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81381 Aldrich

Mowiol® 4-88

Mw ~31,000

Synonym: Poly(vinyl alcohol)

Purchase

Properties

Related Categories Hydrophilic Polymers, Materials Science, Poly(vinyl alcohol) (PVA), Poly(vinyl alcohol) (PVA) and Copolymers, Polymer Science,
mol wt   Mw ~31,000
extent of labeling   86.7-88.7 mol% hydrolysis
  ~630 polymerization
impurities   10.0-11.6% residual content of acetyl
ign. residue   ≤0.5%
viscosity   3.5-4.5 mPa.s, 4 % in H2O(20 °C)
ester number   130‑150

Description

Packaging

1 kg in poly bottle

50, 250 g in poly bottle

Application

Mowiol® is used as an embedding medium for preserving stained cell dishes in the study of siRNA array production of HeLa cells. Mowiol® is also reported to be used as a mounting medium in:
• design of TSAR and its applications
• detection of the secreted and cytoplasmic fractions of IpaB, IpaC and IpaD by lysozyme permeabilization
• fluorescence recovery after photobleaching (FRAP).

Mowiol® may be used as a coating for sensors based on piezoelectric quartz crystals.1 Another probable use of Mowiol® is during the study of super fluorescence imaging of biocompatible carbon dots.2

General description

Mowiol® is a water soluble hydrocolloid mucoadhesive based on poly (vinyl alcohol). Mowiol® at pH 8.5 has a couple of advantages over other mounting media:
• its a liquid when the sample is mounted and solidifies after several hours, forming a permanent bond between the coverslip and slide
• fluorescence is stable when held in dark and at 4oC.

Legal Information

Mowiol is a registered trademark of Kuraray Europe GmbH

Price and Availability


Custom Polymer Synthesis

Additional Products to Explore

Poly(ethylene glycol)

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Poly(vinyl acetate)

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Polyvinylpyrrolidone

average mol wt 40,000

Sodium chloride

BioXtra, ≥99.5% (AT)

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Safety & Documentation

Safety Information

WGK Germany 
1
RTECS 
TR8100000

Documents

Certificate of Analysis

Protocols & Articles

Articles

Determination of Water Content in Polyvinyl alcohol Using Karl Fischer Titration

The sample examined by us was available in large particles and we were not able to make it dissolve. The addition of trichlormethane, xylene, formamide, n-methylpyrrolidone, butyrolactone and even th...
Keywords: Titrations

Peer-Reviewed Papers

References

Set your institution to view full text papers.

1. An electronic nose based on coated piezoelectric quartz crystals to certify ewes' cheese and to discriminate between cheese varieties. Paris VF, et al. Sensors 12(2), 1422-1436, (2012)

2. Super-resolution fluorescence imaging of biocompatible carbon dots. Leménager G, et al. Nanoscale 6, 8614-8623, (2014)

RNA interference and single particle tracking analysis of hepatitis C virus endocytosis. Coller KE PLoS Pathog. 5(12), e1000702, (2009)

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Comparison study of ferrofluid and powder iron oxide nanoparticle permeability across the blood-brain barrier. Hoff D, Sheikh L, Bhattacharya S, et al. Int. J. Nanomedicine 8, 703-10, (2013)

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Evaluation of a novel chitosan polymer-based adsorbent for the removal of chromium (III) in aqueous solutions. Zuo X and Balasubramanian R Carbohydr. Polym. 92(2), 2181-6, (2013)

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Cryogelation of molecularly imprinted nanoparticles: a macroporous structure as affinity chromatography column for removal of β-blockers from complex samples. Hajizadeh S, Xu C, Kirsebom H, et al. J. Chromatogr. A 1274, 6-12, (2013)

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Fabrication of mussel-inspired highly adhesive honeycomb films containing catechol groups and their applications for substrate-independent porous templates. Saito Y, Kawano T, Shimomura M, et al. Macromol. Rapid Commun. 34(8), 630-4, (2013)

