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O0380 Fluka

Oxymetholone

analytical standard

Synonym: 17β-Hydroxy-2-(hydroxymethylene)-17-methyl-5α-androstan-3-one, Anasterone

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Properties

Related Categories Additional Standards, All Doping Standards (A-Z), Anabolic Steroid, Analytical Standards, Analytical/Chromatography,
grade   analytical standard
assay   ≥95%
form   neat
  solid
drug control   USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
color   white to light yellow
solubility   H2O: ≤0.5 mg/mL
  ethanol: soluble6.7 mg/mL
format   neat
storage temp.   2-8°C

Description

Biochem/physiol Actions

Androgen

Price and Availability

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Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Warning
Hazard statements 
Precautionary statements 
Hazard Codes (Europe) 
T
Risk Statements (Europe) 
Safety Statements (Europe) 
53-22-26-36/37/39
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Peer-Reviewed Papers

References

Set your institution to view full text papers.

Oxymetholone. Rep. Carcinog. 12, 338-40, (2011)

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Acute myocardial infarction and renal infarction in a bodybuilder using anabolic steroids. Ilhan E, Demirci D, Güvenç TS, et al. Turk. Kardiyol. Dern. Ars. 38(4), 275-8, (2010)

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[Bone marrow failure due to telomere associated gene mutation]. Yamaguchi H and Dan K Rinsho. Ketsueki. 51(8), 646-53, (2010)

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Oxymetholone. Rep. Carcinog. 10, 191-2, (2002)

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Testosterone replacement for hypogonadism: clinical findings and best practices. Hengge UR AIDS Read. 13(12 Suppl), S15-21, (2003)

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Hepatocellular adenomas associated with anabolic androgenic steroid abuse in bodybuilders: a report of two cases and a review of the literature. Socas L, Zumbado M, Pérez-Luzardo O, et al. Br. J. Sports Med. 39(5), e27, (2005)

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Effect of oral anabolic steroid on muscle strength and muscle growth in hemodialysis patients. Supasyndh O, Satirapoj B, Aramwit P, et al. Clin. J. Am. Soc. Nephrol. 8(2), 271-9, (2013)

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Androgens and liver tumors: Fanconi's anemia and non-Fanconi's conditions. Velazquez I and Alter BP Am. J. Hematol. 77(3), 257-67, (2004)

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Hereditary angioedema: a current state-of-the-art review, V: attenuated androgens for the treatment of hereditary angioedema. Banerji A, Sloane DE, and Sheffer AL Ann. Allergy Asthma Immunol. 100(1 Suppl 2), S19-22, (2008)

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Mass spectrometric description of novel oxymetholone and desoxymethyltestosterone metabolites identified in human urine and their importance for doping control. Sobolevsky T and Rodchenkov G Drug Test. Anal. 4(9), 682-91, (2012)

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Review of oxymetholone: a 17alpha-alkylated anabolic-androgenic steroid. Pavlatos AM, Fultz O, Monberg MJ, et al. Clin. Ther. 23(6), 789-801; discussion 771, (2001)

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Association of advanced chronic progressive nephropathy (CPN) with renal tubule tumors and precursor hyperplasia in control F344 rats from two-year carcinogenicity studies. Hard GC, Betz LJ, and Seely JC Toxicol. Pathol. 40(3), 473-81, (2012)

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Intracerebroventricular self-administration of commonly abused anabolic-androgenic steroids in male hamsters (Mesocricetus auratus): nandrolone, drostanolone, oxymetholone, and stanozolol. Ballard CL and Wood RI Behav. Neurosci. 119(3), 752-8, (2005)

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Oxymetholone hepatotoxicity enhanced by concomitant use of cyclosporin A in a bone marrow transplant patient. Wood P and Yin JA Clin. Lab. Haematol. 16(2), 201-4, (1994)

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Detection of urinary metabolites common to structurally related 17alpha-alkyl anabolic steroids in horses and application to doping tests in racehorses: methandienone, methandriol, and oxymetholone. Yamada M, Aramaki S, Kurosawa M, et al. J. Anal. Toxicol. 32(5), 387-91, (2008)

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Characterization of spontaneous and chemically induced cardiac lesions in rodent model systems: the national toxicology program experience. Jokinen MP, Lieuallen WG, Johnson CL, et al. Cardiovasc. Toxicol. 5(2), 227-44, (2005)

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Direct and indirect effects of androgens on survival of hematopoietic progenitor cells in vitro. Kim SW, Hwang JH, Cheon JM, et al. J. Korean Med. Sci. 20(3), 409-16, (2005)

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Morphologic aspects of rodent cardiotoxicity in a retrospective evaluation of National Toxicology Program studies. Jokinen MP, Lieuallen WG, Boyle MC, et al. Toxicol. Pathol. 39(5), 850-60, (2011)

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Oral oxymetholone reduces mortality induced by gamma irradiation in mice through stimulation of hematopoietic cells. Hosseinimehr SJ, Zakaryaee V, and Froughizadeh M Mol. Cell Biochem. 287(1-2), 193-9, (2006)

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Improvement in erythropoieis-stimulating agent-induced pure red-cell aplasia by introduction of darbepoetin-α when the anti-erythropoietin antibody titer declines spontaneously. Lee H, Yang J, Kim H, et al. J. Korean Med. Sci. 25(11), 1676-9, (2010)

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Clinical course of non-severe aplastic anemia in adults. Kwon JH, Kim I, Lee YG, et al. Int. J. Hematol. 91(5), 770-5, (2010)

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The efficacy of oxymetholone in combination with erythropoietin on hematologic parameters and muscle mass in CAPD patients. Aramwit P, Palapinyo S, Wiwatniwong S, et al. Int. J. Clin. Pharmacol. Ther. 48(12), 803-13, (2010)

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Clonal monosomy 7 in a megakaryoblastic leukemia developed on the basis of Fanconi anemia. Yilmaz Z, Alioğlu B, Ozalp O, et al. J. Pediatr. Hematol. Oncol. 27(10), 565-6, (2005)

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Oxymetholone ameliorates insulin sensitivity in maintenance hemodialysis patients: a randomized controlled trial. Aramwit P, Kobpipat N, Satirapoj B, et al. Clin. Nephrol. 71(4), 413-22, (2009)

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[Decrease of high density lipoproteins secondary to treatment with anabolizing steroids]. Mañas García MD, Marchán Carranza E, and Galiana Gómez del Pulgar J Rev. Clin. Esp. 207(7), 376-7, (2007)

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[Peliosis hepatitis secondary to hormone treatment]. Tallón García M, Cobelas Cobelas MC, Fernández Sanmartín M, et al. An. Pediatr. (Barc.) 75(4), 286-8, (2011)

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Splenic peliosis and rupture in patients with dyskeratosis congenita on androgens and granulocyte colony-stimulating factor. Giri N, Pitel PA, Green D, et al. Br. J. Haematol. 138(6), 815-7, (2007)

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Merck 14,6967

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