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81845 Fluka

Propidium iodide

≥94% (HPLC)

Synonym: 3,8-Diamino-5-[3-(diethylmethylammonio)propyl]-6-phenylphenanthridinium diiodide

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Description

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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TruPAGE™ Pre-cast Polyacrylamide Gels


TruPAGE™ Pre-cast Polyacrylamide GelsTruPAGE Gels run true every time!

  • . 2-Year Shelf Life
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  • . Higher Capacity Wells



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Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
Hazard Codes (Europe) 
Xn
Risk Statements (Europe) 
Safety Statements (Europe) 
26-36/37
WGK Germany 
3
RTECS 
SF7949600

Protocols & Articles

Articles

Discover Bioactive Small Molecules for Apoptosis

Apoptosis, or programmed cell death (PCD), is a selective process for the removal of unnecessary, infected or transformed cells in various biological systems. As it plays a role in the homeostasis of...
Keywords: Apoptosis, Bioactive small molecules, Cancer, Clinical, Diseases, Ligands, Neurodegenerative Diseases

Peer-Reviewed Papers

References

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Dopamine D2 Receptor Activity Modulates Akt Signaling And Alters GABAergic Neuron Development And Motor Behavior In Zebrafish Larvae. Souza, B.R., et al. J. Neurosci. 31, 5512-25, (2011)

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Reagent for the fluorescent staining of nucleic acids. J. Tas, G. Westerneng J. Histochem. Cytochem. 29, 929, (1981)

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Features of apoptotic cells measured by flow cytometry. Darzynkiewicz, Z., et al. Cytometry 13, 795-808, (1992)

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ERK- And Akt-dependent Neuroprotection By Erythropoietin (EPO) Against Glyoxal-AGEs Via Modulation Of Bcl-xL, Bax, And BAD. Shen, J., et al. Invest. Ophthalmol. Vis. Sci. 51, 35-46, (2010)

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Dead Cell Counts During Serum Cultivation Are Underestimated By The Fluorescent Live/dead Assay. Zhou, S., et al. Biotechnol. J. 6, 513-8, (2011)

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Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma. Saha, MN PLoS ONE 7(1), e30215, (2012)

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Farnesol-induced apoptosis in Candida albicans. Mark E. Shirtliff et al Antimicrob. Agents Chemother. 53, 2392-401, (2009)

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PLC-gamma2 is essential for formation and maintenance of memory B cells. Hikida M J. Exp. Med. 206(3), 681-9, (2009)

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Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death. Roxane Simeone et al PLoS Pathog. 8, e1002507, (2012)

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The E3 ubiquitin ligase c-Cbl restricts development and functions of hematopoietic stem cells. Rathinam C Genes Dev. 22(8), 992-7, (2008)

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Tubulin polymerization promoting protein 1 (Tppp1) phosphorylation by Rho-associated coiled-coil kinase (rock) and cyclin-dependent kinase 1 (Cdk1) inhibits microtubule dynamics to increase cell proliferation. Schofield AV, Gamell C, Suryadinata R, et al. J. Biol. Chem. 288(11), 7907-17, (2013)

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Discrimination of viable from non-viable gram-negative bacterial pathogens in airborne particles using propidium monoazide-assisted qPCR. Kaushik R and Balasubramanian R Sci. Total Environ. 449, 237-43, (2013)

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Multiple cellular mechanisms related to cyclin A1 in prostate cancer invasion and metastasis. Wegiel B J. Natl. Cancer Inst. 100(14), 1022-36, (2008)

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The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate. Blanco S, Kurowski A, Nichols J, et al. PLoS Genet. 7(12), e1002403, (2011)

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γ-Radiation promotes immunological recognition of cancer cells through increased expression of cancer-testis antigens in vitro and in vivo. Sharma A, Bode B, Wenger RH, et al. PLoS ONE 6(11), e28217, (2011)

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PTEN loss promotes mitochondrially dependent type II Fas-induced apoptosis via PEA-15. Peacock JW, Palmer J, Fink D, et al. Mol. Cell. Biol. 29(5), 1222-34, (2009)