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Properties of electrospun pollock gelatin/poly(vinyl alcohol) and pollock gelatin/poly(lactic acid) fibers. Chiou BS, Jafri H, Avena-Bustillos R, et al. Int. J. Biol. Macromol. 55, 214-20, (2013)

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Sprague-Dawley rats bearing McA-RH7777 cells for study of hepatoma and transarterial chemoembolization. Cho HR, Choi JW, Kim HC, et al. Anticancer Res. 33(1), 223-30, (2013)

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A practical guide for diagnosis and treatment of arteriovenous malformations in the oral and maxillofacial region. Su LX, Fan XD, Zheng JW, et al. Chin. J. Dent. Res. 17(2), 85-9, (2014)

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Comprehensive therapy for hemangioma presenting with Kasabach-Merritt syndrome in the maxillofacial region. Su L, Wang D, and Fan X J. Oral Maxillofac. Surg. 73(1), 92-8, (2015)

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Quantification of the effect of Lipo-PGE1 on angiogenesis. Eo S, Kwon C, Lee H, et al. J. Plast. Reconstr. Aesthet. Surg. 68(1), 104-12, (2015)

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Enrichment of reticulocytes from whole blood using aqueous multiphase systems of polymers. Kumar AA, Lim C, Moreno Y, et al. Am. J. Hematol. 90(1), 31-6, (2015)

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Development of novel nanoparticle for bone cancer. Patricio BF, Albernaz Mde S, Sarcinelli MA, et al. J. Biomed. Nanotechnol. 10(7), 1242-8, (2014)

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Use of a novel polyvinyl alcohol membrane as a pericardial substitute reduces adhesion formation and inflammatory response after cardiac reoperation. de Oliveira PP, Bavaresco VP, Silveira-Filho LM, et al. J. Thorac. Cardiovasc. Surg. 147(4), 1405-10, (2014)

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Bronchial artery embolization to control hemoptysis: comparison of N-butyl-2-cyanoacrylate and polyvinyl alcohol particles. Woo S, Yoon CJ, Chung JW, et al. Radiology 269(2), 594-602, (2013)

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Rosiglitazone-loaded nanospheres for modulating macrophage-specific inflammation in obesity. Di Mascolo D, J Lyon C, Aryal S, et al. J. Control. Release 170(3), 460-8, (2013)

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[Delta-sleep inducing peptide entrapment and release from polymer hydrogels based on modified polyvinyl alcohol in vitro]. Sukhanova TV, Artiukhov AA, Prudchenko IA, et al. Biomed. Khim. 59(1), 65-75, (2013)

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Rapid and efficient generation of neurons from human pluripotent stem cells in a multititre plate format. Zhang M, Schöler HR, and Greber B J. Vis. Exp. (73), e4335, (2013)

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Treatment of severe advanced emphysema with volume reduction using lung sealant: a case report of 2 patients. Falkenstern-Ge RF, Ingerl H, and Kohlhaeufl M J. Bronchology Interv. Pulmonol. 20(1), 58-62, (2013)

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Alkali recovery using PVA/SiO2 cation exchange membranes with different -COOH contents. Hao J, Gong M, Wu Y, et al. J. Hazard. Mater. 244-245, 348-56, (2013)

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Pd-modified Au on carbon as an effective and durable catalyst for the direct oxidation of HMF to 2,5-furandicarboxylic acid. Villa A, Schiavoni M, Campisi S, et al. ChemSusChem 6(4), 609-12, (2013)

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Soy proteins as environmentally friendly sizing agents to replace poly(vinyl alcohol). Chen L, Reddy N, and Yang Y Environ. Sci. Pollut. Res. Int. 20(9), 6085-95, (2013)

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Scalable method to produce biodegradable nanoparticles that rapidly penetrate human mucus. Xu Q, Boylan NJ, Cai S, et al. J. Control. Release 170(2), 279-86, (2013)

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Interpenetrating polymer network of locust bean gum-poly (vinyl alcohol) for controlled release drug delivery. Kaity S, Isaac J, and Ghosh A Carbohydr. Polym. 94(1), 456-67, (2013)

