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05600 Fluka

Alizarin Red S

for microscopy (Hist.), indicator (pH 3.7-5.2)

Synonym: 3,4-Dihydroxy-9,10-dioxo-2-anthracenesulfonic acid sodium salt, Alizarin Carmine, Alizarin Red, water soluble, Alizarin sodium monosulfonate, Alizarin sulfonate sodium, Alizarinsulfonic acid sodium salt, Sodium alizarinsulfonate

  • CAS Number 130-22-3

  • Empirical Formula (Hill Notation) C14H7NaO7S

  • Molecular Weight 342.26

  •  Beilstein Registry Number 4117090

  •  Colour Index Number 58005

  •  EC Number 204-981-8

  •  MDL number MFCD00013049

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Description

Application

adsorption indicator

Other Notes

Reagent used for the spectrometric determination of hafnium(IV)1; Used for the pulspolarographic determination of gallium(III) and indium(III)2

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Safety & Documentation

Safety Information

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GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
WGK Germany 
3
RTECS 
CB1095300

Documents

Certificate of Analysis

Protocols & Articles

Peer-Reviewed Papers

References

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1. Z. Anal. Chem. 261, 42, (1972)

2. Z. Anal. Chem. 301, 203, (1980)

Transcription factor C/EBPbeta isoform ratio regulates osteoclastogenesis through MafB. Smink JJ EMBO J. 28(12), 1769-81, (2009)

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Biodentine induces immortalized murine pulp cell differentiation into odontoblast-like cells and stimulates biomineralization. Zanini M, Sautier JM, Berdal A, et al. J. Endod. 38(9), 1220-6, (2012)

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Adiponectin regulates functions of gingival fibroblasts and periodontal ligament cells. Iwayama T, Yanagita M, Mori K, et al. J. Periodont. Res. 47(5), 563-71, (2012)

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Genetic analysis of Hedgehog signaling in ventral body wall development and the onset of omphalocele formation. Matsumaru D PLoS ONE 6(1), e16260, (2011)

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Pathological features of oxalate nephrosis in a population of koalas (Phascolarctos cinereus) in South Australia. Speight KN, Boardman W, Breed WG, et al. Vet. Pathol. 50(2), 299-307, (2013)

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[Use of alizarin red S and alizarin complexone for immersion marking Sinocyclocheilus grahami]. Zhao YP, Pan XF, Yang JX, et al. Zool. Res. 34(5), 499-503, (2013)

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[The application of cobaltferous markers in serodiagnostic assay of infectious diseases]. Poltavchenko AG and Filatov PV Klin. Lab. Diagn. (11), 42-5, (2011)

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Beta-arrestin2 regulates parathyroid hormone effects on a p38 MAPK and NFkappaB gene expression network in osteoblasts. Bianchi EN Bone 45(4), 716-25, (2009)

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Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing. Scaffidi P Nat. Cell Biol. 10(4), 452-9, (2008)

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Humic acid facilitates the transport of ARS-labeled hydroxyapatite nanoparticles in iron oxyhydroxide-coated sand. Wang D, Bradford SA, Harvey RW, et al. Environ. Sci. Technol. 46(5), 2738-45, (2012)

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Effects of simvastain and enamel matrix derivative on Portland cement with bismuth oxide-induced growth and odontoblastic differentiation in human dental pulp cells. Lee SY, Min KS, Choi GW, et al. J. Endod. 38(3), 405-10, (2012)

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Elucidation of the mechanism of the reaction between phenylboronic acid and a model diol, Alizarin Red S. Tomsho JW and Benkovic SJ J. Org. Chem. 77(5), 2098-106, (2012)

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Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis. Zhang Q J. Immunol. 183(12), 7787-98, (2009)

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Effects of varied ionic calcium and phosphate on the proliferation, osteogenic differentiation and mineralization of human periodontal ligament cells in vitro. An S, Ling J, Gao Y, et al. J. Periodont. Res. 47(3), 374-82, (2012)

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Alizarin red S/copper ion-based ensemble for fluorescence turn on detection of glutathione with tunable dynamic range. Chen Z, Wang Z, Chen J, et al. Biosens. Bioelectron. 38(1), 202-8, (2012)

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Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development. Timothy J. Mead et al Proc. Natl. Acad. Sci. U. S. A. 106, 14420-5, (2009)

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Transport of ARS-labeled hydroxyapatite nanoparticles in saturated granular media is influenced by surface charge variability even in the presence of humic acid. Wang D, Bradford SA, Harvey RW, et al. J. Hazard. Mater. 229-230, 170-6, (2012)

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Histopathological evaluation of anterior lamellar corneal tissue-on/-off storage conditions on DSAEK donor tissue after storage in organ culture. Jhanji V, Pollock GA, Mackey AL, et al. Curr. Eye Res. 37(2), 155-8, (2012)

