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C11006 Aldrich

Carbohydrazide

98%

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Properties

Related Categories Building Blocks, Carbonyl Compounds, Chemical Synthesis, Hydrazides, Organic Building Blocks More...
assay   98%
mp   150-153 °C(lit.)

Description

Packaging

25, 100 g in glass bottle

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Semicarbazide

6 wt. % (on silica gel)

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
Supplemental Hazard Statements 
Risk of explosion if heated under confinement.
Personal Protective Equipment 
Hazard Codes (Europe) 
Risk Statements (Europe) 
Safety Statements (Europe) 
36/37-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
2
RTECS 
FF2625000

Protocols & Articles

Peer-Reviewed Papers

References

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Critical assessment of rhBMP-2 mediated bone induction: an in vitro and in vivo evaluation. Kisiel M, Ventura M, Oommen OP, et al. J. Control. Release 162(3), 646-53, (2012)

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A hydrazine- and phosgene-free synthesis of tetrazinanones, precursors to 1,5-dialkyl-6-oxoverdazyl radicals. Bancerz M, Youn B, DaCosta MV, et al. J. Org. Chem. 77(5), 2415-21, (2012)

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Identification of 1,3-diiminoisoindoline carbohydrazides as potential antimalarial candidates. Mombelli P, Witschel MC, van Zijl AW, et al. ChemMedChem 7(1), 151-8, (2012)

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Design, synthesis and docking studies of new 4-hydroxyquinoline-3-carbohydrazide derivatives as anti-HIV-1 agents. Hajimahdi Z, Zabihollahi R, Aghasadeghi MR, et al. Drug Res. (Stuttg.) 63(4), 192-7, (2013)

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[Study on inhibition of NO(x) and dioxin emissions by carbohydrazide under moderate to high temperatures]. Guan ZZ, Chen DZ, Hong X, et al. Huan Jing Ke Xue 32(9), 2810-6, (2011)

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Design and synthesis of novel thiophenecarbohydrazide, thienopyrazole and thienopyrimidine derivatives as antioxidant and antitumor agents. Abu-Hashem AA, El-Shehry MF, and Badria FA Acta. Pharm. 60(3), 311-23, (2010)

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A screened hybrid density functional study on energetic complexes: cobalt, nickel and copper carbohydrazide perchlorates. Huang H, Zhang T, Zhang J, et al. J. Hazard. Mater. 179(1-3), 21-7, (2010)

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Synthesis, biological assessment and molecular modeling of new dihydroquinoline-3-carboxamides and dihydroquinoline-3-carbohydrazide derivatives as cholinesterase inhibitors, and Ca channel antagonists. Tomassoli I, Ismaili L, Pudlo M, et al. Eur. J. Med. Chem. 46(1), 1-10, (2011)

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Synthesis and biological evaluation of benzimidazole-5-carbohydrazide derivatives as antimalarial, cytotoxic and antitubercular agents. José Camacho et al Bioorg. Med. Chem. 19, 2023-9, (2011)

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Schiff bases of indoline-2,3-dione (isatin) derivatives and nalidixic acid carbohydrazide, synthesis, antitubercular activity and pharmacophoric model building. Tarek Aboul-Fadl et al Eur. J. Med. Chem. 45, 4578-86, (2010)

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Design, synthesis and docking studies of new quinoline-3-carbohydrazide derivatives as antitubercular agents. K D Thomas et al Eur. J. Med. Chem. 46, 5283-92, (2011)

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Synthesis, antitubercular activity, and SAR study of N-substituted-phenylamino-5-methyl-1H-1,2,3-triazole-4-carbohydrazides. Jordão AK, Sathler PC, Ferreira VF, et al. Bioorg. Med. Chem. 19(18), 5605-11, (2011)