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Biocompatible nanofibers based on extremophilic bacterial polysaccharide, Mauran from Halomonas maura. Raveendran S, Dhandayuthapani B, Nagaoka Y, et al. Carbohydr. Polym. 92(2), 1225-33, (2013)

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Fast and continuous preparation of high polymerization degree cellulose nanofibrils and their three-dimensional macroporous scaffold fabrication. Song J, Tang A, Liu T, et al. Nanoscale 5(6), 2482-90, (2013)

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Improving wet and dry strength properties of recycled old corrugated carton (OCC) pulp using various polymers. Hamzeh Y, Sabbaghi S, Ashori A, et al. Carbohydr. Polym. 94(1), 577-83, (2013)

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Starch/polyvinyl alcohol blended materials used as solid carbon source for tertiary denitrification of secondary effluent. Li P, Zuo J, Xing W, et al. J. Environ. Sci. (China) 25(10), 1972-9, (2013)

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Evaluation of transport parameters for PVC based polyvinyl alcohol Ce(IV) phosphate composite membrane. Khan MM, Rafiuddin, and Inamuddin Mater. Sci. Eng. C. Mater. Biol. Appl. 33(4), 2360-6, (2013)

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Detecting phase separation of freeze-dried binary amorphous systems using pair-wise distribution function and multivariate data analysis. Chieng N, Trnka H, Boetker J, et al. Int. J. Pharm. 454(1), 167-73, (2013)

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A carbon nanotube-infused polysulfone membrane with polyvinyl alcohol layer for treating oil-containing waste water. Maphutha S, Moothi K, Meyyappan M, et al. Sci. Rep. 3, 1509, (2013)

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New surface-enhanced Raman scattering platforms: composite calcium carbonate microspheres coated with astralen and silver nanoparticles. Stetciura IY, Markin AV, Ponomarev AN, et al. Langmuir 29(12), 4140-7, (2013)

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Ternary PVA nanocomposites containing cellulose nanocrystals from different sources and silver particles: part II. Fortunati E, Luzi F, Puglia D, et al. Carbohydr. Polym. 97(2), 837-48, (2013)

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Influence of storage temperature and moisture on the performance of microsphere/hydrogel composites. Wang Y and Burgess DJ Int. J. Pharm. 454(1), 310-5, (2013)

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Binary PVA bio-nanocomposites containing cellulose nanocrystals extracted from different natural sources: part I. Fortunati E, Puglia D, Luzi F, et al. Carbohydr. Polym. 97(2), 825-36, (2013)

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Significant increases in potato Starch-Synthase and Starch-Branching-Enzyme activities by dilution with buffer containing dithiothreitol and polyvinyl alcohol 50 K. Mukerjea R, Gray AN, and Robyt JF Carbohydr. Res. 367, 25-8, (2013)

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Covalent incorporation of non-chemically modified gelatin into degradable PVA-tyramine hydrogels. Lim KS, Alves MH, Poole-Warren LA, et al. Biomaterials 34(29), 7097-105, (2013)

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Facile fabrication of AgNPs/(PVA/PEI) nanofibers: high electrochemical efficiency and durability for biosensors. Zhu H, Du M, Zhang M, et al. Biosens. Bioelectron. 49, 210-5, (2013)

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Comparison of polyvinyl alcohol coated nasal packing with non-absorbable nasal packing. Seol JH, Kim JM, Kim SS, et al. Rhinology 51(2), 137-42, (2013)

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Bi-layer composite dressing of gelatin nanofibrous mat and poly vinyl alcohol hydrogel for drug delivery and wound healing application: in-vitro and in-vivo studies. Jaiswal M, Gupta A, Agrawal AK, et al. J. Biomed. Nanotechnol. 9(9), 1495-508, (2013)

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Electrospun curcumin-loaded fibers with potential biomedical applications. Sun XZ, Williams GR, Hou XX, et al. Carbohydr. Polym. 94(1), 147-53, (2013)

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Poly(vinyl alcohol)/sodium alginate/layered silicate based nanofibrous mats for bacterial inhibition. Li W, Li X, Chen Y, et al. Carbohydr. Polym. 92(2), 2232-8, (2013)

