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804339 Aldrich

4-iodo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-Benzeneacetamide

Synonym: AbaR inhibitor, TraR

  • CAS Number 942296-25-5

  • Empirical Formula (Hill Notation) C12H12INO3

  • Molecular Weight 345.13

  •  PubChem Substance ID 329768862

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Properties

Related Categories Chemical Biology, Chemical Synthesis, Probes and Sensors, Quorum Sensors
InChI Key   IMJUHEKUNKCNGB-JTQLQIEISA-N
storage temp.   −20°C

Description

Packaging

10 mg in glass bottle

Application

PHL is a strong inhibitor of several LuxR-type receptors, including LuxR from V. fischeri, TraR from A. tumefaciens, the putative LuxR-type receptor from A. baumannii – AbaR, and RhlR from P. aeruginosa. This compound represents a good choice for initial testing of LuxR-type receptor inhibition.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Helen Blackwell Group - Professor Product Portal

From our library of Articles, Sigma-Aldrich presents Helen Blackwell Group - Professor Product Portal
Keywords: Antimicrobials, Biological processes, Chemical biology, Gene expression, Ligands, Microbiology

Quorum Sensing Modulators

Quorum sensing is a chemical communication mechanism used by many common bacteria to initiate group behaviors. It plays an important role in the establishment of infection by pathogens and in mediati...
Keywords: Ligands

Peer-Reviewed Papers
15

References

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