N,N′-Dicyclohexylcarbodiimide, 99% | C6H11N=C=NC6H11

Properties

Related Categories	Bioactive Small Molecules, Carbodiimides, Cell Biology, Chemical Synthesis, Coupling, D-DIF, Synthetic Reagents More...
assay	99%
bp	122-124 °C/6 mmHg(lit.)
mp	34-35 °C(lit.)
Gene Information	human ... EPHX2(2053) mouse ... Ephx2(13850)

Description

Application

Carboxy group activating reagent for peptide synthesis.¹

Packaging

1 kg in poly bottle

25, 100, 500 g in poly bottle

5 kg in poly drum

Price and Availability

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Related Papers

Archazolid A Binds To The Equatorial Region Of The C-Ring Of The Vacuolar H+-ATPase. Bockelmann, S., et al. J. Thorac. Cardiovasc. Surg. 285, 38304-14, (2010)

Documents

Certificate of Analysis

Certificate of Origin

ChemFiles Vol 7 No 2 (1.25 MB )

FT-IR Condensed Phase

FT-IR Raman

FT-NMR

Pressure-Temperature Nomograph

Safety Information

Symbol	GHS05, GHS06
Signal word	Danger
Hazard statements	H302-H311-H317-H318
Precautionary statements	P280-P305 + P351 + P338-P312
Personal Protective Equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes (Europe)	T
Risk Statements (Europe)	22-24-41-43
Safety Statements (Europe)	24-26-37/39-45
RIDADR	UN 2811 6.1/PG 2
WGK Germany	1
RTECS	FF2160000
Flash Point(F)	235.4 °F
Flash Point(C)	113 °C

Technical information & documentation associated with this product is available in the Safety & Documentation tab.

Articles

Carbodiimides

Carbodiimide-mediated peptide coupling remains to the most frequently used technique. As a major advantage, carbodiimides do not require prior activation of the carboxylic acid. Dicyclohexylcarbodiim...
Matthias Junkers
Aldrich ChemFiles 2007, 7.2, 5.
Keywords: Cyclizations, Peptide synthesis, Solid phase peptide synthesis

Papers

Set your institution to view full text papers.

1. Jones, J. The Chemical Synthesis of Peptides, International Series of Monographs on Chemistry Oxford , (1994) 23

Archazolid A Binds To The Equatorial Region Of The C-Ring Of The Vacuolar H+-ATPase. Bockelmann, S., et al. J. Thorac. Cardiovasc. Surg. 285, 38304-14, (2010)

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Influence of surface charge on the potential toxicity of PLGA nanoparticles towards Calu-3 cells. Simona Mura et al Int. J. Nanomedicine 6, 2591-605, (2011)

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Pyrrolidine dithiocarbamate and diethyldithiocarbamate are active against growing and nongrowing persister Mycobacterium tuberculosis. Sean T Byrne et al Antimicrob. Agents Chemother. 51, 4495-7, (2007)

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Merck 14,3096

Beil. 12,IV,72

Fieser 1,231 / Fieser 2,126 / Fieser 3,91 / Fieser 4,141 / Fieser 5,206 / Fieser 6,174 / Fieser 7,100 / Fieser 8,162 / Fieser 9,156 / Fieser 10,142 / Fieser 13,107 / Fieser 14,131 / Fieser 15,131 / Fieser 16,128

Aldrich MSDS 1, 648:D / Corp MSDS 1 (1), 1178:B / FT-IR 2 (1), 1485:C / FT-IR 1 (1), 876:C / FT-NMR 1 (1), 1413:B / IR-Spectra (2), 464:H / IR-Spectra (3), 524:C / NMR-Reference 2 (1), 730:A / RegBook 1 (1), 1035:C / Sigma FT-IR 1 (2), 454:C / Structure Index 1, 160:A:8 / Vapor Phase 3, 829:B