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44692 Fluka

Apigenin 7-glucoside

analytical standard

Synonym: Apigetrin, Cosmosiin

  • CAS Number 578-74-5

  • Empirical Formula (Hill Notation) C21H20O10

  • Molecular Weight 432.38

  •  Beilstein Registry Number 65669

  •  EC Number 209-430-5

  •  MDL number MFCD00016787

  •  PubChem Substance ID 24868305

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Apigenin 7-glucoside

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Safety Information

WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Peer-Reviewed Papers

References

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Antiproliferative and apoptotic effects of chamomile extract in various human cancer cells. Srivastava JK and Gupta S J. Agric. Food Chem. 55(23), 9470-8, (2007)

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Generation of stable reporter breast cancer cell lines for the identification of ER subtype selective ligands. Shanle EK, Hawse JR, and Xu W Biochem. Pharmacol. 82(12), 1940-9, (2011)

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Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP). Anne Pick et al Bioorg. Med. Chem. 19, 2090-102, (2011)

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Achillea millefolium L. s.l. -- is the anti-inflammatory activity mediated by protease inhibition? Benedek B, Kopp B, and Melzig MF J. Ethnopharmacol. 113(2), 312-7, (2007)

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CHMIS-C: a comprehensive herbal medicine information system for cancer. Xueliang Fang et al J. Med. Chem. 48, 1481-8, (2005)

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[Simultaneous determination of 6 active components in Chrysanthemum morifolium by HPLC]. Qin S and Wen X Zhongguo Zhong Yao Za Zhi 36(11), 1474-7, (2011)

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[Study on the flavonoids constituents of Trachelospermum jasminoides]. Tan XQ, Guo LJ, Chen HS, et al. Zhong Yao Cai 33(1), 58-60, (2010)

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[Studies on chemical constituents from Pteris multifida]. Wang WS, Wang ZQ, and Zhou YW Zhong Yao Cai 31(8), 1165-7, (2008)

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[Studies on chemical constituents in Huangjuhua (flowers of Chrysanthemum morifolium)]. Wang YJ, Yang XW, and Guo QS Zhongguo Zhong Yao Za Zhi 33(5), 526-30, (2008)

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Chemical constituents from the leaves of Broussonetia papyrifera. Feng WS, Li HW, Zheng XK, et al. Yao Xue Xue Bao 43(2), 173-80, (2008)

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[Studies on flavones in of Lavandula augustifolia]. Wu X, Liu J, Yu ZB, et al. Zhongguo Zhong Yao Za Zhi 32(9), 821-3, (2007)

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[Studies on chemical constituents of Acroptilon repens]. Zhao DB, Zhang W, Li MJ, et al. Zhongguo Zhong Yao Za Zhi 31(22), 1869-72, (2006)

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[Determination of main flavone glycosides in Flos Chrysanthemi and observation of factors influenced contents]. Hu BB, Wu ZS, Cai J, et al. Zhongguo Zhong Yao Za Zhi 31(21), 1772-5, (2006)

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Apigetrin induces erythroid differentiation of human leukemia cells K562: proteomics approach. Tsolmon S, Nakazaki E, Han J, et al. Mol. Nutr. Food. Res. 55 Suppl 1, S93-S102, (2011)

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Proteomic study of granulocytic differentiation induced by apigenin 7-glucoside in human promyelocytic leukemia HL-60 cells. Nakazaki E, Tsolmon S, Han J, et al. Eur. J. Nutr. 52(1), 25-35, (2013)

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Mesophyll distribution of 'antioxidant' flavonoid glycosides in Ligustrum vulgare leaves under contrasting sunlight irradiance. Agati G, Stefano G, Biricolti S, et al. Ann. Bot. 104(5), 853-61, (2009)

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Antioxidant and antigenotoxic properties of compounds isolated from Marrubium deserti de Noé. Zaabat N, Hay AE, Michalet S, et al. Food Chem. Toxicol. 49(12), 3328-35, (2011)

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Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids. Dragan Ami? et al Bioorg. Med. Chem. 18, 28-35, (2010)

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The bioavailability of apigenin-7-glucoside is influenced by human intestinal microbiota in rats. Hanske L, Loh G, Sczesny S, et al. J. Nutr. 139(6), 1095-102, (2009)

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Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities. Hyung Jae Jeong et al Bioorg. Med. Chem. 17, 6816-23, (2009)

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Solid-liquid transfer of biophenols from olive leaves for the enrichment of edible oils by a dynamic ultrasound-assisted approach. Japón-Luján R, Janeiro P, and Luque de Castro MD J. Agric. Food Chem. 56(16), 7231-5, (2008)

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Hexaconazole induces antioxidant protection and apigenin-7-glucoside accumulation in Matricaria chamomilla plants subjected to drought stress. Hojati M, Modarres-Sanavy SA, Ghanati F, et al. J. Plant Physiol. 168(8), 782-91, (2011)

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Antiestrogenic constituents of the Thai medicinal plants Capparis flavicans and Vitex glabrata. Prathan Luecha et al J. Nat. Prod. 72, 1954-9, (2009)

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Triterpenoids and flavonoids from celery (Apium graveolens). Kailan Zhou et al J. Nat. Prod. 72, 1563-7, (2009)

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LC determination of luteolin-7-O-β-D-glucoside and apigenin-7-O-β-D-glucoside in rat plasma after administration of Humulus scandens extract and its application to pharmacokinetic studies. Chen Z, Ying X, Meng S, et al. Nat. Prod. Res. 26(6), 530-9, (2012)

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Flavonoids from Dracocephalum tanguticum and their cardioprotective effects against doxorubicin-induced toxicity in H9c2 cells. Shu-Qi Wang et al Bioorg. Med. Chem. Lett. 20, 6411-5, (2010)

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Multivariate QSAR study on the antimutagenic activity of flavonoids against 3-NFA on Salmonella typhimurium TA98. Eduardo Borges de Melo et al Eur. J. Med. Chem. 45, 4562-9, (2010)

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Isolation of 3 flavonoids from Mentha longifolia (L.) Hudson subsp. longifolia and determination of their genotoxic potentials by using the E. coli WP2 test system. Baris O, Karadayi M, Yanmis D, et al. J. Food Sci. 76(9), T212-7, (2011)

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Secondary metabolites of Hypericum confertum and their possible chemotaxonomic significance. Cirak C, Radusiene J, Janulis V, et al. Nat. Prod. Commun. 5(6), 897-8, (2010)

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Chemical constituents from the seeds of Trifolium alexandrinum. Sharaf M Nat. Prod. Res. 22(18), 1620-3, (2008)

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Antioxidative activity of the flower of Torenia fournieri. Shindo K, Saito E, Sekiya M, et al. J. Nat. Med. 62(2), 247-8, (2008)

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High-performance liquid chromatographic determination and pharmacokinetic study of apigenin-7-O-β-D-glucoside in rat plasma after intravenous administration. Chen Z, Ying X, Meng S, et al. Arch. Pharm. Res. 34(5), 741-6, (2011)

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Flavonoid composition of Juniperus oblonga Bieb. Pisarev DI, Novikov OO, Novikova MY, et al. Bull. Exp. Biol. Med. 150(6), 714-7, (2011)

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Merck 14,731

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