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CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes. He H, Yu FX, Sun C, et al. PLoS ONE 6(7), e22088, (2011)

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Guggulsterone targets smokeless tobacco induced PI3K/Akt pathway in head and neck cancer cells. Muzafar A. Macha et al PLoS ONE 6, e14728, (2011)

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Protein kinase C-dependent phosphorylation regulates the cell cycle-inhibitory function of the p73 carboxy terminus transactivation domain. Nyman U Mol. Cell. Biol. 29(7), 1814-25, (2009)

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The novel p53 target gene IRF2BP2 participates in cell survival during the p53 stress response. Koeppel M Nucleic Acids Res. 37(2), 322-35, (2009)

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miR-181a regulates cap-dependent translation of p27(kip1) mRNA in myeloid cells. Cuesta R, Martínez-Sánchez A, and Gebauer F Mol. Cell. Biol. 29(10), 2841-51, (2009)

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Novel roles of hakai in cell proliferation and oncogenesis. Figueroa A Mol. Biol. Cell 20(15), 3533-42, (2009)

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Adult AIDS-like disease in a novel inducible human immunodeficiency virus type 1 Nef transgenic mouse model: CD4+ T-cell activation is Nef dependent and can occur in the absence of lymphophenia. Rahim MM J. Virol. 83(22), 11830-46, (2009)

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Diversity in genomic organisation, developmental regulation and distribution of the murine PR72/B" subunits of protein phosphatase 2A. Karen Zwaenepoel et al BMC Genomics 9, 393, (2008)

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Astrocyte-derived tissue transglutaminase interacts with fibronectin: a role in astrocyte adhesion and migration? van Strien ME PLoS ONE 6(9), e25037, (2011)

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[Comparison of 2 techniques for measuring lymphocyte proliferation: tritiated methyl-thymidine incorporation and propidium iodide fluorometry]. Brohee D, Vanhaeverbeek M, Kennes B, et al. Rev. Med. Brux. 16(5), 368-71, (1995)

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Piceatannol exhibits selective toxicity to multiple myeloma cells and influences the Wnt/ beta-catenin pathway. Schmeel FC, Schmeel LC, Kim Y, et al. Hematol. Oncol. 32(4), 197-204, (2014)

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Fluorescence-activated cell sorting-based quantitation of T cell receptor restimulation-induced cell death in activated, primary human T cells. Katz G and Snow AL Methods Mol. Biol. 979, 15-23, (2013)

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Cell death in the skin: how to study its quality and quantity? Makarov R, Geserick P, Feoktistova M, et al. Methods Mol. Biol. 961, 201-18, (2013)

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Cell apoptosis induced by hookworm antigens: a strategy of immunomodulation. Gazzinelli-Guimarães PH, Souza-Fagundes EM, Cancado GG, et al. Front. Biosci. (Elite Ed.) 5, 662-75, (2013)

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Recovery and Biodistribution of Ex Vivo Expanded Human Erythroblasts Injected into NOD/SCID/IL2Rγ mice. Ghinassi B, Ferro L, Masiello F, et al. Stem Cells Int. 2011, 673752, (2011)

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Inhibition of Human Cervical Cancer Cell Growth by Ethanolic Extract of Boerhaavia diffusa Linn. (Punarnava) Root. Srivastava R Evid. Based. Complement. Alternat. Med. 2011, 427031, (2011)

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Induction and flow cytometry identification of tetraploids from seed-derived explants through colchicine treatments in Catharanthus roseus (L.) G. Don. Xing SH J. Biomed. Biotechnol. 2011, 793198, (2011)

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Regulated expression of CCL21 in the prostate tumor microenvironment inhibits tumor growth and metastasis in an orthotopic model of prostate cancer. Nazita Yousefieh et al Cancer Microenviron. 2, 59-67, (2009)

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Application of a haematopoetic progenitor cell-targeted adeno-associated viral (AAV) vector established by selection of an AAV random peptide library on a leukaemia cell line. Stiefelhagen M, Sellner L, Kleinschmidt JA, et al. Genet. Vaccines Ther. 6, 12, (2008)

