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E33505 Aldrich

Ethyl isonipecotate

98%

Synonym: Ethyl 4-piperidinecarboxylate, Piperidin-4-carboxylic acid ethyl ester

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Properties

Related Categories Building Blocks, C8, Chemical Synthesis, Heterocyclic Building Blocks, Piperidines More...
InChI Key   RUJPPJYDHHAEEK-UHFFFAOYSA-N
assay   98%
refractive index   n20/D 1.459(lit.)
bp   204 °C(lit.)
density   1.02 g/mL at 25 °C(lit.)

Description

Packaging

25, 100 g in glass bottle

Application

Reactant for synthesis of:
• SMN protein modulators
• β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition
• Nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone
• RhoA inhibitors for cardiovascular disease therapy
• Saccharin derived Mannich bases as antimicrobials and antioxidants

Reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Flash Point(F) 
176 °F
Flash Point(C) 
80 °C
Protocols & Articles
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