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00140585 Fluka

Isoquercitrin

primary pharmaceutical reference standard

Synonym: 3,3′,4′,5,7-Pentahydroxyflavone 3-β-glucoside, Isoquercitrin, Quercetin 3-β-D-glucoside

  • CAS Number 482-35-9

  • Empirical Formula (Hill Notation) C21H20O12

  • Molecular Weight 464.38

  •  Beilstein Registry Number 100989

  •  MDL number MFCD00017746

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Description

Application

Reference standard in the analysis of herbal medicinal products.

General description

Produced and qualified by HWI Analytik
Exact content by quantitative NMR can be found on the certificate

Price and Availability

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Safety & Documentation

Safety Information

WGK Germany 
3
RTECS 
DJ2982500

Documents

Certificate of Analysis

Protocols & Articles

Articles

Reference Standards for Herbal Medicinal Products

In collaborationwith HWI ANALYTIK, Sigma-Aldrich is launching a new product line of primary reference standards for use in the quality control, in-process control and stability testing of herbalmedic...
Matthias Nold
AnalytiX Volume 10 Article 1
Keywords: High performance liquid chromatography, Karl Fischer titrations, Nuclear magnetic resonance spectroscopy, PAGE, Pharmaceutical, Solvents, Titrations

Peer-Reviewed Papers

References

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Lessons learned from herbal medicinal products: the example of St. John's Wort (perpendicular). Adolf Nahrstedt et al J. Nat. Prod. 73, 1015-21, (2010)

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Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP). Anne Pick et al Bioorg. Med. Chem. 19, 2090-102, (2011)

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Inhibitory effects of polyphenols toward HCV from the mangrove plant Excoecaria agallocha L. Yongxin Li et al Bioorg. Med. Chem. Lett. 22, 1099-102, (2012)

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Construction of an Indonesian herbal constituents database and its use in Random Forest modelling in a search for inhibitors of aldose reductase. Sadaf Naeem et al Bioorg. Med. Chem. 20, 1251-8, (2012)

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Expanding the ChemGPS chemical space with natural products. Josefin Larsson et al J. Nat. Prod. 68, 985-91, (2005)

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Structure-activity relationship of human GLO I inhibitory natural flavonoids and their growth inhibitory effects. Ryoko Takasawa et al Bioorg. Med. Chem. 16, 3969-75, (2008)

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A new ursane-type triterpenoid glycoside from Centella asiatica leaves modulates the production of nitric oxide and secretion of TNF-? in activated RAW 264.7 cells. Nguyen Xuan Nhiem et al Bioorg. Med. Chem. Lett. 21, 1777-81, (2011)

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The selected flavonol glycoside derived from Sophorae Flos improves glucose uptake and inhibits adipocyte differentiation via activation AMPK in 3T3-L1 cells. Do Thi Ha et al Bioorg. Med. Chem. Lett. 20, 6076-81, (2010)

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Vanillic acid glycoside and quinic acid derivatives from Gardeniae Fructus. Hyoung Ja Kim et al J. Nat. Prod. 69, 600-3, (2006)

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Flavonoids as opioid receptor ligands: identification and preliminary structure-activity relationships. Peter L Katavic et al J. Nat. Prod. 70, 1278-82, (2007)

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Bioactive compounds from the fern Lepisorus contortus. Jian-Hong Yang et al J. Nat. Prod. 74, 129-36, (2011)

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The effect of flavonoid derivatives on doxorubicin transport and metabolism. Radka Václavíková et al Bioorg. Med. Chem. 16, 2034-42, (2008)

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Synthesis and antiviral activity of substituted quercetins Thapa, M., et al. Bioorg. Med. Chem. Lett. 22, 353-356, (2011)

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Isolation of quinic acid derivatives and flavonoids from the aerial parts of Lactuca indica L. and their hepatoprotective activity in vitro. Ki Hyun Kim et al Bioorg. Med. Chem. Lett. 17, 6739-43, (2007)

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Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids. Dragan Ami? et al Bioorg. Med. Chem. 18, 28-35, (2010)

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Studies on the chemical constituents and anticancer activity of Saxifraga stolonifera (L) Meeb. Zhuo Chen et al Bioorg. Med. Chem. 16, 1337-44, (2008)

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Alkaloids from the bark of Guatteria hispida and their evaluation as antioxidant and antimicrobial agents. Emmanoel Vilaça Costa et al J. Nat. Prod. 73, 1180-3, (2010)

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Phloroglucinol glycosides from the fresh fruits of Eucalyptus maideni. Li-Wen Tian et al J. Nat. Prod. 73, 160-3, (2010)

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Saponins and polyphenols from Fadogia ancylantha (makoni tea). Teresa Mencherini et al J. Nat. Prod. 73, 247-51, (2010)

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Antioxidant flavonoid glycosides from aerial parts of the fern Abacopteris penangiana. Zhongxiang Zhao et al J. Nat. Prod. 70, 1683-6, (2007)

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Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells. Hisashi Matsuda et al Bioorg. Med. Chem. 19, 2835-41, (2011)

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Constituents of Dalbergia sissoo Roxb. leaves with osteogenic activity. Preety Dixit et al Bioorg. Med. Chem. Lett. 22, 890-7, (2012)

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Anti-inflammatory, anti-tumor-promoting, and cytotoxic activities of constituents of marigold (Calendula officinalis) flowers. Motohiko Ukiya et al J. Nat. Prod. 69, 1692-6, (2006)

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Monoterpenoids from the aerial parts of Aruncus dioicus var. kamtschaticus and their antioxidant and cytotoxic activities. Su Yang Jeong et al Bioorg. Med. Chem. Lett. 21, 3252-6, (2011)

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Merck 14,5221

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