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The use of propidium iodide to assess excitotoxic neuronal death in primary mixed cortical cultures. Lau AC, Cui H, and Tymianski M Methods Mol. Biol. 399, 15-29, (2007)

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MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappaB activation in human pancreatic islet cells. Mokhtari D Diabetes 57(7), 1896-904, (2008)

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Induction of mitochondrial biogenesis protects against caspase-dependent and caspase-independent apoptosis in L6 myoblasts. Dam AD, Mitchell AS, and Quadrilatero J Biochim. Biophys. Acta 1833(12), 3426-35, (2013)

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HMGB1 mediates endogenous TLR2 activation and brain tumor regression. Curtin JF PLoS Med. 6(1), e10, (2009)

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Magnetic nano-beads based separation combined with propidium monoazide treatment and multiplex PCR assay for simultaneous detection of viable Salmonella Typhimurium, Escherichia coli O157:H7 and Listeria monocytogenes in food products. Yang Y, Xu F, Xu H, et al. Food Microbiol. 34(2), 418-24, (2013)

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Rhinovirus disrupts the barrier function of polarized airway epithelial cells. Sajjan U Am. J. Respir. Crit. Care Med. 178(12), 1271-81, (2008)

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Propidium monoazide does not fully inhibit the detection of dead Campylobacter on broiler chicken carcasses by qPCR. Pacholewicz E, Swart A, Lipman LJ, et al. J. Microbiol. Methods 95(1), 32-8, (2013)

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Zebrafish miR-1 and miR-133 shape muscle gene expression and regulate sarcomeric actin organization. Mishima Y Genes Dev. 23(5), 619-32, (2009)

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Role of vitamin D receptor in the antiproliferative effects of calcitriol in tumor-derived endothelial cells and tumor angiogenesis in vivo. Ivy Chung et al Cancer Res. 69, 967-75, (2008)

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The neuronal microRNA miR-326 acts in a feedback loop with notch and has therapeutic potential against brain tumors. Kefas B J. Neurosci. 29(48), 15161-8, (2009)

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Bone marrow-derived cells from male donors do not contribute to the endometrial side population of the recipient. Cervelló I, Gil-Sanchis C, Mas A, et al. PLoS ONE 7(1), e30260, (2012)

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Involvement of cyclin B1 in progesterone-mediated cell growth inhibition, G2/M cell cycle arrest, and apoptosis in human endometrial cell. Tang L Reprod. Biol. Endocrinol. 7, 144, (2009)

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Nuclear entry of hyperbranched polylysine nanoparticles into cochlear cells. Weikai Zhang et al Int. J. Nanomedicine 6, 535-46, (2011)

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miR-34a regulates mouse neural stem cell differentiation. Márcia M. Aranha et al PLoS ONE 6, e21396, (2011)

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The shedding of CD62L (L-selectin) regulates the acquisition of lytic activity in human tumor reactive T lymphocytes. Yang S, Liu F, Wang QJ, et al. PLoS ONE 6(7), e22560, (2011)

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Reconstruction of endometrium from human endometrial side population cell lines. Cervelló I, Mas A, Gil-Sanchis C, et al. PLoS ONE 6(6), e21221, (2011)

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Inhibition of phosphatidylinositol 3-kinase signaling in hepatic stellate cells blocks the progression of hepatic fibrosis. Son G Hepatology 50(5), 1512-23, (2009)

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Novel DNA microarray system for analysis of nascent mRNAs. Masaya Ohtsu et al DNA Research 15, 241-51, (2008)

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Aberrant expression of nucleostemin activates p53 and induces cell cycle arrest via inhibition of MDM2. Dai MS Mol. Cell. Biol. 28(13), 4365-76, (2008)

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EZH2 depletion blocks the proliferation of colon cancer cells. Fussbroich B, Wagener N, Macher-Goeppinger S, et al. PLoS ONE 6(7), e21651, (2011)

