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804258 Aldrich

N-(3-(4-bromophenyl)-propanoyl)-L-homoserine lactone

Synonym: 4-bromo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-benzenepropanamide, LasR and TraR inhibitor, LuxR

  • CAS Number 959613-39-9

  • Empirical Formula (Hill Notation) C13H14BrNO3

  • Molecular Weight 312.16

  •  PubChem Substance ID 329768855

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Properties

Related Categories Chemical Biology, Chemical Synthesis, Probes and Sensors, Quorum Sensors
InChI Key   SGDZSJUYCLTPRG-NSHDSACASA-N
storage temp.   −20°C

Description

Packaging

10 mg in glass bottle

Application

AHL analog is a strong, broad-spectrum inhibitor of numerous LuxR-type receptors (e.g.: LuxR from Vibrio fischeri, LasR from P. aeruginosa, and TraR from Agrobacterium tumefaciens). This compound represents a good choice for initial testing of LuxR-type receptor inhibition.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Helen Blackwell Group - Professor Product Portal

From our library of Articles, Sigma-Aldrich presents Helen Blackwell Group - Professor Product Portal
Keywords: Antimicrobials, Biological processes, Chemical biology, Gene expression, Ligands, Microbiology

Quorum Sensing Modulators

Quorum sensing is a chemical communication mechanism used by many common bacteria to initiate group behaviors. It plays an important role in the establishment of infection by pathogens and in mediati...
Keywords: Ligands

Peer-Reviewed Papers
15

References

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