|Related Categories||Biochemicals and Reagents, Detection, Fluorescent Indicators and Probes, Fluorescent Labels, Fluorescent Probes, Labels, Particles and Stains,|
|fluorescence||λex 380 nm; λem 461 nm in methanol|
|λex 390 nm; λem 478 nm in 0.1 M phosphate pH 7.5 (after derivatization with glutathione)|
|suitability||suitable for fluorescence|
Cell-permeant probe for quantifying glutathione levels in cells.1 Suitable for the detection of thiol-groups.
Contains up to 15% of an isomer (NMR)
Bottomless glass bottle. Contents are inside inserted fused cone.
|Precautionary statements||P261-P305 + P351 + P338|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Gloves|
|Hazard Codes (Europe)||Xi|
|Risk Statements (Europe)||36/37/38|
|Safety Statements (Europe)||26-36|
Increased intracellular H₂O₂ availability preferentially drives glutathione accumulation in vacuoles and chloroplasts. Queval G, Jaillard D, Zechmann B, et al. Plant Cell Environ. 34(1), 21-32, (2011)
The antioxidant glutathione in the fish cell lines EPC and BCF-2: response to model pro-oxidants as measured by three different fluorescent dyes. Jos A, Cameán AM, Pflugmacher S, et al. Toxicol. In Vitro 23(3), 546-53, (2009)
How plants cope with foreign compounds. Translocation of xenobiotic glutathione conjugates in roots of barley (Hordeum vulgare). Schröder P, Scheer CE, Diekmann F, et al. Environ. Sci. Pollut. Res. Int. 14(2), 114-22, (2007)
Subcellular localization and possible functions of gamma-glutamyltransferase in the radish (Raphanus sativus L.) plant. Nakano Y, Okawa S, Prieto R, et al. Biosci. Biotechnol. Biochem. 70(7), 1790-3, (2006)
Use of flow cytometry and monochlorobimane to quantitate intracellular glutathione concentrations in feline leukocytes. Webb C, Bedwell C, Guth A, et al. Vet. Immunol. Immunopathol. 112(3-4), 129-40, (2006)
Measurement of the intracellular distribution of reduced glutathione in cultured rat hepatocytes using monochlorobimane and confocal laser scanning microscopy. Stevenson D, Wokosin D, Girkin J, et al. Toxicol. In Vitro 16(5), 609-19, (2002)
Vacuolar sequestration of glutathione S-conjugates outcompetes a possible degradation of the glutathione moiety by phytochelatin synthase. Grzam A, Tennstedt P, Clemens S, et al. FEBS Lett. 580(27), 6384-90, (2006)
Evaluation of fluorescent dyes for measuring intracellular glutathione content in primary cultures of human neurons and neuroblastoma SH-SY5Y. Sebastià J, Cristòfol R, Martín M, et al. Cytometry. A 51(1), 16-25, (2003)
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