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Development of an all-in-one lentiviral vector system based on the original TetR for the easy generation of Tet-ON cell lines. Benabdellah K PLoS ONE 6(8), e23734, (2011)

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Oxygen tension regulates preosteocyte maturation and mineralization. Zahm, AM Bone 43(1), 25-31, (2008)

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Alternative visualization of SDS-PAGE separated phosphoproteins by alizarin red S-aluminum (III)-appended complex. Wang X, Hwang SY, Cong WT, et al. Electrophoresis 34(2), 235-43, (2013)

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Phytoceramides and acylated phytosterol glucosides from Pterospermum acerifolium Willd. seed coat and their osteogenic activity. Dixit P, Chand K, Khan MP, et al. Phytochemistry 81, 117-25, (2012)

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The antidiabetic effect of MSCs is not impaired by insulin prophylaxis and is not improved by a second dose of cells. Fernando Ezquer et al PLoS ONE 6, e16566, (2011)

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Osteogenic potential of human umbilical cord-derived mesenchymal stromal cells cultured with umbilical cord blood-derived autoserum. Baba K, Yamazaki Y, Ikemoto S, et al. J. Craniomaxillofac. Surg. 40(8), 768-72, (2012)

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Susceptibility of three strains of blue catfish, Ictalurus furcatus (Valenciennes), to Ichthyophthirius multifiliis. Xu DH, Klesius PH, Bosworth BG, et al. J. Fish Dis. 35(12), 887-95, (2012)

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Development and validation of sensitive spectrophotometric method for determination of two antiepileptics in pharmaceutical formulations. Gouda AA and Malah ZA Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 105, 488-96, (2013)

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Linear sweep voltammetric studies on the complex of alizarin red s with aloe polysaccharide and determination of aloe polysaccharide. Gu W, Wang Y, Wu T, et al. Carbohydr. Res. 349, 82-5, (2012)

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Effects of a calcium phosphate cement on mineralized nodule formation compared with endodontic cements. Ogata H, Hayashi M, Tsuda H, et al. Dent. Mater. J. 31(1), 92-7, (2012)

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Increased differentiation capacity of bone marrow-derived mesenchymal stem cells in aquaporin-5 deficiency. Yi F, Khan M, Gao H, et al. Stem Cells Dev. 21(13), 2495-507, (2012)

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Corticotomy-assisted orthodontic enhancement by bone morphogenetic protein-2 administration. Iglesias-Linares A, Yañez-Vico RM, Moreno-Fernandez AM, et al. J. Oral Maxillofac. Surg. 70(2), e124-32, (2012)

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Label-free fluorescence turn on detection of tiopronin with tunable dynamic range based on the ensemble of Alizarin Red S/copper ion. Chen Z, Wang Z, Chen J, et al. Talanta 99, 774-9, (2012)

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Low intensity pulsed ultrasound (LIPUS) influences the multilineage differentiation of mesenchymal stem and progenitor cell lines through ROCK-Cot/Tpl2-MEK-ERK signaling pathway. Kusuyama J, Bandow K, Shamoto M, et al. J. Biol. Chem. 289(15), 10330-44, (2014)

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The osteogenic study of tissue engineering bone with BMP2 and BMP7 gene-modified rat adipose-derived stem cell. Qing W, Guang-Xing C, Lin G, et al. J. Biomed. Biotechnol. 2012, 410879, (2012)

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Mathematical analysis of mandibular morphogenesis by micro-CT-based mouse and alizarin red S-stained-based human studies during development. Rafiq AM, Udagawa J, Lundh T, et al. Anat. Rec. (Hoboken.) 295(2), 313-27, (2012)

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Validation of otolith daily increments in early juveniles of shanny Lipophrys pholis. Carvalho MG, Moreira AS, Moreira C, et al. J. Fish Biol. 84(4), 1234-9, (2014)

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Evaluation of marking efficiency of different alizarin red S concentrations on body fish structures in Oreochromis niloticus (Perciformes: Cichlidae) juveniles. Ibáñez AL, Rodríguez-Canto A, Cortés-Martínez J, et al. Rev. Biol. Trop. 61(1), 193-201, (2013)

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Coupling technique of self-ordered ring and phosphorimetry for the determination of alkaline phosphatase and diseases prediction. Zhang LH, Zheng ZY, Jiang SL, et al. Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 97, 639-47, (2012)

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Influence of periosteal coverage on distraction osteogenesis with dental implant distractors. Yin X, Zhang C, Hze-Khoong EP, et al. J. Oral Maxillofac. Surg. 72(10), 1921-7, (2014)

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Merck 14,8573

Beil. 11,IV,683

FT-IR 2 (2), 3254:C / FT-IR 1 (2), 510:D / IR-Spectra (3), 1165:G / IR-Spectra (2), 1014:H / RegBook 1 (2), 2217:D / Sigma FT-IR 1 (2), 95:D / Stains and Dyes Ref, 80 / Structure Index 1, 348:C:2

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