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8.51013 EMD Millipore

HATU

HATU Novabiochem®. CAS 148893-10-1, molar mass 380.23 g/mol., Novabiochem®

  • CAS Number 148893-10-1

  • Linear Formula C₁₀H₁₅N₆O * F₆P

  • Molecular Weight 380.23 g/mol

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Properties

brand family   Novabiochem
packaging   100 g in Plastic bottle (8510130100)
  25 g in Plastic bottle (8510130025)
mp   186 °C decomposes
shipped in   ambient
storage temp.   Store at +2°C to +8°C.

Description

Background information

A highly efficient coupling reagent for solid and solution phase peptide synthesis. In comparative studies HATU has been found to give better coupling yields with less enantiomerization that HBTU, TBTU or PyBOP® [1-3]. It is particularly effective at coupling to N-alkyl amines where other coupling reagents give poor yields and is the preferred reagent for loading resins bearing secondary amino groups.

The product number for this product was previously 01-62-0041.

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Safety & Documentation

Safety Information

HS Code 
2933 99 80
Hazard Statement(s) 
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H317: May cause an allergic skin reaction.
Precautionary Statement(s) 
P280: Wear protective gloves.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304 + P341: IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342 + P311: If experiencing respiratory symptoms: Call a POISON CENTER/doctor.
Storage class 
4.1A Other explosive hazardous materials
WGK 
WGK 3 highly water endangering
Hazard Pictogram(s) 
GHS08  GHS08
Hazard Symbols 
Harmful  Harmful
Categories of danger 
sensitizing
R Phrase 
R 42/43
May cause sensitisation by inhalation and skin contact.
S Phrase 
S 22-36/37-45
Do not breathe dust.Wear suitable protective clothing and gloves.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Protocols & Articles

Articles

Peptide Coupling Reagents Selection Guide

The Novabiochem® brand offers one of the most extensive ranges of high-quality coupling reagents for in situ activation on the market. However, with such a plethora of reagents available, the choice ...
Keywords: Condensations, Coupling reactions, Cyclizations, Racemizations, Solid phase peptide synthesis

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