-PLGA tri-block copolymers: in vitro and in vivo drug release. Gajendiran M, Gopi V, Elangovan V, et al. Colloids Surf. B Biointerfaces 104, 107-15, (2013)
Triclosan-coated sutures reduce the incidence of wound infections and the costs after colorectal surgery: a randomized controlled trial. Nakamura T, Kashimura N, Noji T, et al. Surgery 153(4), 576-83, (2013)
A single-surgeon randomized trial comparing three meshes in lichtenstein hernia repair: 2- and 5-year outcome of recurrences and chronic pain. Paajanen H, Rönkä K, and Laurema A Int. J. Surg. 11(1), 81-4, (2013)
A biomechanical study of laparoscopic 4S-modified Roeder and Weston knot strength in 3-0 polyglactin 910 and 3-0 polydioxanone. Fugazzi RW, Fransson BA, Curran KM, et al. Vet. Surg. 42(2), 198-204, (2013)
Effects of suture choice on biomechanics and physeal status after bioenhanced anterior cruciate ligament repair in skeletally immature patients: a large-animal study. Vavken P, Proffen B, Peterson C, et al. Arthroscopy 29(1), 122-32, (2013)
Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis. Getts DR, Martin AJ, McCarthy DP, et al. Nat. Biotechnol. 30(12), 1217-24, (2012)
Tracking injectable microspheres in dynamic tissues with encapsulated superparamagnetic iron oxide nanoparticles. Franklin-Ford T, Shah N, Leiferman E, et al. Macromol. Biosci. 12(12), 1615-21, (2012)
Development of novel cationic chitosan-and anionic alginate-coated poly(D,L-lactide-co-glycolide) nanoparticles for controlled release and light protection of resveratrol. Sanna V, Roggio AM, Siliani S, et al. Int. J. Nanomedicine 7, 5501-16, (2012)
Clinical and radiological evaluation of human osseous defects (mandibular grade ii furcation involvement) treated with bioresorbable membrane: vicryl mesh. Balusubramanya KV, Ramya R, and Govindaraj SJ J. Contemp. Dent. Pract. 13(6), 806-11, (2012)
Induction of long-lasting protective immunity against Toxoplasma gondii in BALB/c mice by recombinant surface antigen 1 protein encapsulated in poly (lactide-co-glycolide) microparticles. Chuang SC, Ko JC, Chen CP, et al. Parasit. Vectors 6, 34, (2013)
Clinical and histological comparison of polyglycolic acid suture with black silk suture after minor oral surgical procedure. Balamurugan R, Mohamed M, Pandey V, et al. J. Contemp. Dent. Pract. 13(4), 521-7, (2012)
Structure Index 1, 501:D:4
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