A77903 Aldrich



Synonym: 1-Pyrenamine, 3-Aminopyrene

  • CAS Number 1606-67-3

  • Empirical Formula (Hill Notation) C16H11N

  • Molecular Weight 217.27

  •  Beilstein Registry Number 1875737

  •  EC Number 216-521-3

  •  MDL number MFCD00004140

  •  PubChem Substance ID 24891279

  • Popular Documents:  FTIR (PDF)  



Related Categories Amines, Building Blocks, C15 to C19, Chemical Synthesis, Nitrogen Compounds,
assay   97%
mp   115-117 °C(lit.)



1 g in glass bottle

Price and Availability

Suggested Laboratory Gloves

Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.

Search for Answers, Not Just Materials

Customers Also Viewed

Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
WGK Germany 

Protocols & Articles

Peer-Reviewed Papers


Set your institution to view full text papers.

Determination of 1-hydroxypyrene in human urine by HPLC with electrochemical detection at a boron-doped diamond film electrode. Yosypchuk O, Barek J, and Vyskočil V Anal. Bioanal. Chem 404(3), 693-9, (2012)


Experimental and theoretical studies on pyrene-grafted polyoxometalate hybrid. Gao J, Liu X, Liu Y, et al. Dalton Trans. 41(39), 12185-91, (2012)


Association interaction and voltammetric determination of 1-aminopyrene and 1-hydroxypyrene at cyclodextrin and DNA based electrochemical sensors. Ferancová A, Bucková M, Korgová E, et al. Bioelectrochemistry 67(2), 191-7, (2005)


Ultraviolet radiation increases the toxicity of pyrene, 1-aminopyrene and 1-hydroxypyrene to human keratinocytes. Ekunwe SI, Hunter RD, and Hwang HM Int. J. Environ. Res. Public Health 2(1), 58-62, (2005)


Excess electron transfer dynamics in DNA hairpins conjugated with N,N-dimethylaminopyrene as a photosensitizing electron donor. Park MJ, Fujitsuka M, Nishitera H, et al. Chem. Commun. (Camb.) 48(89), 11008-10, (2012)


Antimutagenicity of some flowers grown in Thailand. Wongwattanasathien O, Kangsadalampai K, and Tongyonk L Food Chem. Toxicol. 48(4), 1045-51, (2010)


Effect of ring size on conformations of aromatic amine-DNA adducts: the aniline-C8 guanine adduct resides in the B-DNA major groove. Shapiro R, Ellis S, Hingerty BE, et al. Chem. Res. Toxicol. 11(4), 335-41, (1998)


Plasmid-mediated expression of the UmuDC mutagenesis proteins in an Escherichia coli strain engineered for human cytochrome P450 1A2-catalyzed activation of aromatic amines. Josephy PD, Evans DH, Williamson V, et al. Mutat. Res. 429(2), 199-208, (1999)


Mechanisms of chemokine responses by polycyclic aromatic hydrocarbons in bronchial epithelial cells: sensitization through toll-like receptor-3 priming. Øvrevik J, Refsnes M, Holme JA, et al. Toxicol. Lett. 219(2), 125-32, (2013)


Surface immobilized optical probes: pyrene molecules covalently attached to silica and indium-doped tin oxide. Mazur M and Blanchard GJ Bioelectrochemistry 66(1-2), 89-94, (2005)


Determining times to maximum urine excretion of 1-aminopyrene after diesel exhaust exposure. Huyck S, Ohman-Strickland P, Zhang L, et al. J. Expo. Sci. Environ. Epidemiol. 20(7), 650-5, (2010)


Using organic nanoparticle fluorescence to determine nitrite in water. Wang L, Dong L, Bian GR, et al. Anal. Bioanal. Chem 382(5), 1300-3, (2005)


Quantitative analysis of the mutagenic potential of 1-aminopyrene-DNA adduct bypass catalyzed by Y-family DNA polymerases. Sherrer SM, Taggart DJ, Pack LR, et al. Mutat. Res. 737(1-2), 25-33, (2012)


