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W302600 Aldrich

Sodium citrate dihydrate

≥99%, FG

Synonym: Citric acid trisodium salt dihydrate, Sodium citrate tribasic dihydrate, Trisodium citrate dihydrate



Related Categories Alphabetical Listings, Certified Food Grade Products, Flavors and Fragrances, Halal Certified Products, Kosher Certified Products,
biological source   synthetic
grade   FG
reg. compliance   EU Regulation 1333/2008 & 178/2002
  EU Regulation 178/2002
assay   ≥99%
mp   >300 °C(lit.)
Organoleptic   odorless
food allergen   no known allergens



1 kg in poly bottle

10, 25 kg in fiber drum

Other Notes

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Upgraded Fragrance Ingredients

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Protocols & Articles


Determination of Water Content in Trisodium citrate 2-hydrate Using Karl Fischer Titration

Carboxylic acid salts can be straightforwardly analyzed provided the sample dissolves rapidly in the working medium. Dissolution is accelerated by the addition of formamide, titration at elevated tem...
Keywords: Pharmaceutical, Titrations

Securing a Traceable Supply Chain for Food Grade Flavor Ingredients

Introduction Defining "Food Grade" Understanding "Food Grade" Versus "Industrial Grade" Top Questions to Ask a Flavor & Fragrances Supplier The Sigma-Aldrich Approach
Keywords: Food & Beverage, Food Safety, Solvents

Understanding the Complexities of Kosher Ingredients

Dr. Luke Grocholl, Quality Assurance Supervisor, Sigma-Aldrich Flavors & Fragrances and Rabbi Gershon Segal
Keywords: Fermentation, Food & Beverage, Safety industry

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Flavors and Fragrances Quality and Regulatory

From a comprehensive vendor approval process, to the testing of raw material at receipt as well as when product is ready to be shipped; we prove our dedication to supply chain transparency, every day.
Keywords: Food Safety

Peer-Reviewed Papers


Set your institution to view full text papers.

Substrate for citrate lyase (EC H.U. Bergmeyer, ed. Methods of Enzymatic Analysis 3rd ed., 2, 173, (1983)

A. Babb Artif. Organs 3, 470, (1979)

Anticoagulant. D.M. Ramsey J. Clin. Pathol. 30, 766, (1977)


Pen-on-paper approach toward the design of universal surface enhanced Raman scattering substrates. Polavarapu L, Porta AL, Novikov SM, et al. Small 10(15), 3065-71, (2014)


Nanoplasmonic biosensor: detection and amplification of dual bio-signatures of circulating tumor DNA. Nguyen AH, Sim SJ, et al. Biosens. Bioelectron. 67, 443-9, (2015)


Generation of induced pluripotent stem cells derived from primary and secondary myelofibrosis patient samples. Hosoi M, Kumano K, Taoka K, et al. Exp. Hematol. 42(9), 816-25, (2014)


Injectable colloidal gold in a sucrose acetate isobutyrate gelating matrix with potential use in radiation therapy. Jølck RI, Binderup T, Hansen AE, et al. Adv. Healthc. Mater. 3(10), 1680-7, (2014)


Stem cell-mediated delivery of SPIO-loaded gold nanoparticles for the theranosis of liver injury and hepatocellular carcinoma. Zhao J, Vykoukal J, Abdelsalam M, et al. Nanotechnology 25(40), 405101, (2014)


Affinity precipitation of a monoclonal antibody from an industrial harvest feedstock using an ELP-Z stimuli responsive biopolymer. Sheth RD, Jin M, Bhut BV, et al. Biotechnol. Bioeng. 111(8), 1595-603, (2014)


Atrial natriuretic peptide inhibits cell cycle activity of embryonic cardiac progenitor cells via its NPRA receptor signaling axis. Hotchkiss A, Feridooni T, Baguma-Nibasheka M, et al. Am. J. Physiol. Cell Physiol. 308(7), C557-69, (2015)


Enhancing optical forces on fluorescent up-converting nanoparticles by surface charge tailoring. Rodríguez-Rodríguez H, Rodríguez Sevilla P, Martín Rodríguez E, et al. Small 11(13), 1555-61, (2015)


