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B56501 Aldrich

4-Bromoanisole

≥99.0%

Synonym: 1-Bromo-4-methoxybenzene

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Properties

Related Categories Building Blocks, C2 to C7, Chemical Synthesis, Ethers, Organic Building Blocks,
InChI Key   QJPJQTDYNZXKQF-UHFFFAOYSA-N
assay   ≥99.0%
refractive index   n20/D 1.564(lit.)
bp   223 °C(lit.)
mp   9-10 °C(lit.)
density   1.494 g/mL at 25 °C(lit.)

Description

Packaging

50, 100, 500 g in glass bottle

Application

4-Bromoanisole was used in the synthesis of aryl 1,3-diketones.

General description

4-Bromoanisole is a useful brominating reagent. It is formed as reaction product in the reaction between HOBr and anisole. Suzuki coupling of 4-bromoanisole with phenylboronic acid catalyzed by palladium pincer complexes has been studied. Heck Reaction of 4-bromoanisole with ethyl acrylates in room-temperature ionic liquids is reported to afford ethyl 4-methoxycinnamate.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
BZ8501000
Flash Point(F) 
208.4 °F
Flash Point(C) 
98 °C
Protocols & Articles

Articles

Heck Reaction

The Heck reaction is the palladium catalyzed cross-coupling reaction between alkenes, and aryl or vinyl halides (or triflates) to afford substituted alkenes.1,2 It is a useful carbon–carbon bond form...
Keywords: Asymmetric synthesis, Cancer, Catalysis, Coupling reactions, Cross couplings, Heck Reaction, Herbicides, Ligands, Organic synthesis, Solvents

Pd(PhCN)2Cl2/P(t-Bu)3: A Versatile Catalyst for Sonogashira Reactions of Aryl Bromides at Room Temperature

The Suzuki-Miyaura cross-coupling of unprotected, nitrogen-rich heterocycles using precatalysts P1 or P2 is reported. The procedure allows for the reaction of variously substituted indazole, benzimid...
Keywords: Catalysis, Chromatography, Column chromatography, Coupling reactions, Cross couplings

Peer-Reviewed Papers
15

References

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