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83885 Aldrich

Rink amide (aminomethyl)polystyrene

extent of labeling: ~1.1 mmol/g loading

Synonym: 4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetomido methyl resin, Fmoc Rink amide, Knorr Linker amide resin

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Properties

Related Categories Chemical Biology, Chemical Synthesis, Peptide Chemistry, Polymer Supports for SPPS, Resins for Fmoc-/tBu-SPPS,
extent of labeling   ~1.1 mmol/g loading
matrix   crosslinked with 1% DVB
particle size   100-200 mesh

Description

Other Notes

Review

Packaging

1, 5 g in glass bottle

Application

• Solid support for Fmoc-based solid phase peptide synthesis (SPPS) of peptide amides.
• This solid support contains a Rink amide linker attached to aminomethylpolystyrene resin.
• Cleavage of peptides is achieved by adding 95% TFA.

Price and Availability


Cross-Coupling Guide
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Rink Amide (RAM) Resins

A broad variety of 4-((2,4-dimethoxyphenyl)(Fmoc-amino)methyl)phenoxyalkyl functionalized supports have been developed for the synthesis of peptide carboxamides.(1, 2) Detachment of peptide amides fr...
ChemFiles Volume 3 Article 4
Keywords: Peptide synthesis, Solid phase peptide synthesis

Peer-Reviewed Papers
15

References

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