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Probing the dynamic reversibility and generation of dynamic combinatorial libraries in the presence of bacterial model oligopeptides as templating guests of tetra-carbohydrazide macrocycles using electrospray mass spectrometry. Nour HF, Islam T, Fernández-Lahore M, et al. Rapid Commun. Mass Spectrom. 26(24), 2865-76, (2012)

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Synthesis and cytotoxic activity of novel 3-(1H-indol-3-yl)-1H-pyrazole-5-carbohydrazide derivatives. Datong Zhang et al Eur. J. Med. Chem. 46, 5868-77, (2011)

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Synthesis, crystal structures, insecticidal activities, and structure--activity relationships of novel N'-tert-Butyl-N'-substituted-benzoyl-N-[di(octa)hydro]benzofuran{(2,3-dihydro)benzo[1,3]([1,4])dioxine}carbohydrazide derivatives. Huang Z, Liu Y, Li Y, et al. J. Agric. Food Chem. 59(2), 635-44, (2011)

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Synthesis, spectroscopic characterization and biological evaluation studies of Schiff's base derived from naphthofuran-2-carbohydrazide with 8-formyl-7-hydroxy-4-methyl coumarin and its metal complexes. Halli MB, Sumathi RB, and Kinni M Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 99, 46-56, (2012)

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Rapid synthesis and in vitro and in vivo evaluation of folic acid derivatives labeled with fluorine-18 for PET imaging of folate receptor-positive tumors. Al Jammaz I, Al-Otaibi B, Amer S, et al. Nucl. Med. Biol. 38(7), 1019-28, (2011)

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Azabicyclo[3.1.0]hexane-1-carbohydrazides as potent and selective GHSR1a ligands presenting a specific in vivo behavior. Sabbatini FM, Melotto S, Bernasconi G, et al. ChemMedChem 6(11), 1981-5, (2011)

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Synthesis and evaluation of novel chloropyrrole molecules designed by molecular hybridization of common pharmacophores as potential antimicrobial agents. Rajesh A Rane et al Bioorg. Med. Chem. Lett. 20, 5681-5, (2010)

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Design & synthesis of N'-[substituted] pyridine-4-carbohydrazides as potential anticonvulsant agents. Laxmi Tripathi et al Eur. J. Med. Chem. 46, 509-18, (2011)

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Discovery process and characterization of novel carbohydrazide derivatives as potent and selective GHSR1a antagonists. Sabbatini FM, Di Fabio R, Corsi M, et al. ChemMedChem 5(9), 1450-5, (2010)

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The histopathological and immunological pattern of CBA mice infected with Leishmania amazonensis after treatment with pyrazole carbohydrazide derivatives. Charret KS, Lagrota-Cândido J, Carvalho-Pinto CE, et al. Exp. Parasitol. 133(2), 201-10, (2013)

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Synthesis and antimicrobial activity of N'-heteroarylidene-1-adamantylcarbohydrazides and (±)-2-(1-adamantyl)-4-acetyl-5-[5-(4-substituted phenyl-3-isoxazolyl)]-1,3,4-oxadiazolines. El-Emam AA, Alrashood KA, Al-Omar MA, et al. Molecules 17(3), 3475-83, (2012)

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Synthesis and antimycobacterial evaluation of N'-(E)-heteroaromaticpyrazine-2-carbohydrazide derivatives. Lima CH, Henriques MG, Candéa AL, et al. Med. Chem. 7(3), 245-9, (2011)

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Novel indoline-1- or 3,4-dihydroquinoline-1(2H)-substituted carbothiohydrazides as TPO receptor agonists. Tang PC, Lu HJ, Chen YQ, et al. Bioorg. Med. Chem. Lett. 20(19), 5670-2, (2010)

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Merck 14,1804

Beil. 3,IV,240

FT-IR 2 (1), 1366:D / FT-IR 1 (1), 805:A / IR-Spectra (3), 477:D / IR-Spectra (2), 423:C / NMR-Reference 2 (1), 675:A / RegBook 1 (1), 945:B / Sax 6, 639 / Structure Index 1, 147:B:2

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