|Related Categories||Chemical Biology, Chemical Synthesis, Coupling, Others, Peptide Chemistry,|
|mp||220 °C (dec.)(lit.)|
1 g in glass bottle
Woodward's reagent K reacts with histidine and cysteine residues in Escherichia coli and Saccharomyces cerevisiae phosphoenolpyruvate carboxykinases. Bustos P, Gajardo MI, Gómez C, et al. J. Protein Chem. 15(5), 467-72, (1996)
A novel method for chemical modification of functional groups other than a carboxyl group in proteins by N-ethyl-5-phenylisooxazolium-3'-sulfonate (Woodward's reagent-K): inhibition of ADP-induced platelet responses involves covalent modification of aggregin, an ADP receptor. Puri RN and Colman RW Anal. Biochem. 240(2), 251-61, (1996)
Woodward's reagent K inactivation of Escherichia coli L-threonine dehydrogenase: increased absorbance at 340-350 nm is due to modification of cysteine and histidine residues, not aspartate or glutamate carboxyl groups. Johnson AR and Dekker EE Protein Sci. 5(2), 382-90, (1996)
Mouse Ae1 E699Q mediates SO42-i/anion-o exchange with [SO42-]i-dependent reversal of wild-type pHo sensitivity. Chernova MN, Stewart AK, Barry PN, et al. Am. J. Physiol. Cell Physiol. 295(2), C302-12, (2008)
Possible involvement of glutamic and/or aspartic acid residue(s) and requirement of mitochondrial integrity for the protective effect of creatine against inhibition of cardiac mitochondrial respiration by methylglyoxal. S. SinhaRoy, et al., Mol. Cell Biochem. 271, 167-176, (2005)
Spectrophotometric tool for the determination of the total carboxylate content in proteins; molar extinction coefficient of the enol ester from Woodward's reagent K reacted with protein carboxylates. Kosters HA and de Jongh HH Anal. Chem. 75(10), 2512-6, (2003)
Evidence for essential histidine and dicarboxylic amino-acid residues in the active site of UDP-glucose : solasodine glucosyltransferase from eggplant leaves. Nawłoka P, Kalinowska M, Paczkowski C, et al. Acta Biochim. Pol. 50(2), 567-72, (2003)
The carboxyl side chain of glutamate 681 interacts with a chloride binding modifier site that allosterically modulates the dimeric conformational state of band 3 (AE1). Implications for the mechanism of anion/proton cotransport. Salhany JM, Sloan RL, and Cordes KS Biochemistry 42(6), 1589-602, (2003)
Inhibitory effects of Woodward's reagent K on carrier-mediated anion transport in rabbit intestinal brush border membrane vesicles. Tam TN and Schron CM Zhonghua Yi Xue Za Zhi (Taipei.) 62(2), 98-106, (1999)
Fieser 1,384 / Fieser 2,197 / Fieser 5,306 / Fieser 8,226
FT-IR 1 (2), 637:B / FT-IR 2 (3), 3542:C / FT-NMR 1 (3), 100:C / IR-Spectra (3), 1229:F / IR-Spectra (2), 1070:A / NMR-Reference 2 (2), 505:D / RegBook 1 (2), 2379:D / Sigma FT-IR 1 (2), 557:B / Structure Index 1, 377:C:5
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