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852678 Aldrich

6-Mercaptopurine monohydrate

98%

Synonym: 6-Purinethiol, 6-Thiohypoxanthine

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Properties

Related Categories Antitumor Agents, Building Blocks, Cancer Research, Cell Biology, Chemical Synthesis,
InChI Key   WFFQYWAAEWLHJC-UHFFFAOYSA-N
assay   98%
mp   >300 °C(lit.)

Description

Application

6-Mercaptopurine is a widely used antileukemic agent that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.

Packaging

1, 5 g in glass bottle

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
UP0400000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Nucleotide Synthesis in Cancer Cells

Neoplastic cells are highly dependent on the de novo synthesis of nucleotides to maintain sufficient pools to support DNA replication and the production of RNA. The metabolic pathways supporting nucl...
Keywords: Biofiles, Cancer, Catalysis, Citric Acid Cycle, DNA replication, Gene expression, Glycolysis, Metabolic Pathways, Metabolism, Metabolites, Nucleotide Synthesis, PAGE, Pentose phosphate pathway, Pyrimidine synthesis, Support

Peer-Reviewed Papers
15

References

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