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U6753 Aldrich

Ursolic acid

≥90%

Synonym: 3β-Hydroxy-12-ursen-28-ic acid

  • CAS Number 77-52-1

  • Empirical Formula (Hill Notation) C30H48O3

  • Molecular Weight 456.70

  •  Beilstein Registry Number 2228563

  •  EC Number 201-034-0

  •  MDL number MFCD00009621

  •  PubChem Substance ID 57654721

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Properties

Related Categories Asymmetric Synthesis, Cancer Research, Cell Biology, Chemical Synthesis, Chemopreventive Agents,
InChI Key   WCGUUGGRBIKTOS-GPOJBZKASA-N
assay   ≥90%
mp   292 °C (dec.)(lit.)
storage temp.   2-8°C
Gene Information   mouse ... Ifng(15978), Nos2(18126)

Description

Biochem/physiol Actions

Triterpenoid found in a variety of fruits, including apples. Cardioprotective and anti-tumor agent. Under study as a potential Alzheimer′s disease therapeutic due to its inhibitory effect on the interactions between amyloid-β and the CD36 receptor.

Packaging

100 mg in poly bottle

500 mg in poly tube

Application

UA has been used to study its possible protective role against kainate-induced excitotoxicity.

General description

Ursolic acid (UA) is a hydroxyl pentacyclic triterpenoic acid (HPTA), which exhibits anti-bacterial, anti-cancer, anti-oxidative and anti-inflammatory effects. It can also promote neuroregeneration after peripheral nerve injury. UA can enhance sleep duration by activating the GABAergic neurotransmitter system. [GABA= γ-aminobutyric acid]

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. U6753.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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