Solution conformation of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dC in a DNA duplex. Mao B, Vyas RR, Hingerty BE, et al. Biochemistry 35(39), 12659-70, (1996)


Erythrocyte enzymes catalyze 1-nitropyrene and 3-nitrofluoranthene nitroreduction. Belisario MA, Pecce R, Garofalo A, et al. Toxicology 108(1-2), 101-8, (1996)


Triple recognition of B-DNA. Bert Willis et al Bioorg. Med. Chem. Lett. 19, 4974-9, (2009)


Quantification of 1-aminopyrene in human urine after a controlled exposure to diesel exhaust. Laumbach R, Tong J, Zhang L, et al. J. Environ. Monit. 11(1), 153-9, (2009)


Differential chemokine induction by 1-nitropyrene and 1-aminopyrene in bronchial epithelial cells: importance of the TACE/TGF-α/EGFR-pathway. Øvrevik J, Holme JA, Låg M, et al. Environ. Toxicol. Pharmacol. 35(2), 235-9, (2013)


Metabolic activation of carcinogenic 1-nitropyrene by human cytochrome P450 1B1 in Salmonella typhimurium strain expressing an O-acetyltransferase in SOS/umu assay. Hatanaka N, Yamazaki H, Oda Y, et al. Mutat. Res. 497(1-2), 223-33, (2001)


Solution structure of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dA in a DNA duplex. Gu Z, Gorin A, Krishnasamy R, et al. Biochemistry 38(33), 10843-54, (1999)


Composite poly(methyl methacrylate-methacrylic acid-2-hydroxyethyl methacrylate) latex for immunoassay. The case of plasminogen. Miksa B, Wilczynska M, Cierniewski C, et al. J. Biomater. Sci. Polym. Ed. 7(6), 503-13, (1995)


Chromatographic methods for carcinogenic/mutagenic nitropolycyclic aromatic hydrocarbons. Hayakawa K Biomed. Chromatogr. 14(6), 397-405, (2000)


Biopartitioning micellar chromatography to predict mutagenicity of aromatic amines. S Torres-Cartas et al Eur. J. Med. Chem. 42, 1396-402, (2007)


Photochemical transformation and phototoxicity of 1-aminopyrene. Zeng K, Hwang HM, Dong S, et al. Environ. Toxicol. Chem. 23(6), 1400-7, (2004)


1-Nitropyrene-metabolizing activities of fish liver preparations. Kitamura S and Tatsumi K Bull. Environ. Contam. Toxicol. 58(3), 448-55, (1997)


Effect of river humic acid on 1-aminopyrene ecotoxicity in a dynamic solar photolysis process. Hwang HM, Balarezo AL, Jones VN, et al. Bull. Environ. Contam. Toxicol. 72(5), 1059-66, (2004)


Organic pollution and genotoxicity of sediments of the Palun marshes (Berre lagoon, France). Di Giorgio C, Liu W, Sarrazin L, et al. J. Environ. Qual. 39(2), 558-67, (2010)


Adsorption and covalent immobilization of human serum albumin (HSA) and gamma globulins (gamma G) onto poly(styrene/acrolein) latexes with pyrene, dansyl, and 2,4-dinitrophenyl labels. Miksa B and Slomkowski S J. Biomater. Sci. Polym. Ed. 7(1), 77-96, (1995)


Beil. 12,IV,3460

Corp MSDS 1, 221:C / FT-IR 1 (1), 1256:B / FT-IR 2 (2), 2130:A / IR-Spectra (2), 661:D / IR-Spectra (3), 752:F / NMR-Reference 2 (1), 1066:B / RegBook 1 (1), 1451:E / Sax 6, 2323 / Sigma FT-IR 1 (2), 280:B / Structure Index 1, 226:D:7 / Vapor Phase 3, 1161:D

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?