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Development of noncytotoxic PLGA nanoparticles to improve the effect of a new inhibitor of p53-MDM2 interaction. Paiva AM, Pinto RA, Teixeira M, et al. Int. J. Pharm. 454(1), 394-402, (2013)

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Toxicity of surface-modified PLGA nanoparticles toward lung alveolar epithelial cells. Grabowski N, Hillaireau H, Vergnaud J, et al. Int. J. Pharm. 454(2), 686-94, (2013)

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A novel reusable PAni-PVA-Amylase film: activity and analysis. Singh S, Saikia JP, and Buragohain AK Colloids Surf. B Biointerfaces 106, 46-50, (2013)

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Fabrication of porous polyvinyl alcohol scaffold for bone tissue engineering via selective laser sintering. Shuai C, Mao Z, Lu H, et al. Biofabrication 5(1), 015014, (2013)

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Chlamydia trachomatis polymorphic membrane protein D is a virulence factor involved in early host-cell interactions. Kari L, Southern TR, Downey CJ, et al. Infect. Immun. 82(7), 2756-62, (2014)

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Induction of angiogenesis via topical delivery of basic-fibroblast growth factor from polyvinyl alcohol-dextran blend hydrogel in an ovine model of acute myocardial infarction. Fathi E, Nassiri SM, Atyabi N, et al. J. Tissue Eng. Regen. Med. 7(9), 697-707, (2013)

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Investigation on pretreatment of centrifugal mother liquid produced in the production of polyvinyl chloride by air-Fenton technique. Sun Y, Hua X, Ge R, et al. Environ. Sci. Pollut. Res. Int. 20(8), 5797-805, (2013)

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Interactions of binuclear ruthenium(II) complexes with oligonucleotides in hydrogel matrix: enantioselective threading intercalation into GC context. Hanczyc P, Lincoln P, and Norden B J. Phys. Chem. B 117(10), 2947-54, (2013)

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Characterization of electrospun nanofiber matrices made of collagen blends as potential skin substitutes. Lin HY, Kuo YJ, Chang SH, et al. Biomed. Mater. 8(2), 025009, (2013)

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Preparation and characterization of a photocrosslinkable bioadhesive inspired by marine mussel. Xue J, Wang T, Nie J, et al. J. Photochem. Photobiol. B, Biol. 119, 31-6, (2013)

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Biomimetic composite scaffolds based mineralization of hydroxyapatite on electrospun calcium-containing poly(vinyl alcohol) nanofibers. Chang W, Mu X, Zhu X, et al. Mater. Sci. Eng. C. Mater. Biol. Appl. 33(7), 4369-76, (2013)

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Electrospun chitosan/PEDOT nanofibers. Kiristi M, Oksuz AU, Oksuz L, et al. Mater. Sci. Eng. C. Mater. Biol. Appl. 33(7), 3845-50, (2013)

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Development of a new tissue-equivalent material applied to optimizing surgical accuracy. Jiang S, Su Z, Wang X, et al. Mater. Sci. Eng. C. Mater. Biol. Appl. 33(7), 3768-74, (2013)

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Solution growth of spherulitic rod and platelet calcium phosphate assemblies through polymer-assisted mesoscopic transformations. Kosma VA and Beltsios KG Mater. Sci. Eng. C. Mater. Biol. Appl. 33(4), 2175-91, (2013)

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Chitosan/poly(vinyl alcohol) hydrogel combined with Ad-hTGF-β1 transfected mesenchymal stem cells to repair rabbit articular cartilage defects. Qi BW, Yu AX, Zhu SB, et al. Exp. Biol. Med. (Maywood.) 238(1), 23-30, (2013)

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Preoperative angiography and external carotid artery embolization of juvenile nasopharyngeal angiofibromas in a tertiary referral paediatric centre. Ballah D, Rabinowitz D, Vossough A, et al. Clin. Radiol. 68(11), 1097-106, (2013)

