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Z272302 Aldrich

Pharmacokinetics for the Pharmaceutical Scientist

  •  ISBN-10 1566760321

  •  ISBN-13 978-156676032-4

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Related Categories Books and Software, Labware, Pharmaceutical and Medicinal Chemistry Books More...
publication info   J. Wagner, Technomic Publishing Co., 1993, 336 pp., hard cover
mfr. no.   CRC Press

Description

General description

Major presentation of pharmacokinetics by a leading international expert. Methods for: estimating drug disposition parameters from data obtained after intravascular or extravascular drug administration, estimating rate and extent of drug bioavailability, and comparing rate and extent of drug availability following administration of several different dosage forms of a drug.

Table of Contents

Simple Linear Models
More Complicated Linear Models
Complicated Linear Models
Linear Multicompartment Disposition Parameters from Extravascular Downslope C,T Data
Noncompartmental and System Analysis Linear Multiple Dose Equations
Simple Nonlinear Models
More Complicated Nonlinear Models
Urinary Excretion
Absorption Analysis and Bioavailability
Physiological Pharmacokinetics
Relationship between Physiologically Based Flow Models and Usual Compartment Models
Protein Binding
Pharmacokinetic-Pharmacodynamic Modelling
Metabolic Kinetics
Laplace Derivation of Linear Pharmacokinetic Equations
Measures of Fit
Appendix
Index

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