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Effect of 5-aminolevulinic acid-based photodynamic therapy via reactive oxygen species in human cholangiocarcinoma cells. Cy Hyun Kim et al Int. J. Nanomedicine 6, 1357-63, (2011)

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Cellular players and role of selectin ligands in leukocyte recruitment in a T-cell-initiated delayed-type hypersensitivity reaction. Doebis C Am. J. Pathol. 173(4), 1067-76, (2008)

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Endothelial progenitor cell number and colony-forming capacity in overweight and obese adults. MacEneaney OJ Int. J. Obes. 33(2), 219-25, (2009)

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Nerve growth factor and its receptor TrkA serve as potential markers for human corneal epithelial progenitor cells. Qi H Exp. Eye Res. 86(1), 34-40, (2008)

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Characterization of LGALS3 (galectin-3) as a player in DNA damage response. Carvalho RS, Fernandes VC, Nepomuceno TC, et al. Cancer Biol. Ther. 15(7), 840-50, (2014)

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Anesthetic propofol reduces endotoxic inflammation by inhibiting reactive oxygen species-regulated Akt/IKKβ/NF-κB signaling. Chung-Hsi Hsing et al PLoS ONE 6, e17598, (2011)

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Selective induction of cell death in melanoma cell lines through targeting of Mcl-1 and A1. Senft D PLoS ONE 7(1), e30821, (2012)

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The rapid decrease in astrocyte-associated dystroglycan expression by focal cerebral ischemia is protease-dependent. Milner R J. Cereb. Blood Flow Metab. 28(4), 812-23, (2008)

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Detection of viable Escherichia coli O157:H7 in ground beef by propidium monoazide real-time PCR. Liu Y and Mustapha A Int. J. Food Microbiol. 170, 48-54, (2014)

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Chitin modulates innate immune responses of keratinocytes. Koller B, Müller-Wiefel AS, Rupec R, et al. PLoS ONE 6(2), e16594, (2011)

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Dichloroacetate induces apoptosis and cell-cycle arrest in colorectal cancer cells. Madhok BM Br. J. Cancer 102(12), 1746-52, (2010)

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The depletion of nuclear glutathione impairs cell proliferation in 3t3 fibroblasts. Markovic J PLoS ONE 4(7), e6413, (2009)

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Hydrogen peroxide acts on sensitive mitochondrial proteins to induce death of a fungal pathogen revealed by proteomic analysis. Guozheng Qin et al PLoS ONE 6, e21945, (2011)

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Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway. Pais TF J. Neuroinflammation 5, 43, (2008)

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Porcine embryos produced after intracytoplasmic sperm injection using xenogeneic pig sperm from neonatal testis tissue grafted in mice. Honaramooz A Reprod. Fertil. Dev. 20(7), 802-7, (2008)

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Conservation and diversity of seed associated endophytes in Zea across boundaries of evolution, ethnography and ecology. Johnston-Monje D PLoS ONE 6(6), e20396, (2011)

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The development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity. Ali S Cancer Res. 69(15), 6208-15, (2009)

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Involvement of enniatins-induced cytotoxicity in human HepG2 cells. Juan-García A, Manyes L, Ruiz MJ, et al. Toxicol. Lett. 218(2), 166-73, (2013)

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CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling. Strauss G J. Exp. Med. 206(6), 1379-93, (2009)

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Toxicological analysis of low-nicotine and nicotine-free cigarettes. Jinguo Chen et al Toxicology 249, 194-203, (2008)

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Microenvironmental influence on pre-clinical activity of polo-like kinase inhibition in multiple myeloma: implications for clinical translation. McMillin DW PLoS ONE 6(7), e20226, (2011)

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The HDAC inhibitor, MPT0E028, enhances erlotinib-induced cell death in EGFR-TKI-resistant NSCLC cells. Chen MC, Chen CH, Wang JC, et al. Cell Death Dis. 4, e810, (2013)

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Retinoic acid-treated pluripotent stem cells undergoing neurogenesis present increased aneuploidy and micronuclei formation. Sartore, RC PLoS ONE 6(6), e20667, (2011)

