|Related Categories||Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antibiotics by Application, Antineoplastic and Immunosuppressive Antibiotics,|
Inhibitor of DNA synthesis, nuclear division, and cancer cells. Antibacterial to gram positive, gram negative, acid-fast bacilli.
Vial contains 2 mg mitomycin C and 48 mg NaCl (increases solubility).
Damage to cellular DNA is involved in mutagenesis and the development of cancer. The DNA in a human cell undergoes several thousand to a million damaging events per day, generated by both external (e...
BioFiles 2007, 2.4, 20.
Keywords: AGE, Alkylations, Apoptosis, Biochemistry, Cancer, Carcinogens, Catalysis, Clinical, DNA replication, Deaminations, Environmental, Gene expression, Metabolites, Methylations, Mutagens, Oxidations, Polymorphisms, Rearrangements, Recombination, Substitutions, Transcription
Endothelial cells in co-culture enhance embryonic stem cell differentiation to pancreatic progenitors and insulin-producing cells through BMP signaling. Talavera-Adame D, Wu G, He Y, et al. Stem Cell Rev. 7(3), 532-43, (2011)
Circulating tumor markers: predictors of incomplete cytoreduction and powerful determinants of outcome in pseudomyxoma peritonei. Kusamura S, Hutanu I, Baratti D, et al. J. Surg. Oncol. 108(1), 1-8, (2013)
Phase III randomised controlled trial of neoadjuvant chemotherapy plus radical surgery vs radical surgery alone for stages IB2, IIA2, and IIB cervical cancer: a Japan Clinical Oncology Group trial (JCOG 0102). Katsumata N, Yoshikawa H, Kobayashi H, et al. Br. J. Cancer 108(10), 1957-63, (2013)
[Concurrent radiochemotherapy with 5-FU/mitomycin remains standard treatment for anal carcinoma. Long-term results of the phase III RTOG 98-11 trial]. Nieder C Strahlenther. Onkol. 189(6), 512-3, (2013)
Simultaneous integrated boost-intensity modulated radiation therapy with concomitant capecitabine and mitomycin C for locally advanced anal carcinoma: a phase 1 study. Deenen MJ, Dewit L, Boot H, et al. Int. J. Radiat. Oncol. Biol. Phys. 85(5), e201-7, (2013)
Inhibition of epidural fibrosis after microendoscopic discectomy with topical application of mitomycin C: a randomized, controlled, double-blind trial. Liu L, Sui T, Hong X, et al. J. Neurosurg. Spine 18(5), 421-7, (2013)
Outcome of recurrent pterygium with intraoperative 0.02% mitomycin C and free flap limbal conjunctival autograft. Narsani AK, Nagdev PR, and Memon MN J. Coll. Physicians Surg. Pak. 23(3), 199-202, (2013)
Mitomycin-C and capecitabine (MIXE) as salvage treatment in patients with refractory metastatic colorectal cancer: a retrospective study. Saif MW, Kaley K, Brennan M, et al. Anticancer Res. 33(6), 2743-6, (2013)
Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2 × 2 factorial trial. James RD, Glynne-Jones R, Meadows HM, et al. Lancet Oncol. 14(6), 516-24, (2013)
Adjuvant chemotherapy for gastric cancer: a randomised phase 3 trial of mitomycin-C plus either short-term doxifluridine or long-term doxifluridine plus cisplatin after curative D2 gastrectomy (AMC0201). Kang YK, Chang HM, Yook JH, et al. Br. J. Cancer 108(6), 1245-51, (2013)
The investigation of a traditional Chinese medicine, Guizhi Fuling Wan (GFW) as an intravesical therapeutic agent for urothelial carcinoma of the bladder. Lu CC, Lin MY, Chen SY, et al. BMC Complement Altern. Med. 13, 44, (2013)
Epidermal growth factor receptor expression as prognostic marker in patients with anal carcinoma treated with concurrent chemoradiation therapy. Fraunholz I, Rödel F, Kohler D, et al. Int. J. Radiat. Oncol. Biol. Phys. 86(5), 901-7, (2013)
Molecular analysis of the inhibitory effect of N-acetyl-L-cysteine on the proliferation and invasiveness of pancreatic cancer cells. Mezencev R, Wang L, Xu W, et al. Anticancer Drugs 24(5), 504-18, (2013)
Immunotoxin targeting EpCAM effectively inhibits peritoneal tumor growth in experimental models of mucinous peritoneal surface malignancies. Flatmark K, Guldvik IJ, Svensson H, et al. Int. J. Cancer 133(6), 1497-506, (2013)
ICE Afe 1, an actively excising genetic element from the biomining bacterium Acidithiobacillus ferrooxidans. Bustamante P, Covarrubias PC, Levicán G, et al. J. Mol. Microbiol. Biotechnol. 22(6), 399-407, (2012)
Y. Hashimoto et al. Acc. Chem. Res. 17, 403, (1984)
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