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A77903 Aldrich

1-Aminopyrene

97%

Synonym: 1-Pyrenamine, 3-Aminopyrene

  • CAS Number 1606-67-3

  • Empirical Formula (Hill Notation) C16H11N

  • Molecular Weight 217.27

  •  Beilstein Registry Number 1875737

  •  EC Number 216-521-3

  •  MDL number MFCD00004140

  •  PubChem Substance ID 24891279

  • Popular Documents:  FTIR (PDF)  

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Properties

Related Categories Amines, Building Blocks, C15 to C19, Chemical Synthesis, Nitrogen Compounds,
assay   97%
mp   115-117 °C(lit.)

Description

Packaging

1 g in glass bottle

Price and Availability

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Safety & Documentation

Safety Information

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GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
WGK Germany 
3
RTECS 
UR2275000

Protocols & Articles

Peer-Reviewed Papers

References

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Determination of 1-hydroxypyrene in human urine by HPLC with electrochemical detection at a boron-doped diamond film electrode. Yosypchuk O, Barek J, and Vyskočil V Anal. Bioanal. Chem 404(3), 693-9, (2012)

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Experimental and theoretical studies on pyrene-grafted polyoxometalate hybrid. Gao J, Liu X, Liu Y, et al. Dalton Trans. 41(39), 12185-91, (2012)

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Association interaction and voltammetric determination of 1-aminopyrene and 1-hydroxypyrene at cyclodextrin and DNA based electrochemical sensors. Ferancová A, Bucková M, Korgová E, et al. Bioelectrochemistry 67(2), 191-7, (2005)

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Ultraviolet radiation increases the toxicity of pyrene, 1-aminopyrene and 1-hydroxypyrene to human keratinocytes. Ekunwe SI, Hunter RD, and Hwang HM Int. J. Environ. Res. Public Health 2(1), 58-62, (2005)

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Excess electron transfer dynamics in DNA hairpins conjugated with N,N-dimethylaminopyrene as a photosensitizing electron donor. Park MJ, Fujitsuka M, Nishitera H, et al. Chem. Commun. (Camb.) 48(89), 11008-10, (2012)

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Antimutagenicity of some flowers grown in Thailand. Wongwattanasathien O, Kangsadalampai K, and Tongyonk L Food Chem. Toxicol. 48(4), 1045-51, (2010)

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Effect of ring size on conformations of aromatic amine-DNA adducts: the aniline-C8 guanine adduct resides in the B-DNA major groove. Shapiro R, Ellis S, Hingerty BE, et al. Chem. Res. Toxicol. 11(4), 335-41, (1998)

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Plasmid-mediated expression of the UmuDC mutagenesis proteins in an Escherichia coli strain engineered for human cytochrome P450 1A2-catalyzed activation of aromatic amines. Josephy PD, Evans DH, Williamson V, et al. Mutat. Res. 429(2), 199-208, (1999)

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Mechanisms of chemokine responses by polycyclic aromatic hydrocarbons in bronchial epithelial cells: sensitization through toll-like receptor-3 priming. Øvrevik J, Refsnes M, Holme JA, et al. Toxicol. Lett. 219(2), 125-32, (2013)

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Surface immobilized optical probes: pyrene molecules covalently attached to silica and indium-doped tin oxide. Mazur M and Blanchard GJ Bioelectrochemistry 66(1-2), 89-94, (2005)

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Determining times to maximum urine excretion of 1-aminopyrene after diesel exhaust exposure. Huyck S, Ohman-Strickland P, Zhang L, et al. J. Expo. Sci. Environ. Epidemiol. 20(7), 650-5, (2010)

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Using organic nanoparticle fluorescence to determine nitrite in water. Wang L, Dong L, Bian GR, et al. Anal. Bioanal. Chem 382(5), 1300-3, (2005)

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Quantitative analysis of the mutagenic potential of 1-aminopyrene-DNA adduct bypass catalyzed by Y-family DNA polymerases. Sherrer SM, Taggart DJ, Pack LR, et al. Mutat. Res. 737(1-2), 25-33, (2012)