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SOX2-RNAi attenuates S-phase entry and induces RhoA-dependent switch to protease-independent amoeboid migration in human glioma cells. Oppel F, Müller N, Schackert G, et al. Mol. Cancer 10, 137, (2011)

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Conformational targeting of fibrillar polyglutamine proteins in live cells escalates aggregation and cytotoxicity. Kvam, E PLoS ONE 4(5), e5727, (2009)

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Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. Osorio KM, Lilja KC, and Tumbar T J. Cell Biol. 193(1), 235-50, (2011)

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GX15-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy. Heidari N Cell Death Dis. 1, e76, (2010)

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Perforin rapidly induces plasma membrane phospholipid flip-flop. Sunil S. Metkar et al PLoS ONE 6, e24286, (2011)

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Use of propidium monoazide and increased amplicon length reduce false-positive signals in quantitative PCR for bioburden analysis. Schnetzinger F, Pan Y, and Nocker A Appl. Microbiol. Biotechnol. 97(5), 2153-62, (2013)

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Quantitative detection of viable Bifidobacterium bifidum BF-1 cells in human feces by using propidium monoazide and strain-specific primers. Fujimoto J and Watanabe K Appl. Environ. Microbiol. 79(7), 2182-8, (2013)

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Oroxylin A reverses P-glycoprotein-mediated multidrug resistance of MCF7/ADR cells by G2/M arrest. Zhu L, Zhao L, Wang H, et al. Toxicol. Lett. 219(2), 107-15, (2013)

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Sequencing of type I insulin-like growth factor receptor inhibition affects chemotherapy response in vitro and in vivo. Zeng X Clin. Cancer Res. 15(8), 2840-9, (2009)

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The detection of viable vegetative cells of Bacillus sporothermodurans using propidium monoazide with semi-nested PCR. Cattani F, Ferreira CA, and Oliveira SD Food Microbiol. 34(1), 196-201, (2013)

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Development of PMA real-time PCR method to quantify viable cells of Pantoea agglomerans CPA-2, an antagonist to control the major postharvest diseases on oranges. Soto-Muñoz L, Teixidó N, Usall J, et al. Int. J. Food Microbiol. 180, 49-55, (2014)

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The death domain kinase RIP1 links the immunoregulatory CD40 receptor to apoptotic signaling in carcinomas. Knox PG, Davies CC, Ioannou M, et al. J. Cell Biol. 192(3), 391-9, (2011)

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Effects of antithrombotic drugs fondaparinux and tinzaparin on in vitro proliferation and osteogenic and chondrogenic differentiation of bone-derived mesenchymal stem cells. Papathanasopoulos A J. Orthop. Res. 29(9), 1327-35, (2011)

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The p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage. Tu HC Proc. Natl. Acad. Sci. U. S. A. 106(4), 1093-8, (2009)

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14-3-3sigma gene silencing during melanoma progression and its role in cell cycle control and cellular senescence. Schultz J Mol. Cancer 8, 53, (2009)

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Epstein-Barr virus-encoded microRNA BART15-3p promotes cell apoptosis partially by targeting BRUCE. Choi H, Lee H, Kim SR, et al. J. Virol. 87(14), 8135-44, (2013)

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Lapatinib induces autophagy, apoptosis and megakaryocytic differentiation in chronic myelogenous leukemia K562 cells. Huang HL, Chen YC, Huang YC, et al. PLoS ONE 6(12), e29014, (2011)

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Human DNA polymerase β polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity. Zhigang Guo et al Nucleic Acids Res. 37, 3431-41, (2009)

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Apoptotic cells induce dendritic cell-mediated suppression via interferon-γ-induced IDO. Charlotte A Williams et al Immunology 124, 89-101, (2008)

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Discrimination of infectious hepatitis A viruses by propidium monoazide real-time RT-PCR. Sánchez G, Elizaquível P, and Aznar R Food Environ. Virol. 4(1), 21-5, (2012)

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Preparation and characterization of realgar nanoparticles and their inhibitory effect on rat glioma cells. An YL, Nie F, Wang ZY, et al. Int. J. Nanomedicine 6, 3187-94, (2011)

