8.51091 EMD Millipore


DEPBT 3-(Diethoxy-phosphoryloxy)-1,2,3-benzo[d]triazin-4(3H)-one Novabiochem®. CAS 165534-43-0, molar mass 299.22 g/mol., 3-(Diethoxy-phosphoryloxy)-1,2,3-benzo[d]triazin-4(3H)-one Novabiochem®

Synonym: 3-(Diethoxy-phosphoryloxy)-1,2,3-benzo[d]triazin-4(3H)-one,Diethyl-(4-oxo-3H-1,2,3-benzotriazin-3-yl)phosphate

  • CAS Number 165534-43-0

  • Linear Formula C₁₁H₁₄N₃O₅P

  • Molecular Weight 299.22 g/mol



brand family   Novabiochem
packaging   100 g in Plastic bottle (8510910100)
  25 g in Plastic bottle (8510910025)
mp   72 - 75 °C
shipped in   ambient
storage temp.   Store at +2°C to +8°C.
specifications   Colour (visual): white to slight yellow to beige
  Appearance of substance (visual): powder
  Identity (IR): passes test
  Assay (HPLC, area%): ≥ 98.0 % (a/a)


Background information

DEPBT is an in situ coupling reagent that generates racemization resistant Dbht esters [1]. DEPBT has been shown to be highly effective for cyclolactamization of peptides.

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Safety Information

HS Code 
2933 99 80
Hazard Statement(s) 
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary Statement(s) 
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage class 
10 - 13 Other liquids and solids
WGK 3 highly water endangering
Hazard Pictogram(s) 
GHS07  GHS07
Hazard Symbols 
Irritant  Irritant
R Phrase 
R 36/37/38
Irritating to eyes, respiratory system and skin.
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