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81300 Aldrich

Poly(ethylene glycol)

average Mn 20,000

Synonym: PEG

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Properties

Related Categories Essential Chemicals, Materials Science, PEG and Oligo Ethylene Glycol, Poly(ethylene glycol), Poly(ethylene glycol) (PEG) and PEG Solutions,
vapor density   >1 (vs air)
vapor pressure   <0.01 mmHg ( 20 °C)
form   flakes
autoignition temp.   581 °F
mol wt   average Mn 20,000
mp   63-66 °C
Ω-end   OH
α-end   OH

Description

Packaging

1 kg in poly bottle

5 kg in glass bottle

Application

PEG has been used to modify therapeutic proteins and peptides to increase their solubility and lower their toxicity.

Photopolymerized PEG hydrogels have emerging applications in the fabrication of bioactive and immunoisolating barriers for encapsulation of cells.

General description

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks PEG can have high water content, forming “hydrogels”. Hydrogel formation can be initiated by either crosslinking PEG by ionizing radiation or by covalent crosslinking of PEG macromers with reactive chain ends. PEG is a suitable material for biological applications because it does not trigger an immune response.

Other Notes

Molecular weight: Mn 16,000-24,000

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
Protocols & Articles

Articles

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. For decades, research in polymeric biomateria...
Keywords: Absorption, Angiogenesis, Biomaterials, Catalysis, Cell culture, Degradations, Eliminations, Growth factors, Infrared spectroscopy, Ligands, Michael Addition, Polymerization reactions, Ring-opening polymerization

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions Technical Article

1,2Malar A. Azagarsamy, 1Navakanth R. Gandavarapu, 1,2Kristi S. Anseth* 1Department of Chemical and Biological Engineering and 2the Howard Hughes Medical Institute, University of Colorado at Boulder,...
Keywords: Addition reactions, Adhesion, Biomaterials, Catalysis, Cell culture, Cell signaling, Chemical reactions, Click chemistry, Cycloadditions, Degradations, Growth factors, Huisgen Cycloaddition, Ligands, Michael Addition, Peptide synthesis, Polymerization reactions, Step-growth polymerization

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a three-dimensional (3D) fashion is a challenging requireme...
1,2Malar A. Azagarsamy, 1Navakanth R. Gandavarapu, 1,2Kristi S. Anseth*
Material Matters, 2012 v7, n3
Keywords: Addition reactions, Adhesion, Applications, Biomaterials, Catalysis, Cell culture, Cell signaling, Chemical reactions, Click chemistry, Cycloadditions, Degradations, Growth factors, Huisgen Cycloaddition, Ligands, Methods, Michael Addition, Peptide synthesis, Polymerization reactions, Step-growth polymerization, Tools, Type

Peer-Reviewed Papers
15

References

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