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Sequential transcription factor targeting for diffuse large B-cell lymphomas. Cerchietti LC Cancer Res. 68(9), 3361-9, (2008)

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Akt regulates centrosome migration and spindle orientation in the early Drosophila melanogaster embryo. Graham J. Buttrick et al J. Cell Biol. 180, 537-48, (2008)

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Oxymatrine induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome c. Ling Q, Xu X, Wei X, et al. J. Exp. Clin. Cancer Res 30, 66, (2011)

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Cell Density-dependent Inhibition Of Epidermal Growth Factor Receptor Signaling By P38alpha Mitogen-activated Protein Kinase Via Sprouty2 Downregulation. Swat, A., et al. Mol. Cell. Endocrinol. 29, 3332-43, (2009)

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Improving efficiency of viability-PCR for selective detection of live cells. Nkuipou-Kenfack E, Engel H, Fakih S, et al. J. Microbiol. Methods 93(1), 20-4, (2013)

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Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts. Gediya, L.K., et al. Bioorg. Med. Chem. 16, 3352-3360, (2008)

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HIV-1 and recombinant gp120 affect the survival and differentiation of human vessel wall-derived mesenchymal stem cells. Gibellini D Retrovirology 8, 40, (2011)

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Small compound 6-O-angeloylplenolin induces mitotic arrest and exhibits therapeutic potentials in multiple myeloma. Ying Liu et al PLoS ONE 6, e21930, (2011)

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Alkenyl group is responsible for the disruption of microtubule network formation in human colon cancer cell line HT-29 cells. Hosono T Carcinogenesis 29(7), 1400-6, (2008)

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The antidiabetic drug ciglitazone induces high grade bladder cancer cells apoptosis through the up-regulation of TRAIL. Plissonnier ML, Fauconnet S, Bittard H, et al. PLoS ONE 6(12), e28354, (2011)

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Aspergillus fumigatus RasA regulates asexual development and cell wall integrity. Fortwendel JR Eukaryotic Cell 7(9), 1530-9, (2008)

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Inhibition of Toxoplasma gondii growth by pyrrolidine dithiocarbamate is cell cycle specific and leads to population synchronization. Magnolia M. Conde de Felipe et al Mol. Biochem. Parasitol. 157, 22-31, (2008)

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Premature chromosome condensation induced by caffeine, 2-aminopurine, staurosporine and sodium metavanadate in S-phase arrested HeLa cells is associated with a decrease in Chk1 phosphorylation, formation of phospho-H2AX and minor cytoskeletal rearrangements. Rybaczek D Histochem. Cell Biol. 135(3), 263-80, (2011)

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DNA damage mediated s and g(2) checkpoints in human embryonal carcinoma cells. Wang X Stem Cells 27(3), 568-76, (2009)

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Pharmacological inhibition of PAR2 with the pepducin P2pal-18S protects mice against acute experimental biliary pancreatitis. Michael ES, Kuliopulos A, Covic L, et al. Am. J. Physiol. Gastrointest. Liver Physiol. 304(5), G516-26, (2013)

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BNP signaling is crucial for embryonic stem cell proliferation. Abdelalim EM PLoS ONE 4(4), e5341, (2009)

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Prostaglandin F2alpha promotes muscle cell survival and growth through upregulation of the inhibitor of apoptosis protein BRUCE. Jansen KM Cell Death Differ. 15(10), 1619-28, (2008)

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Role of adaptive and non-adaptive mechanisms forming complex patterns of genome size variation in six cytotypes of polyploid Allium oleraceum (Amaryllidaceae) on a continental scale. Duchoslav M, Šafářová L, and Jandová M Ann. Bot. 111(3), 419-31, (2013)

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Induction of eosinophil apoptosis by the cyclin-dependent kinase inhibitor AT7519 promotes the resolution of eosinophil-dominant allergic inflammation. Alessandri AL PLoS ONE 6(9), e25683, (2011)

