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804223 Aldrich

3-oxo-C12-aniline

Synonym: 3-oxo-N-phenyl-Dodecanamide, LasR inhibitor, non-hydrolysable head group

  • CAS Number 1186509-19-2

  • Empirical Formula (Hill Notation) C18H27NO2

  • Molecular Weight 289.41

  •  PubChem Substance ID 329768853

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Properties

Related Categories Chemical Biology, Chemical Synthesis, Probes and Sensors, Quorum Sensors
InChI Key   GYOZLHQAMICVMN-UHFFFAOYSA-N
storage temp.   −20°C

Description

Packaging

10 mg in glass bottle

Application

This analog mimics the native 3-oxo-C12 AHL signal utilized by Pseudomonas aeruginosa for quorum sensing, yet contains a non-hydrolysable aniline head group. 3-oxo-C12-aniline is a strong inhibitor of the LasR receptor in P. aeruginosa.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Helen Blackwell Group - Professor Product Portal

From our library of Articles, Sigma-Aldrich presents Helen Blackwell Group - Professor Product Portal
Keywords: Antimicrobials, Biological processes, Chemical biology, Gene expression, Ligands, Microbiology

Quorum Sensing Modulators

Quorum sensing is a chemical communication mechanism used by many common bacteria to initiate group behaviors. It plays an important role in the establishment of infection by pathogens and in mediati...
Keywords: Ligands

Peer-Reviewed Papers
15

References

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