• USA Home
  • C92006 - Indole-5-carbonitrile

EMAIL THIS PAGE TO A FRIEND
C92006 Aldrich

Indole-5-carbonitrile

99%

Synonym: 5-Cyanoindole

Purchase

Properties

Related Categories Building Blocks, C7 to C9, Chemical Synthesis, Heterocyclic Building Blocks, Indoles More...
InChI Key   YHYLDEVWYOFIJK-UHFFFAOYSA-N
assay   99%
mp   106-108 °C(lit.)

Description

Packaging

5, 10 g in glass bottle

Application

• Reactant for parallel synthesis of dihydroisoquinolines via silver and L-proline co-catalyzed three-component coupling reaction
• Reactant for chemoselective and regioselective preparation of benzoyl indoles
• Reactant for preparation of novel PPARα/γ dual agonists for potential treatment of metabolic syndrome and IDDM
• Reactant for preparation of 4,5-dihydrocyclopenta[c]quinolines by palladium-catalyzed ring-expansion reaction alkynes, using O2 as the oxidant
• Reactant for preparation of vinylindoles by hydroarylation of alkynes using indium bromide catalyst
• Reactant for gold catalyzed direct alkynylation using a benziodoxolone based hypervalent iodine reagent

Price and Availability

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
NL5993120
Protocols & Articles

Articles

Indoles

Sigma-Aldrich is proud to offer a new series of ChemFiles—called Privileged Structures, to our Drug Discovery and Organic Synthesis customers. Each piece will highlight a specific motif, selected app...
Chemfiles Volume 4 Article 8
Keywords: Applications, Building blocks, Cardiovascular, Chemfiles, Company, Diabetes, Diseases, Drug discovery, Medicinal chemistry, Organic synthesis, Respiratory

Related Content

Indoles, Purines, and Their Isosteres

Substituted indoles and purines have frequently been referred to as “privileged structures” since they are capable of binding to multiple receptors with high affinity, and thus have applications acro...
Keywords: Building blocks, Medicinal chemistry

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?