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A novel in vitro sperm head decondensation protocol for rapid flow cytometric measurement of deoxyribonucleic acid content. Antonucci N, Manes S, Corradetti B, et al. Fertil. Steril. 99(7), 1857-61, (2013)

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Differential neuronal expression of receptor interacting protein 3 in rat retina: involvement in ischemic stress response. Huang JF, Shang L, Zhang MQ, et al. BMC Neurosci. 14, 16, (2013)

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Degenerate wave and capacitive coupling increase human MSC invasion and proliferation while reducing cytotoxicity in an in vitro wound healing model. Michelle Griffin et al PLoS ONE 6, e23404, (2011)

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Overexpression of UbcH10 alternates the cell cycle profile and accelerate the tumor proliferation in colon cancer. Fujita, T BMC Cancer 9, 87, (2009)

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Scutellaria barbate extract induces apoptosis of hepatoma H22 cells via the mitochondrial pathway involving caspase-3. Zhi-Jun Dai et al World J. Gastroenterol. 14, 7321-8, (2008)

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Neisseria gonorrhoeae infection protects human endocervical epithelial cells from apoptosis via expression of host antiapoptotic proteins. S. A. Follows et al Infect. Immun. 77, 3602-10, (2009)

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Loss of Tbx2 delays optic vesicle invagination leading to small optic cups. Behesti H Dev. Biol. 333(2), 360-72, (2009)

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Downregulation of heat shock protein 70 protects rheumatoid arthritis fibroblast-like synoviocytes from nitric oxide-induced apoptosis. Kang EH Arthritis. Res. Ther. 11(4), R130, (2009)

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Adeno-associated virus type 2 infection activates caspase dependent and independent apoptosis in multiple breast cancer lines but not in normal mammary epithelial cells. Samina Alam et al Mol. Cancer 10, 97, (2011)

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Plant geminivirus rep protein induces rereplication in fission yeast. Kittelmann K J. Virol. 83(13), 6769-78, (2009)

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Comparative analysis of oncogenic properties and nuclear factor-kappaB activity of latent membrane protein 1 natural variants from Hodgkin's lymphoma's Reed-Sternberg cells and normal B-lymphocytes. Nathalie Faumont et al Haematologica 94, 355-63, (2009)

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The UL15 protein of herpes simplex virus type 1 is necessary for the localization of the UL28 and UL33 proteins to viral DNA replication centres. Martin R. Higgs et al J. Gen. Virol. 89, 1709-15, (2008)

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Manipulating cell adhesions with optical tweezers for study of cell-to-cell interactions. Hu S, Gou X, Han H, et al. J. Biomed. Nanotechnol. 9(2), 281-5, (2013)

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Quantification of propidium iodide delivery using millisecond electric pulses: experiments. Sadik MM, Li J, Shan JW, et al. Biochim. Biophys. Acta 1828(4), 1322-8, (2013)

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Analysis of EGFR signaling pathway in nasopharyngeal carcinoma cells by quantitative phosphoproteomics. Ruan L Proteome Sci. 9, 35, (2011)

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Overexpression of Insig-1 protects β cell against glucolipotoxicity via SREBP-1c. Chen K J. Biomed. Sci. 18, 57, (2011)

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Detrimental role of CC chemokine receptor 4 in murine polymicrobial sepsis. Tobias Traeger et al Infect. Immun. 76, 5285-93, (2008)

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Induction of BAG2 protein during proteasome inhibitor-induced apoptosis in thyroid carcinoma cells. Wang HQ, Zhang HY, Hao FJ, et al. Br. J. Pharmacol. 155(5), 655-60, (2008)

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Turnover of BRCA1 involves in radiation-induced apoptosis. Weijun Liu et al PLoS ONE 5, e14484, (2010)

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Detection of viable but nonculturable Escherichia coli O157:H7 using propidium monoazide treatments and qPCR. Xiao XL, Tian C, Yu YG, et al. Can. J. Microbiol. 59(3), 157-63, (2013)

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Zinc oxide nanoparticles as selective killers of proliferating cells. Taccola L Int. J. Nanomedicine 6, 1129-40, (2011)

