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C11006 Aldrich

Carbohydrazide

98%

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Properties

Related Categories Building Blocks, Carbonyl Compounds, Chemical Synthesis, Hydrazides, Organic Building Blocks More...
assay   98%
mp   150-153 °C(lit.)

Description

Packaging

25, 100 g in glass bottle

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Semicarbazide

6 wt. % (on silica gel)

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
Supplemental Hazard Statements 
Risk of explosion if heated under confinement.
Personal Protective Equipment 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
2
RTECS 
FF2625000

Protocols & Articles

Peer-Reviewed Papers

References

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Critical assessment of rhBMP-2 mediated bone induction: an in vitro and in vivo evaluation. Kisiel M, Ventura M, Oommen OP, et al. J. Control. Release 162(3), 646-53, (2012)

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A hydrazine- and phosgene-free synthesis of tetrazinanones, precursors to 1,5-dialkyl-6-oxoverdazyl radicals. Bancerz M, Youn B, DaCosta MV, et al. J. Org. Chem. 77(5), 2415-21, (2012)

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Identification of 1,3-diiminoisoindoline carbohydrazides as potential antimalarial candidates. Mombelli P, Witschel MC, van Zijl AW, et al. ChemMedChem 7(1), 151-8, (2012)

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Design, synthesis and docking studies of new 4-hydroxyquinoline-3-carbohydrazide derivatives as anti-HIV-1 agents. Hajimahdi Z, Zabihollahi R, Aghasadeghi MR, et al. Drug Res. (Stuttg.) 63(4), 192-7, (2013)

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[Study on inhibition of NO(x) and dioxin emissions by carbohydrazide under moderate to high temperatures]. Guan ZZ, Chen DZ, Hong X, et al. Huan Jing Ke Xue 32(9), 2810-6, (2011)

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Design and synthesis of novel thiophenecarbohydrazide, thienopyrazole and thienopyrimidine derivatives as antioxidant and antitumor agents. Abu-Hashem AA, El-Shehry MF, and Badria FA Acta. Pharm. 60(3), 311-23, (2010)

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A screened hybrid density functional study on energetic complexes: cobalt, nickel and copper carbohydrazide perchlorates. Huang H, Zhang T, Zhang J, et al. J. Hazard. Mater. 179(1-3), 21-7, (2010)

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Synthesis, biological assessment and molecular modeling of new dihydroquinoline-3-carboxamides and dihydroquinoline-3-carbohydrazide derivatives as cholinesterase inhibitors, and Ca channel antagonists. Tomassoli I, Ismaili L, Pudlo M, et al. Eur. J. Med. Chem. 46(1), 1-10, (2011)

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Synthesis and biological evaluation of benzimidazole-5-carbohydrazide derivatives as antimalarial, cytotoxic and antitubercular agents. José Camacho et al Bioorg. Med. Chem. 19, 2023-9, (2011)

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Schiff bases of indoline-2,3-dione (isatin) derivatives and nalidixic acid carbohydrazide, synthesis, antitubercular activity and pharmacophoric model building. Tarek Aboul-Fadl et al Eur. J. Med. Chem. 45, 4578-86, (2010)

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Design, synthesis and docking studies of new quinoline-3-carbohydrazide derivatives as antitubercular agents. K D Thomas et al Eur. J. Med. Chem. 46, 5283-92, (2011)

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Synthesis, antitubercular activity, and SAR study of N-substituted-phenylamino-5-methyl-1H-1,2,3-triazole-4-carbohydrazides. Jordão AK, Sathler PC, Ferreira VF, et al. Bioorg. Med. Chem. 19(18), 5605-11, (2011)

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Probing the dynamic reversibility and generation of dynamic combinatorial libraries in the presence of bacterial model oligopeptides as templating guests of tetra-carbohydrazide macrocycles using electrospray mass spectrometry. Nour HF, Islam T, Fernández-Lahore M, et al. Rapid Commun. Mass Spectrom. 26(24), 2865-76, (2012)

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Synthesis and cytotoxic activity of novel 3-(1H-indol-3-yl)-1H-pyrazole-5-carbohydrazide derivatives. Datong Zhang et al Eur. J. Med. Chem. 46, 5868-77, (2011)

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Synthesis, crystal structures, insecticidal activities, and structure--activity relationships of novel N'-tert-Butyl-N'-substituted-benzoyl-N-[di(octa)hydro]benzofuran{(2,3-dihydro)benzo[1,3]([1,4])dioxine}carbohydrazide derivatives. Huang Z, Liu Y, Li Y, et al. J. Agric. Food Chem. 59(2), 635-44, (2011)

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Synthesis, spectroscopic characterization and biological evaluation studies of Schiff's base derived from naphthofuran-2-carbohydrazide with 8-formyl-7-hydroxy-4-methyl coumarin and its metal complexes. Halli MB, Sumathi RB, and Kinni M Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 99, 46-56, (2012)

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Rapid synthesis and in vitro and in vivo evaluation of folic acid derivatives labeled with fluorine-18 for PET imaging of folate receptor-positive tumors. Al Jammaz I, Al-Otaibi B, Amer S, et al. Nucl. Med. Biol. 38(7), 1019-28, (2011)

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Azabicyclo[3.1.0]hexane-1-carbohydrazides as potent and selective GHSR1a ligands presenting a specific in vivo behavior. Sabbatini FM, Melotto S, Bernasconi G, et al. ChemMedChem 6(11), 1981-5, (2011)

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Synthesis and evaluation of novel chloropyrrole molecules designed by molecular hybridization of common pharmacophores as potential antimicrobial agents. Rajesh A Rane et al Bioorg. Med. Chem. Lett. 20, 5681-5, (2010)

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Design & synthesis of N'-[substituted] pyridine-4-carbohydrazides as potential anticonvulsant agents. Laxmi Tripathi et al Eur. J. Med. Chem. 46, 509-18, (2011)

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Discovery process and characterization of novel carbohydrazide derivatives as potent and selective GHSR1a antagonists. Sabbatini FM, Di Fabio R, Corsi M, et al. ChemMedChem 5(9), 1450-5, (2010)

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The histopathological and immunological pattern of CBA mice infected with Leishmania amazonensis after treatment with pyrazole carbohydrazide derivatives. Charret KS, Lagrota-Cândido J, Carvalho-Pinto CE, et al. Exp. Parasitol. 133(2), 201-10, (2013)

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Synthesis and antimicrobial activity of N'-heteroarylidene-1-adamantylcarbohydrazides and (±)-2-(1-adamantyl)-4-acetyl-5-[5-(4-substituted phenyl-3-isoxazolyl)]-1,3,4-oxadiazolines. El-Emam AA, Alrashood KA, Al-Omar MA, et al. Molecules 17(3), 3475-83, (2012)

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Synthesis and antimycobacterial evaluation of N'-(E)-heteroaromaticpyrazine-2-carbohydrazide derivatives. Lima CH, Henriques MG, Candéa AL, et al. Med. Chem. 7(3), 245-9, (2011)

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Novel indoline-1- or 3,4-dihydroquinoline-1(2H)-substituted carbothiohydrazides as TPO receptor agonists. Tang PC, Lu HJ, Chen YQ, et al. Bioorg. Med. Chem. Lett. 20(19), 5670-2, (2010)

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Merck 14,1804

Beil. 3,IV,240

FT-IR 2 (1), 1366:D / FT-IR 1 (1), 805:A / IR-Spectra (3), 477:D / IR-Spectra (2), 423:C / NMR-Reference 2 (1), 675:A / RegBook 1 (1), 945:B / Sax 6, 639 / Structure Index 1, 147:B:2

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