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742678 Aldrich

(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol

for Copper-free Click Chemistry

Synonym: (1α,8α,9β)-Bicyclo[6.1.0]non-4-yne-9-methanol, endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne, BCN-OH

  • CAS Number 1263166-90-0

  • Empirical Formula (Hill Notation) C10H14O

  • Molecular Weight 150.22

  •  Beilstein Registry Number 21037713

  •  MDL number MFCD26142970

  •  PubChem Substance ID 329765586

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Properties

Related Categories Chemical Biology, Chemical Synthesis, Conjugation Chemistry: Azides, Alkynes and Other Reagents, Copper-Free Click Chemistry, Cyclooctynes for Cu(I)-free Cycloadditions More...
InChI Key   NSVXZMGWYBICRW-ILWJIGKKSA-N
composition   carbon content, 79.96%
  hydrogen content, 9.39%
storage temp.   −20°C

Description

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Application

Alcohol functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This strained cyclooctyne will react with azide functionalized compounds or biomolecules without the need for a copper catalyst to result in a stable triazole linkage.

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Cross-Coupling Guide

The Future of Bioimaging
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Copper-Free Click Chemistry

Click chemistry involves the rapid generation of compounds by joining small units together via heteroatom links (C-X-C). The main objective of click chemistry is to develop a set of powerful, selecti...
Keywords: 1,3-Dipolar cycloaddition, Catalysis, Chemical biology, Click chemistry, Combinatorial synthesis, Cycloadditions, Drug discovery, Materials Science, Medicinal chemistry, Pharmaceutical, Positron Emission Tomography

Peer-Reviewed Papers
15

References

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