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D80800 Aldrich

N,N′-Dicyclohexylurea

98%

Synonym: 1,3-Dicyclohexylurea

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Properties

Related Categories Building Blocks, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks, Ureas More...
assay   98%
mp   232-233 °C(lit.)
Gene Information   human ... EPHX2(2053)
mouse ... Ephx2(13850)

Description

Packaging

25 g in poly bottle

Price and Availability

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
Hazard Codes (Europe) 
Risk Statements (Europe) 
Safety Statements (Europe) 
61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Peer-Reviewed Papers

References

Set your institution to view full text papers.

Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Yu Z, Xu F, Huse LM, et al. Circ. Res. 87(11), 992-8, (2000)

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Orally bioavailable potent soluble epoxide hydrolase inhibitors. Sung Hee Hwang et al J. Med. Chem. 50, 3825-40, (2007)

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Development of Ecom₅₀ and retention index models for nontargeted metabolomics: identification of 1,3-dicyclohexylurea in human serum by HPLC/mass spectrometry. Hall LM, Hall LH, Kertesz TM, et al. J. Chem. Inf. Model. 52(5), 1222-37, (2012)

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Design, synthesis and evaluation of non-urea inhibitors of soluble epoxide hydrolase. Stevan Pecic et al Bioorg. Med. Chem. Lett. 22, 601-5, (2012)

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14,15-Dihydroxyeicosatrienoic acid activates peroxisome proliferator-activated receptor-alpha. Fang X, Hu S, Xu B, et al. Am. J. Physiol. Heart Circ. Physiol. 290(1), H55-63, (2006)

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Rapid determination of soluble epoxide hydrolase inhibitors in rat hepatic microsomes by high-performance liquid chromatography with electrospray tandem mass spectrometry. Watanabe T and Hammock BD Anal. Biochem. 299(2), 227-34, (2001)

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Thermal degradation of amorphous glibenclamide. Rehder S, Sakmann A, Rades T, et al. Eur. J. Pharm. Biopharm. 80(1), 203-8, (2012)

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Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats. Ghosh S, Chiang PC, Wahlstrom JL, et al. Basic Clin Pharmacol Toxicol. 102(5), 453-8, (2008)

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The solid state structure and reactivity of NbCl(5) x (N,N'-dicyclohexylurea) in solution: evidence for co-ordinated urea dehydration to the relevant carbodiimide. Aresta M, Dibenedetto A, Stufano P, et al. Dalton Trans. 39(30), 6985-92, (2010)

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Reinvestigation of the reactions of carbodiimides with alkoxycarbonylamino acid symmetrical anhydrides. Isolation of two N-acylureas. Int. J. Pept. Protein Res. 43, 184, (1994)

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Beil. 12,II,11

FT-IR 2 (1), 1362:A / FT-IR 1 (1), 802:D / FT-NMR 1 (1), 1310:B / IR-Spectra (3), 475:H / IR-Spectra (2), 422:B / NMR-Reference 2 (1), 672:C / RegBook 1 (1), 941:I / Structure Index 1, 146:A:6

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