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804231 Aldrich

2-bromo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-Benzeneacetamide

Synonym: AbaR, QscR inhibitor

  • CAS Number 942296-18-6

  • Empirical Formula (Hill Notation) C12H12BrNO3

  • Molecular Weight 298.13

  •  PubChem Substance ID 329768854

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Properties

Related Categories Chemical Biology, Chemical Synthesis, Probes and Sensors, Quorum Sensors
InChI Key   MMJSTOMMZPSKSQ-JTQLQIEISA-N
storage temp.   −20°C

Description

Packaging

10 mg in glass bottle

Application

The following AHL is a phenylacetanoyl L-homoserine lactone (PHL), a class of compounds found to strongly modulate many LuxR-type receptors. It is an active inhibitor of the putative LuxR-type receptor in Acinetobacter baumannii – AbaR and the quorum-sensing repressor in P. aeruginosa – QscR.

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Helen Blackwell Group - Professor Product Portal

From our library of Articles, Sigma-Aldrich presents Helen Blackwell Group - Professor Product Portal
Keywords: Antimicrobials, Biological processes, Chemical biology, Gene expression, Ligands, Microbiology

Quorum Sensing Modulators

Quorum sensing is a chemical communication mechanism used by many common bacteria to initiate group behaviors. It plays an important role in the establishment of infection by pathogens and in mediati...
Keywords: Ligands

Peer-Reviewed Papers
15

References

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