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Small molecule screening reveals a transcription-independent pro-survival function of androgen receptor in castration-resistant prostate cancer. Natalia V. Narizhneva et al Cell Cycle 8, 4155-67, (2010)

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Pax6 is essential for the maintenance and multi-lineage differentiation of neural stem cells, and for neuronal incorporation into the adult olfactory bulb. Curto GG, Nieto-Estévez V, Hurtado-Chong A, et al. Stem Cells Dev. 23(23), 2813-30, (2014)

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Inhibitory effect of IL-17 on neural stem cell proliferation and neural cell differentiation. Li Z, Li K, Zhu L, et al. BMC Immunol. 14, 20, (2013)

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Deletion of the protein kinase A regulatory subunit leads to deregulation of mitochondrial activation and nuclear duplication in Aspergillus fumigatus. Fuller KK Eukaryotic Cell 8(3), 271-7, (2009)

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Small molecule screening with laser cytometry can be used to identify pro-survival molecules in human embryonic stem cells. Sherman SP and Pyle AD PLoS ONE 8(1), e54948, (2013)

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Antibacterial activity and mechanism of action of ε-poly-L-lysine. Ye R, Xu H, Wan C, et al. Biochem. Biophys. Res. Commun. 439(1), 148-53, (2013)

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Gain in toxic function of stefin B EPM1 mutants aggregates: correlation between cell death, aggregate number/size and oxidative stress. Polajnar M, Zavašnik-Bergant T, Kopitar-Jerala N, et al. Biochim. Biophys. Acta 1843(9), 2089-99, (2014)

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Human dendritic cells infected with an adenoviral vector suppress proliferation of autologous and allogeneic T cells. Newton KR Immunology 125(4), 469-79, (2008)

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Quantification of viable Giardia cysts and Cryptosporidium oocysts in wastewater using propidium monoazide quantitative real-time PCR. Alonso JL, Amorós I, and Guy RA Parasitol. Res. 113(7), 2671-8, (2014)

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Constitutive expression of Bcl-2 in the haematopoietic compartment alters the metabolism of iron and increases resistance to mycobacterial infection. Flórido M Clin. Exp. Immunol. 156(1), 61-8, (2009)

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Molecular monitoring of Escherichia coli O157: H7 sterilization rate using qPCR and propidium monoazide treatment. Xing-Long X, Cong-Cong L, Yang Q, et al. Lett. Appl. Microbiol. 56(5), 333-9, (2013)

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Increased expression of AGS3 in rat brain cortex after traumatic brain injury. Wang W, Li Q, Zou F, et al. J. Neurosci. Res. 91(5), 726-36, (2013)

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Moderate and severe malnutrition alters proliferation of spleen cells in rats. Cortés-Barberena E, Ceballos-Olvera I, González-Márquez H, et al. Cell Prolif. 46(2), 164-71, (2013)

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Structure-activity relationships and the cytotoxic effects of novel diterpenoid alkaloid derivatives against A549 human lung carcinoma cells. Koji Wada et al J. Nat. Med. 65, 43-9, (2010)

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Multiplex polymerase chain reaction using ethidium monoazide and propidium monoazide for distinguishing viable and dead cells of arcobacters in biofilm. Hrušková L, Mot'ková P, and Vytřasová J Can. J. Microbiol. 59(12), 797-802, (2013)

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Dual-color high-resolution fiber-FISH analysis on lethal white syndrome carriers in sheep. Pauciullo A, Fleck K, Lühken G, et al. Cytogenet. Genome Res. 140(1), 46-54, (2013)

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Recombinant β-1,3-1,4-glucanase from Theobroma cacao impairs Moniliophthora perniciosa mycelial growth. Britto DS, Pirovani CP, Andrade BS, et al. Mol. Biol. Rep. 40(9), 5417-27, (2013)

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Beil. 22,IV,5519

Corp MSDS 1 (2), 2955:C / FT-IR 2 (3), 3935:D / RegBook 1 (2), 2635:B / Sigma FT-IR 1 (2), 859:B / Structure Index 1, 415:A:5

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