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D80800 Aldrich

N,N′-Dicyclohexylurea

98%

Synonym: 1,3-Dicyclohexylurea

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Properties

Related Categories Building Blocks, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks, Ureas More...
assay   98%
mp   232-233 °C(lit.)
Gene Information   human ... EPHX2(2053)
mouse ... Ephx2(13850)

Description

Packaging

25 g in poly bottle

Price and Availability


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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Peer-Reviewed Papers

References

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Development of Ecom₅₀ and retention index models for nontargeted metabolomics: identification of 1,3-dicyclohexylurea in human serum by HPLC/mass spectrometry. Hall LM, Hall LH, Kertesz TM, et al. J. Chem. Inf. Model. 52(5), 1222-37, (2012)

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Thermal degradation of amorphous glibenclamide. Rehder S, Sakmann A, Rades T, et al. Eur. J. Pharm. Biopharm. 80(1), 203-8, (2012)

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Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Yu Z, Xu F, Huse LM, et al. Circ. Res. 87(11), 992-8, (2000)

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Orally bioavailable potent soluble epoxide hydrolase inhibitors. Sung Hee Hwang et al J. Med. Chem. 50, 3825-40, (2007)

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14,15-Dihydroxyeicosatrienoic acid activates peroxisome proliferator-activated receptor-alpha. Fang X, Hu S, Xu B, et al. Am. J. Physiol. Heart Circ. Physiol. 290(1), H55-63, (2006)

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Reinvestigation of the reactions of carbodiimides with alkoxycarbonylamino acid symmetrical anhydrides. Isolation of two N-acylureas. Int. J. Pept. Protein Res. 43, 184, (1994)

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Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats. Ghosh S, Chiang PC, Wahlstrom JL, et al. Basic Clin Pharmacol Toxicol. 102(5), 453-8, (2008)

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Design, synthesis and evaluation of non-urea inhibitors of soluble epoxide hydrolase. Stevan Pecic et al Bioorg. Med. Chem. Lett. 22, 601-5, (2012)

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The solid state structure and reactivity of NbCl(5) x (N,N'-dicyclohexylurea) in solution: evidence for co-ordinated urea dehydration to the relevant carbodiimide. Aresta M, Dibenedetto A, Stufano P, et al. Dalton Trans. 39(30), 6985-92, (2010)

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Rapid determination of soluble epoxide hydrolase inhibitors in rat hepatic microsomes by high-performance liquid chromatography with electrospray tandem mass spectrometry. Watanabe T and Hammock BD Anal. Biochem. 299(2), 227-34, (2001)

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Beil. 12,II,11

FT-IR 2 (1), 1362:A / FT-IR 1 (1), 802:D / FT-NMR 1 (1), 1310:B / IR-Spectra (3), 475:H / IR-Spectra (2), 422:B / NMR-Reference 2 (1), 672:C / RegBook 1 (1), 941:I / Structure Index 1, 146:A:6

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