8.20877 EMD Millipore


(-)-Nicotine for synthesis. CAS 54-11-5, pH 10.2 (8.1 g/l, H₂O, 20 °C)., for synthesis

Synonym: 3-(1-Methyl-2-pyrrolidinyl)pyridine, (S)-(-)-Nicotine

  • CAS Number 54-11-5

  • Linear Formula C₁₀H₁₄N₂

  • Molecular Weight 162.23 g/mol

  •  EC Number 200-193-3



Related Categories Biochemicals and Reagents More...
packaging   1 l in Glass btl. pl.coat. (8208771000)
  25 ml in Glass bottle (8208770025)
bp   248.8 °C (1013 hPa)
expl. lim.     0.7 - 4 %(V)
vapor pressure   0.06 hPa (20 °C)
density   1.01 g/cm3 (20 °C)
flash point   111 °C
autoignition temp.   240 °C
mp   -79 °C
pH   10.2 (8.1 g/l, H₂O, 20 °C)
LD 50 oral   LD50 Rat 50 mg/kg
LD 50 dermal   LD50 Rabbit 50 mg/kg
shipped in   ambient
storage temp.   Store below +30°C.
specifications   Assay (GC, area%): ≥ 99.0 % (a/a)
  Density (d 20 °C/ 4 °C): 1.009 - 1.012
  Enantiomeric purity: ≥ 99.0 % (a/a)
  Identity (IR): passes test

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Safety Information

HS Code 
2939 80 00
Hazard Statement(s) 
H301: Toxic if swallowed.
H310: Fatal in contact with skin.
H410: Very toxic to aquatic life with long lasting effects.
Precautionary Statement(s) 
P273: Avoid release to the environment.
P280: Wear protective gloves/ protective clothing.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P308 + P310: IF exposed or concerned: immediately call a POISON CENTER or doctor/ physician.
Storage class 
6.1A Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK 3 highly water endangering
Carcinogenic compounds and flammable compounds labelled "Highly toxic" or "Toxic": container F. Alkyl sulfates are carcinogenic; Take particular care to avoid inhalation and skin contact. To neutralize alkyl sulfates, add dropwise (from a dropping funnel) to concentrated ice-cool Ammonia solution (Cat.No. 105426) with vigorous stirring. Before placing in container D, check the pH with pH Universal indicator strips (Cat.No. 109535).
Hazard Pictogram(s) 
GHS06  GHS06
Hazard Pictogram(s) 
GHS09  GHS09
Hazard Symbols 
Dangerous for the environment  Dangerous for the environment
Hazard Symbols 
Very toxic  Very toxic
Declaration (railroad and road) ADR, RID 
UN 1654 , 6.1, II
Declaration (transport by air) IATA-DGR 
UN 1654 , 6.1, II
Declaration (transport by sea) IMDG-Code 
UN 1654 , 6.1, II
Categories of danger 
very toxic, dangerous for the environment
R Phrase 
R 25-27-51/53
Toxic if swallowed.Very toxic in contact with skin.Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
S Phrase 
S 36/37-45-61
Wear suitable protective clothing and gloves.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).Avoid release to the environment. Refer to special instructions/ Safety data sheets.
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