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74856 Fluka

(−)-Linalool

analytical standard

Synonym: (R)-(−)-3,7-Dimethyl-1,6-octadien-3-ol

  • CAS Number 126-91-0

  • Linear Formula (CH3)2C=CHCH2CH2C(CH3)(OH)CH=CH2

  • Molecular Weight 154.25

  •  Beilstein Registry Number 1721487

  •  EC Number 204-811-2

  •  MDL number MFCD00135469

  •  PubChem Substance ID 24886737

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Hazard Codes (Europe) 
Xi
Risk Statements (Europe) 
Safety Statements (Europe) 
26-36/37
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
RTECS 
RG5800000
Flash Point(F) 
168.8 °F
Flash Point(C) 
76 °C

Protocols & Articles

Related Content

Flavor and Fragrance Analysis

It’s all about your workflow. Sample preparation, separation, detection and analysis. Speed and resolution is key in determining purity or verifying composition.
Keywords: Calorimetry, Gas chromatography, Mass spectrometry, Sample preparations, Separation

Reliable Identification of F&F Components by GC/MS and Linear Retention Indices and Multidimensional Chromatography [VIDEO]

In this on-demand webinar by Prof. Luigi Mondello of the University of Messina, Italy, highlights the shortcomings of GC/MS analysis in the identification of F&F compounds when using a straightforwar...
Keywords: Chromatography, Gas chromatography, High performance liquid chromatography, Mass spectrometry

Peer-Reviewed Papers

References

Set your institution to view full text papers.

A toxicologic and dermatologic assessment of linalool and related esters when used as fragrance ingredients. Bickers D, Calow P, Greim H, et al. Food Chem. Toxicol. 41(7), 919-42, (2003)

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Aroma profiles and preferences of Jasminum sambac L. flowers grown in Thailand. Kanlayavattanakul M, Kitsiripaisarn S, and Lourith N J. Cosmet. Sci. 64(6), 483-93, (2013)

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Assessment of the acaricidal activity of carvacrol, (E)-cinnamaldehyde, trans-anethole, and linalool on larvae of Rhipicephalus microplus and Dermacentor nitens (Acari: Ixodidae). de Oliveira Souza Senra T, Zeringóta V, de Oliveira Monteiro CM, et al. Parasitol. Res. 112(4), 1461-6, (2013)

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[Study on the chemical components, antimicrobial and antitumor activities of the essential oil from the leaves of Zanthoxylum avicennae]. Zhang DS, Zhong QX, Song XM, et al. Zhong Yao Cai 35(8), 1263-7, (2012)

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Air-oxidized linalool: a frequent cause of fragrance contact allergy. Bråred Christensson J, Andersen KE, Bruze M, et al. Contact Dermatitis 67(5), 247-59, (2012)

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The early bee catches the flower - circadian rhythmicity influences learning performance in honey bees, Apis mellifera Marina Lehmann et al Behav. Ecol. Sociobiol. 65, 205-215, (2010)

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Specific herbivore-induced volatiles defend plants and determine insect community composition in the field. Xiao Y, Wang Q, Erb M, et al. Ecol. Lett. 15(10), 1130-9, (2012)

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Potential source of S-(+)-linalool from Cinnamomum osmophloeum ct. linalool leaf: essential oil profile and enantiomeric purity. Cheng BH, Lin CY, Yeh TF, et al. J. Agric. Food Chem. 60(31), 7623-8, (2012)

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Antidepressant activity of Litsea glaucescens essential oil: identification of β-pinene and linalool as active principles. Guzmán-Gutiérrez SL, Gómez-Cansino R, García-Zebadúa JC, et al. J. Ethnopharmacol. 143(2), 673-9, (2012)

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Functional genomics reveals that a compact terpene synthase gene family can account for terpene volatile production in apple. Nieuwenhuizen NJ, Green SA, Chen X, et al. Plant Physiol. 161(2), 787-804, (2013)

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In vitro neuropeptide Y mRNA expressing model for screening essences that may affect appetite using Rolf B1.T cells. Chen SW, Wu PJ, and Chiang BH J. Agric. Food Chem. 60(32), 7824-9, (2012)

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Fragrance material review on linalool. Letizia CS, Cocchiara J, Lalko J, et al. Food Chem. Toxicol. 41(7), 943-64, (2003)

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Anti-inflammatory effects of linalool in RAW 264.7 macrophages and lipopolysaccharide-induced lung injury model. Huo M, Cui X, Xue J, et al. J. Surg. Res. 180(1), e47-54, (2013)

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Environmental and seasonal influences on red raspberry flavour volatiles and identification of quantitative trait loci (QTL) and candidate genes. Paterson A, Kassim A, McCallum S, et al. Theor. Appl. Genet. 126(1), 33-48, (2013)

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Chemical composition, olfactory analysis and antibacterial activity of Thymus vulgaris chemotypes geraniol, 4-thujanol/terpinen-4-ol, thymol and linalool cultivated in southern France. Schmidt E, Wanner J, Hiiferl M, et al. Nat. Prod. Commun. 7(8), 1095-8, (2012)

