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T15601 Aldrich

Tetrahydrothiophene

99%

Synonym: Tetramethylene sulfide, Thiolane, Thiophane

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Properties

Related Categories Building Blocks, C4 to C6, Chemical Synthesis, Heterocyclic Building Blocks, Thiophenes More...
vapor pressure   18 mmHg ( 25 °C)
assay   99%
refractive index   n20/D 1.504(lit.)
bp   119 °C(lit.)
mp   −96 °C(lit.)
density   1 g/mL at 25 °C(lit.)

Description

Packaging

5, 100, 500 g in glass bottle

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Precautionary statements 
Hazard Codes (Europe) 
Risk Statements (Europe) 
Safety Statements (Europe) 
16-23-36/37-61
RIDADR 
UN 2412 3 / PGII
WGK Germany 
2
RTECS 
XN0370000
Flash Point(F) 
55.4 °F
Flash Point(C) 
13 °C

Protocols & Articles

Peer-Reviewed Papers

References

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Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct. Mihaela Necula et al J. Biol. Chem. 282, 10311-24, (2007)

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Action of three ectopeptidases on corticotropin-releasing factor: metabolism and functional aspects. Ritchie JC, Davis TP, and Nemeroff CB Biol. Psychiatry 28(1), 22-33, (2003)

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[Hepatoprotective effect of thiophane in rats with experimental carbon tetrachloride-induced hepatitis]. Smol'iakova VI, Plotnikov MB, Chernysheva GA, et al. Eksp. Klin. Farmakol. 74(8), 37-40, (2011)

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[Pharmacological correction of the cytogenetic effects of cisplatin]. Voronova OL, Neupokoeva OV, Fedorova EP, et al. Eksp. Klin. Farmakol. 73(10), 37-9, (2010)

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[Hemorheological effects of thiophane on tetrachloromethane induced hepatic damage]. Smol'iakova VI, Plotnikov MB, Chernysheva GA, et al. Eksp. Klin. Farmakol. 73(8), 32-4, (2010)

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Targeting the proangiogenic VEGF-VEGFR protein-protein interface with drug-like compounds by in silico and in vitro screening. Gautier B, Miteva MA, Goncalves V, et al. Chem. Biol. 18(12), 1631-9, (2011)

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Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates. Tennstaedt A, et al. J. Biol. Chem. 287(25), 20931-41, (2012)

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Smell of danger: an analysis of LP-gas odorization. Cain WS and Turk A Am. Ind. Hyg. Assoc. J. 46(3), 115-26, (1985)

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Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Giulia Caron et al J. Med. Chem. 48, 3269-79, (2005)

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Dynorphin inhibits NEP activity in R1.1 mouse thymoma cells. Martin-Kleiner I, Balog T, and Marotti T Cell Biochem. Funct. 26(8), 916-9, (2008)

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The ganglionic blocking action of thiophanium derivatives. RANDALL LO, PETERSON WG, and LEHMANN G J. Pharmacol. Exp. Ther. 97(1), 48-57, (1949)

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Merck 14,9218

Beil. 17,V,1,36

Aldrich MSDS 1, 1672:D / Corp MSDS 1 (2), 3281:D / FT-IR 2 (1), 434:B / FT-IR 1 (1), 271:A / FT-NMR 1 (1), 434:A / IR-Spectra (3), 159:F / IR-Spectra (2), 142:H / NMR-Reference 2 (1), 232:D / RegBook 1 (1), 289:A / Structure Index 1, 40:A:2 / Vapor Phase 3, 356:A

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