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W387509 Aldrich

Dimethyl sulfoxide

≥99%

Synonym: DMSO

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Properties

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biological source   synthetic
grade   Halal
vapor density   2.7 (vs air)
vapor pressure   0.42 mmHg ( 20 °C)
InChI Key   IAZDPXIOMUYVGZ-UHFFFAOYSA-N
assay   ≥99%
autoignition temp.   573 °F
shelf life   Expiration date period - 5 years
expl. lim.   42 %, 63 °F
color   colorless
refractive index   n20/D 1.479(lit.)
bp   189 °C(lit.)
  189 °C
mp   16-19 °C(lit.)
solubility   water: miscible
density   1.10 g/mL(lit.)
GMO content   GMO-free
Organoleptic   butter; sulfurous
food allergen   no known allergens

Description

Caution

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Application

DMSO has been used to prepare the DMSO-phosphate buffer solution, which was used to dissolve the selective ETB (ET = endothelin) receptor antagonist in a study. It has been used for the preparation of nysatin solution.

Dimethyl sulfoxide may be used in the synthesis of the following:
• α, β−Unsaturated carbonyl sugar derivatives.
• Conversion of secondary bromides or olefins to bromohydrin.
• Synthesis of α-hydroxycarbonyls from corresponding ketones.

General description

Dimethyl sulfoxide (DMSO) is a hygroscopic, high polarity amphiphilic solvent with an ability to dissolve many compounds. Cytotoxic study of DMSO on the pulp tissue repair-related activity of odontoblast-like cells showed it produced minor effects. Along with phosphorus pentaoxide it participates in the oxidation of carbohydrates to afford aldosuloses and aldosiduloses. DMSO participates in the oxidation of some partially-acetylated carbohydrates followed by elimination to afford unsaturated, derivatives. Solubility of amylose and amylopectin in DMSO has been evaluated.

Other Notes

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Protocols & Articles

Protocols

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Keywords: Sample preparations

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Peer-Reviewed Papers
15

References

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