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Effect of linalool as a component of Humulus lupulus on doxorubicin-induced antitumor activity. Miyashita M and Sadzuka Y Food Chem. Toxicol. 53, 174-9, (2013)

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Monitoring of biotransformation of hop aroma compounds in an in vitro digestion model. Heinlein A and Buettner A Food Funct. 3(10), 1059-67, (2012)

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Species-specific effects of herbivory on the oviposition behavior of the moth Manduca sexta. Reisenman CE, Riffell JA, Duffy K, et al. J. Chem. Ecol. 39(1), 76-89, (2013)

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Chemical composition, antioxidant, and antimicrobial activities of essential oil from pine needle (Cedrus deodara). Zeng WC, Zhang Z, Gao H, et al. J. Food Sci. 77(7), C824-9, (2012)

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Volatiles from apple trees infested with light brown apple moth larvae attract the parasitoid Dolichogenidia tasmanica. Suckling DM, Twidle AM, Gibb AR, et al. J. Agric. Food Chem. 60(38), 9562-6, (2012)

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An investigation on the chemotactic responses of different entomopathogenic nematode strains to mechanically damaged maize root volatile compounds. Laznik Z and Trdan S Exp. Parasitol. 134(3), 349-55, (2013)

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Toxicology of selected pesticides, drugs, and chemicals. D-limonene, linalool, and crude citrus oil extracts. Hooser SB Vet. Clin. North Am. Small Anim. Pract. 20(2), 383-5, (1990)

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Characterization of aroma compounds in Chinese bayberry (Myrica rubra Sieb. et Zucc.) by gas chromatography mass spectrometry (GC-MS) and olfactometry (GC-O). Kang W, Li Y, Xu Y, et al. J. Food Sci. 77(10), C1030-5, (2012)

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α-Linalool - a marker compound of forged/synthetic sweet basil (Ocimum basilicum L.) essential oils. Radulović NS, Blagojević PD, and Miltojević AB J. Sci. Food Agric. 93(13), 3292-303, (2013)

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Addendum to Fragrance material review on linalool. Lapczynski A, Letizia CS, and Api AM Food Chem. Toxicol. 46 Suppl 11, S190-2, (2008)

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β-Cyclodextrin-complexed (-)-linalool produces antinociceptive effect superior to that of (-)-linalool in experimental pain protocols. Quintans-Júnior LJ, Barreto RS, Menezes PP, et al. Basic Clin Pharmacol Toxicol. 113(3), 167-72, (2013)

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Isolation and biological activities of decanal, linalool, valencene, and octanal from sweet orange oil. Liu K, Chen Q, Liu Y, et al. J. Food Sci. 77(11), C1156-61, (2012)

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Season's variation impact on Citrus aurantium leaves essential oil: chemical composition and biological activities. Ellouze I, Abderrabba M, Sabaou N, et al. J. Food Sci. 77(9), T173-80, (2012)

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Myrtus communis L. infusions: the effect of infusion time on phytochemical composition, antioxidant, and antimicrobial activities. Messaoud C, Laabidi A, and Boussaid M J. Food Sci. 77(9), C941-7, (2012)

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Fragrance material review on l-linalool. Lapczynski A, Bhatia SP, Letizia CS, et al. Food Chem. Toxicol. 46 Suppl 11, S195-6, (2008)

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Fragrance material review on d-linalool. Lapczynski A, Letizia CS, and Api AM Food Chem. Toxicol. 46 Suppl 11, S193-4, (2008)

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Influence of yeast mannoproteins in the aroma improvement of white wines. Juega M, Nunez YP, Carrascosa AV, et al. J. Food Sci. 77(8), M499-504, (2012)

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Physical and psychologic effects of aromatherapy inhalation on pregnant women: a randomized controlled trial. Igarashi T J. Altern. Complement. Med. 19(10), 805-10, (2013)

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Intraplantar injection of linalool reduces paclitaxel-induced acute pain in mice. Katsuyama S, Kuwahata H, Yagi T, et al. Biomed. Res. 33(3), 175-81, (2012)

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Cardiovascular effects induced by linalool in normotensive and hypertensive rats. Anjos PJ, Lima AO, Cunha PS, et al. Z. Naturforsch. C 68(5-6), 181-90, (2013)

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Relationship between mood change, odour and its physiological effects in humans while inhaling the fragrances of essential oils as well as linalool and its enantiomers. Sugawara Y, Shigetho A, Yoneda M, et al. Molecules 18(3), 3312-38, (2013)

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Synergistic antiproliferative and anticholesterogenic effects of linalool, 1,8-cineole, and simvastatin on human cell lines. Rodenak Kladniew B, Polo M, Montero Villegas S, et al. Chem. Biol. Interact. 214, 57-68, (2014)

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Beil. 1,IV,2270

Arctander, 1803 / FT-IR 1 (1), 148:C

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