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Solution conformation of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dC in a DNA duplex. Mao B, Vyas RR, Hingerty BE, et al. Biochemistry 35(39), 12659-70, (1996)

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Erythrocyte enzymes catalyze 1-nitropyrene and 3-nitrofluoranthene nitroreduction. Belisario MA, Pecce R, Garofalo A, et al. Toxicology 108(1-2), 101-8, (1996)

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Triple recognition of B-DNA. Bert Willis et al Bioorg. Med. Chem. Lett. 19, 4974-9, (2009)

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Quantification of 1-aminopyrene in human urine after a controlled exposure to diesel exhaust. Laumbach R, Tong J, Zhang L, et al. J. Environ. Monit. 11(1), 153-9, (2009)

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Differential chemokine induction by 1-nitropyrene and 1-aminopyrene in bronchial epithelial cells: importance of the TACE/TGF-α/EGFR-pathway. Øvrevik J, Holme JA, Låg M, et al. Environ. Toxicol. Pharmacol. 35(2), 235-9, (2013)

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Metabolic activation of carcinogenic 1-nitropyrene by human cytochrome P450 1B1 in Salmonella typhimurium strain expressing an O-acetyltransferase in SOS/umu assay. Hatanaka N, Yamazaki H, Oda Y, et al. Mutat. Res. 497(1-2), 223-33, (2001)

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Solution structure of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dA in a DNA duplex. Gu Z, Gorin A, Krishnasamy R, et al. Biochemistry 38(33), 10843-54, (1999)

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Composite poly(methyl methacrylate-methacrylic acid-2-hydroxyethyl methacrylate) latex for immunoassay. The case of plasminogen. Miksa B, Wilczynska M, Cierniewski C, et al. J. Biomater. Sci. Polym. Ed. 7(6), 503-13, (1995)

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Chromatographic methods for carcinogenic/mutagenic nitropolycyclic aromatic hydrocarbons. Hayakawa K Biomed. Chromatogr. 14(6), 397-405, (2000)

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Biopartitioning micellar chromatography to predict mutagenicity of aromatic amines. S Torres-Cartas et al Eur. J. Med. Chem. 42, 1396-402, (2007)

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Photochemical transformation and phototoxicity of 1-aminopyrene. Zeng K, Hwang HM, Dong S, et al. Environ. Toxicol. Chem. 23(6), 1400-7, (2004)

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1-Nitropyrene-metabolizing activities of fish liver preparations. Kitamura S and Tatsumi K Bull. Environ. Contam. Toxicol. 58(3), 448-55, (1997)

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Effect of river humic acid on 1-aminopyrene ecotoxicity in a dynamic solar photolysis process. Hwang HM, Balarezo AL, Jones VN, et al. Bull. Environ. Contam. Toxicol. 72(5), 1059-66, (2004)

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Organic pollution and genotoxicity of sediments of the Palun marshes (Berre lagoon, France). Di Giorgio C, Liu W, Sarrazin L, et al. J. Environ. Qual. 39(2), 558-67, (2010)

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Adsorption and covalent immobilization of human serum albumin (HSA) and gamma globulins (gamma G) onto poly(styrene/acrolein) latexes with pyrene, dansyl, and 2,4-dinitrophenyl labels. Miksa B and Slomkowski S J. Biomater. Sci. Polym. Ed. 7(1), 77-96, (1995)

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Beil. 12,IV,3460

Corp MSDS 1, 221:C / FT-IR 1 (1), 1256:B / FT-IR 2 (2), 2130:A / IR-Spectra (2), 661:D / IR-Spectra (3), 752:F / NMR-Reference 2 (1), 1066:B / RegBook 1 (1), 1451:E / Sax 6, 2323 / Sigma FT-IR 1 (2), 280:B / Structure Index 1, 226:D:7 / Vapor Phase 3, 1161:D

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