Cinnamaldehyde

Papers

Expanding the ChemGPS chemical space with natural products. Josefin Larsson et al J. Nat. Prod. 68, 985-91, (2005)

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Sensing with TRP channels. Thomas Voets et al Nat. Chem. Biol. 1, 85-92, (2005)

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Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Macpherson, L.J., et al. Nature, 1-4, (2007)

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Toward the development of chemoprevention agents. Part 1: Design, synthesis, and anti-inflammatory activities of a new class of 2,5-disubstituted-dioxacycloalkanes. Keli Gu et al Bioorg. Med. Chem. 15, 4775-99, (2007)

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4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Marcello Trevisani et al Proc. Natl. Acad. Sci. U. S. A. 104, 13519-24, (2007)

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Aldehydic components of cinnamon bark extract suppresses RANKL-induced osteoclastogenesis through NFATc1 downregulation. Kentaro Tsuji-Naito et al Bioorg. Med. Chem. 16, 9176-83, (2008)

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Potent inhibition of human phosphodiesterase-5 by icariin derivatives. Mario Dell'Agli et al J. Nat. Prod. 71, 1513-7, (2008)

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Tyrosinase-inhibitory constituents from the twigs of Cinnamomum cassia. Tran Minh Ngoc et al J. Nat. Prod. 72, 1205-8, (2009)

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Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents. Pier Giovanni Baraldi et al J. Med. Chem. 53, 5085-107, (2010)

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Oxime derivatives related to AP18: Agonists and antagonists of the TRPA1 receptor. Jeff Defalco et al Bioorg. Med. Chem. Lett. 20, 276-9, (2010)

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Contribution of cinnamic acid analogues in rosmarinic acid to inhibition of snake venom induced hemorrhage. Hnin Thanda Aung et al Bioorg. Med. Chem. 19, 2392-6, (2011)

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Novel dendrimeric lipopeptides with antifungal activity. Jolanta Janiszewska et al Bioorg. Med. Chem. Lett. 22, 1388-93, (2012)

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Discovery of estrogen receptor ? modulators from natural compounds in Si-Wu-Tang series decoctions using estrogen-responsive MCF-7 breast cancer cells. Li Liu et al Bioorg. Med. Chem. Lett. 22, 154-63, (2012)

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Merck 14,2297

Beil.,348

Arctander, 619 / Fenaroli, 299 / Sax 6, 795