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Optical properties of CdSe nanoparticles embedded in polyvinyl alcohol matrix. Bera S, Mondal SP, and Ray SK J. Nanosci. Nanotechnol. 13(1), 300-5, (2013)

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Novel nanoporous bioceramic spheres for drug delivery application: a preliminary in vitro investigation. Simon D, Manuel S, and Varma H Oral Surg. Oral Med. Oral Pathol. Oral Radiol. 115(3), e7-14, (2013)

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Interventional embolization of giant thoracic tumors before surgical resection. Liu FY, Wang MQ, Fan QS, et al. Acta radiol. 54(1), 61-6, (2013)

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Biodegradation of PVA by the new mixed strains isolated from a de-sizing process. Guo Y, Zhou M, Cui SK, et al. J. Environ. Sci. Health. A. Tox. Hazard. Subst. Environ. Eng. 48(5), 518-25, (2013)

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Polyvinyl alcohol and polyethylene glycol form polymer bodies in the periplasm of Sphingomonads that are able to assimilate them. Kawai F, Kitajima S, Oda K, et al. Arch. Microbiol. 195(2), 131-40, (2013)

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Fabrication and properties of capsicum extract-loaded PVA and CA nanofiber patches. Opanasopit P, Sila-On W, Rojanarata T, et al. Pharm. Dev. Technol. 18(5), 1140-7, (2013)

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β-methasone-containing biodegradable poly(lactide-co-glycolide) acid microspheres for intraarticular injection: effect of formulation parameters on characteristics and in vitro release. Song X, Song SK, Zhao P, et al. Pharm. Dev. Technol. 18(5), 1220-9, (2013)

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Rhizobia survival in seeds coated with polyvinyl alcohol (PVA) electrospun nanofibres. Damasceno R, Roggia I, Pereira C, et al. Can. J. Microbiol. 59(11), 716-9, (2013)

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Uterine fibroid embolisation: initial experience in our local population. Jawad RA, Imaad-ur-Rehman, Rana AI, et al. J. Pak. Med. Assoc. 63(12), 1482-5, (2013)

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Preparation and transdermal diffusion evaluation of the prazosin hydrochloride-loaded electrospun poly(vinyl alcohol) fiber mats. Shen X, Xu Q, Xu S, et al. J. Nanosci. Nanotechnol. 14(7), 5258-65, (2014)

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Protein-polymer functionalized aqueous ferrofluids showing high T2 relaxivity. Bhattacharya S, Sheikh L, Tiwari V, et al. J. Biomed. Nanotechnol. 10(5), 811-9, (2014)

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Thalassospira povalilytica sp. nov., a polyvinyl-alcohol-degrading marine bacterium. Nogi Y, Yoshizumi M, and Miyazaki M Int. J. Syst. Evol. Microbiol. 64(Pt 4), 1149-53, (2014)

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Preparation and properties of a pH sensitive carrier based on three kinds of polymer blend to control the release of 5-amino salicylic acid. Dong Y, Zhou Z, Ding H, et al. Pharm. Dev. Technol. 19(8), 960-7, (2014)

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Role of nasal packing in surgical outcome for chronic rhinosinusitis with polyposis. Verim A, Seneldir L, Naiboğlu B, et al. Laryngoscope 124(7), 1529-35, (2014)

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Merck 14,7585

FT-IR 1 (2), 1174:D / FT-IR 1 (2), 1174:C / FT-IR 2 (3), 4687:D / FT-IR 2 (3), 4688:B / FT-IR 1 (2), 1176:A / FT-IR 1 (2), 1174:B / FT-IR 1 (2), 1175:D / FT-IR 1 (2), 1175:A / FT-IR 1 (2), 1176:D / FT-IR 1 (2), 1175:C / FT-IR 1 (2), 1176:B / IR-Spectra (3), 1577:G / RegBook 1 (2), 3159:D / RegBook 1 (2), 3159:I / RegBook 1 (2), 3159:E / RegBook 1 (2), 3159:F / RegBook 1 (2), 3159:G / Sax 6, 2265 / Structure Index 1, 500:C:2

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