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Substituted indoles and purines have frequently been referred to as “privileged structures” since they are capable of binding to multiple receptors with high affinity, and thus have applications acro...
Keywords: Building blocks, Medicinal chemistry
30-yr course and favorable outcome of alveolar echinococcosis despite multiple metastatic organ involvement in a non-immune suppressed patient. Bardonnet K, Vuitton DA, Grenouillet F, et al. Ann. Clin. Microbiol. Antimicrob. 12, 1, (2013)
Assessment of a school-based mass treatment for soil-transmitted helminth infections in Capiz, the Philippines. Bacon KM, Shah M, Taylor L, et al. Southeast Asian J. Trop. Med. Public Health 43(3), 589-600, (2012)
Nematodicidal activity of flubendazole and its reduced metabolite on a murine model of Trichinella spiralis infection. Urbizu L, Confalonieri A, Sánchez Bruni S, et al. Chemotherapy 58(4), 295-8, (2012)
Comparison of single and split-dose flubendazole treatment for the nematode parasite Trichostrongylus tenuis in experimentally infected grey partridges Perdix perdix. Purdy D, Aebischer NJ, and Davis C Parasitology 139(13), 1780-3, (2012)
Current status of the efficacy and effectiveness of albendazole and mebendazole for the treatment of Ascaris lumbricoides in North-Western Indonesia. Lubis IN, Pasaribu S, and Lubis CP Asian Pac. J. Trop. Med. 5(8), 605-9, (2012)
Determinants of maternal health services utilization in urban settings of the Democratic Republic of Congo--a case study of Lubumbashi City. Abel Ntambue ML, Françoise Malonga K, Dramaix-Wilmet M, et al. BMC Pregnancy Childbirth 12, 66, (2012)
The metabolism of flubendazole and the activities of selected biotransformation enzymes in Haemonchus contortus strains susceptible and resistant to anthelmintics. Vokřál I, Bártíková H, Prchal L, et al. Parasitology 139(10), 1309-16, (2012)
Synthesis and anthelmintic activity of 7-substituted 3,4a-dimethyl-4a,5a,8a,8b-tetrahydro-6H-pyrrolo[3',4':4,5]furo[3,2-b]pyridine-6,8(7H)-diones. Peter Jeschke et al Bioorg. Med. Chem. Lett. 15, 2375-9, (2005)
Metal-mediated inhibition of Escherichia coli methionine aminopeptidase: structure-activity relationships and development of a novel scoring function for metal-ligand interactions. Rolf Schiffmann et al J. Med. Chem. 49, 511-22, (2006)
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