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Z289469 Aldrich

Practice of Medicinal Chemistry

  •  ISBN-10 0127446400

  •  ISBN-13 978-012744640-0



publication info   C. Wermuth, ed., Academic Press, 1996, hard cover
mfr. no.   Elsevier


General description

This book collects in one single volume, the practical aspects of Medicinal Chemistry, seen from a chemical point of view, including the wealth of information which chemists accumulate over a career, but generally is never organized and presented in a coherent form in print. Emphasis is given to how medicinal chemists conduct their search for, and design of, new drug entities. In contrast to other books on the market, it focuses on the chemistry, rather than pharmacological concepts or description of the various therapeutic classes of drugs. It should become a standard reference on the tools available to medicinal chemists when designing new drugs.

Table of Contents

General Aspects of Medicinal Chemistry
Drug Targets and Lead Compound Discovery Strategies
Primary Exploration of Structure Activity Relationships
Spatial Organization, Receptor Mapping and Molecular Modeling
Chemical Modifications Influencing the Pharmacokinetic Properties
Pharmaceutical and Chemical Formulation Problems
Development of New Drugs: Legal and Economic Aspects
Subject Index

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