Pyrroloquinoline quinone
≥97.0% (HPLC)
DOWNLOAD MSDS (PDF)Synonym:
4,5-
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CAS Number 72909-34-3
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Empirical Formula (Hill Notation) C14H6N2O8
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Molecular Weight 330.21
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Beilstein Registry Number 3596812
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MDL number MFCD00043125
Properties
| Related Categories | Biochemicals and Reagents, Cofactors, Enzymes, Inhibitors, and Substrates, Oxidation-Reduction |
| assay | ≥97.0% (HPLC) |
| impurities | ≤15% water |
| storage temp. | 2-8°C |
Description
Biochem/physiol Actions
PQQ is present in nanomolar quantities in most foods and in most animal tissuse. It promotes growth, mitochondrial function, and development in vivo and stimulates cell proliferation and viability in culture. It is a potent antioxidant that scavenges superoxide and peroxinitrite. It is neuroprotectant against 6-hydroxydopamine-induced and hypoxia/ischemia-induced neurotoxicity. PQQ conjugates to α-synuclein in vitro, inhibiting the formation of amyloid fibrils.
General description
Novel o-quinone coenzyme found in bacterial dehydrogenases and oxidases.
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