12806 Fluka

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

≥97.0% (N)

Synonym: N,N,N′,N′-Tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborate, TBTU

  • CAS Number 125700-67-6

  • Linear Formula C11H16N5O · BF4

  • Molecular Weight 321.08

  •  Beilstein Registry Number 7066325

  •  MDL number MFCD00077413

  •  PubChem Substance ID 24847819

  • Popular Documents:  FTNMR (PDF)  


Related Categories Chemical Biology, Chemical Synthesis, Coupling, Peptide Chemistry, Peptide Coupling,
assay   ≥97.0% (N)
mp   205 °C (dec.)(lit.)
solubility   acetonitrile: soluble0.1 g/mL, clear, colorless
storage temp.   2-8°C



Coupling reagent which is ideally suited for solid-phase peptide synthesis.

Other Notes

Recent studies show that crystal as well as solution structure of this coupling agent is a guanidinium N-oxide and not an uronium compound1; Coupling reagent which is ideally suited for solid-phase peptide synthesis.2


1 kg in glass bottle

5, 25, 100, 250 g in glass bottle

Price and Availability

Suggested Laboratory Gloves

Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.

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