Integrated analysis of transcriptomes of cancer cell lines and patient samples reveals STK11/LKB1-driven regulation of cAMP phosphodiesterase-4D. He N, Kim N, Song M, et al. Mol. Cancer Ther. 13(10), 2463-73, (2014)


Implantable hydrogel embedded dark-gold nanoswitch as a theranostic probe to sense and overcome cancer multidrug resistance. Conde J, Oliva N, Artzi N, et al. Proc. Natl. Acad. Sci. U. S. A. 112(11), E1278-87, (2015)


Effect of latent heat in boiling water on the synthesis of gold nanoparticles of different sizes by using the Turkevich method. Ding W, Zhang P, Li Y, et al. ChemPhysChem 16(2), 447-54, (2015)


Gold-promoted structurally ordered intermetallic palladium cobalt nanoparticles for the oxygen reduction reaction. Kuttiyiel KA, Sasaki K, Su D, et al. Nat. Commun. 5, 5185, (2014)


An endocytosis pathway initiated through neuropilin-1 and regulated by nutrient availability. Pang HB, Braun GB, Friman T, et al. Nat. Commun. 5, 4904, (2014)


Overview of a surface-ripened cheese community functioning by meta-omics analyses. Dugat-Bony E, Straub C, Teissandier A, et al. PLoS ONE 10(4), e0124360, (2015)


Alternative QuEChERS-based modular approach for pesticide residue analysis in food of animal origin. Lichtmannegger K, Fischer R, Steemann FX, et al. Anal. Bioanal. Chem 407(13), 3727-42, (2015)


pH-responsive, lysine-based hydrogels for the oral delivery of a wide size range of molecules. Watkins KA, Chen R, et al. Int. J. Pharm. 478(2), 496-503, (2015)


A novel label-free electrochemiluminescence aptasensor based on layered flowerlike molybdenum sulfide-graphene nanocomposites as matrix. Liu YM, Shi GF, Zhang JJ, et al. Colloids Surf. B Biointerfaces 122, 287-93, (2014)


Effect of silver nanoparticles on human mesenchymal stem cell differentiation. Sengstock C, Diendorf J, Epple M, et al. Beilstein J. Nanotechnol. 5, 2058-69, (2014)


Characterization of the physical stability of a lyophilized IgG1 mAb after accelerated shipping-like stress. Telikepalli S, Kumru OS, Kim JH, et al. J. Pharm. Sci. 104(2), 495-507, (2015)


Separation of porcine parvovirus from bovine serum albumin using PEG-salt aqueous two-phase system. Vijayaragavan KS, Zahid A, Young JW, et al. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967, 118-26, (2014)


Evaluation of gold nanoparticles toxicity towards human endothelial cells under static and flow conditions. Fede C, Fortunati I, Weber V, et al. Microvasc. Res. 97, 147-55, (2014)


A platelet P-selectin test predicts adverse cardiovascular events in patients with acute coronary syndromes treated with aspirin and clopidogrel. Thomas MR, Wijeyeratne YD, May JA, et al. Platelets 25(8), 612-8, (2014)


Differential proteomics study of platelets in asymptomatic constitutional macrothrombocytopenia: altered levels of cytoskeletal proteins. Karmakar S, Saha S, Banerjee D, et al. Eur. J. Haematol. 94(1), 43-50, (2015)


G-CSF displays restricted ability to promote Sca-1(+) cardiac stem cell proliferation in vitro. Luo H, Bassi G, Tessari M, et al. Mol. Cell Biochem. 397(1-2), 215-22, (2014)


Merck 14,8602

Beil. 3,IV,1272

Aldrich MSDS 1, 477:D / Arctander, 2852 / Corp MSDS 1 (1), 893:C / FT-IR 1 (1), 555:B / FT-IR 2 (1), 888:B / FT-NMR 1 (1), 860:A / IR-Spectra (2), 295:D / IR-Spectra (3), 330:B / RegBook 1 (1), 631:N / Sax 6, 2694 / Sigma FT-IR 1 (2), 403:A / Structure Index 1, 92:D:5

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