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  • 8.40102 - 3-Chloro-4-methyl-phenyl isocyanate

8.40102 EMD Millipore

3-Chloro-4-methyl-phenyl isocyanate

3-Chloro-4-methyl-phenyl isocyanate for synthesis. CAS 28479-22-3, molar mass 167.59 g/mol., for synthesis

Synonym: 3-Chloro-p-tolyl isocyanate

  • CAS Number 28479-22-3

  • Linear Formula C₈H₆ClNO

  • Molecular Weight 167.59 g/mol

  •  EC Number 249-050-7



Related Categories Biochemicals and Reagents More...
packaging   10 g in Glass bottle (8401020010)
vapor pressure   0.2 hPa (20 °C)
density   1.229 g/cm3 (20 °C)
flash point   110 °C DIN 51758
autoignition temp.   635 °C DIN 51794
mp   23.5 °C
saturation concentration (air)   1.39 mg/l (20 °C)
LD 50 oral   LD50 Rat > 5000 mg/kg
shipped in   ambient
storage temp.   Store below +30°C.
specifications   Assay (GC, area%): ≥ 95.0 % (a/a)
  Identity (IR): passes test
  Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

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Safety Information

HS Code 
2929 10 00
Hazard Statement(s) 
H314: Causes severe skin burns and eye damage.
H330: Fatal if inhaled.
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H412: Harmful to aquatic life with long lasting effects.
Precautionary Statement(s) 
P273: Avoid release to the environment.
P280: Wear protective gloves/ protective clothing/ eye protection/ face protection.
P301 + P330 + P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P342 + P311: If experiencing respiratory symptoms: Call a POISON CENTER/doctor.
P308 + P310: IF exposed or concerned: immediately call a POISON CENTER or doctor/ physician.
Storage class 
6.1A Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK 1 slightly water endangering
Organic acid halides, anhydrides and isocyanates can be added dropwise to an excess of methanol (Cat. No. 822283) to convert them into the corresponding methyl esters or methyl carbamates. If necessary, neutralize with sodium hydroxide solution (Cat. No. 105587). Fill into container A.
Hazard Pictogram(s) 
GHS05  GHS05
Hazard Pictogram(s) 
GHS06  GHS06
Hazard Pictogram(s) 
GHS08  GHS08
Hazard Symbols 
Very toxic  Very toxic
Declaration (railroad and road) ADR, RID 
UN 3428 , 6.1, II
Declaration (transport by air) IATA-DGR 
UN 3428 , 6.1, II
Declaration (transport by sea) IMDG-Code 
UN 3428 , 6.1, II
Categories of danger 
very toxic, corrosive, sensitizing, dangerous for the environment
R Phrase 
R 26-34-42-52/53
Very toxic by inhalation.Causes burns.May cause sensitisation by inhalation.Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
S Phrase 
S 26-28-36/37/39-45-61
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.After contact with skin, wash immediately with plenty of soap and water.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).Avoid release to the environment. Refer to special instructions/ Safety data sheets.
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