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855057 Aldrich

Betulinic acid

technical grade, 90%

Synonym: 3β-Hydroxy-20(29)-lupaene-28-oic acid

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Properties

Related Categories Anti-proliferative Agents, Asymmetric Synthesis, Cancer Research, Cell Biology, Chemical Synthesis,
grade   technical grade
InChI Key   QGJZLNKBHJESQX-FZFNOLFKSA-N
assay   90%
optical activity   [α]20/D +7.8°, c = 0.9 in pyridine
mp   295-298 °C (dec.)(lit.)
storage temp.   2-8°C

Description

Biochem/physiol Actions

Betulinic acid, a pentacyclic triterpene, selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism.

Packaging

100, 500 mg in glass bottle

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

NF-κB and Inflammation

Chronic inflammation is an underlying factor in the development and progression of many of the chronic diseases of aging, such as arthritis, atherosclerosis, diabetes, and cancer. Oxidative cellular ...
BioFiles 2007, 2.4, 14.
Keywords: Acetylations, Adhesion, Angiogenesis, Apoptosis, Cancer, Carcinogens, Catalysis, Cell culture, Cell proliferation, Cell signaling, Cellular processes, Degradations, Diabetes, Diseases, Environmental, Gene expression, Glycosylations, High performance liquid chromatography, Inflammation, PAGE, Phosphorylations, Thin layer chromatography, Transcription, transformation

Peer-Reviewed Papers
15

References

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