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8.52035 EMD Millipore

Fmoc-Glu-OtBu

Fmoc-Glu-OtBu Novabiochem®. CAS 84793-07-7, molar mass 425.47 g/mol., Novabiochem®

Synonym: N-α-Fmoc-L-glutamic acid α-t.-butyl ester

  • CAS Number 84793-07-7

  • Linear Formula C₂₄H₂₇NO₆

  • Molecular Weight 425.47 g/mol

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Properties

Related Categories Amino Acids & Derivatives, Chemical Biology, Chemical Synthesis, Glutamic Acid, Peptide Chemistry More...
brand family   Novabiochem
packaging   1 g in Glass bottle (8520350001)
  5 g in Plastic bottle (8520350005)
mp   105 - 110 °C
shipped in   ambient
storage temp.   Store below +30°C.
specifications   Colour (visual): white to slight yellow to beige
  Appearance of substance (visual): powder
  Identity (IR): passes test
  Enantiomeric purity: ≥ 99.5 % (a/a)
  Purity (TLC(011A)): ≥ 98 %
  Purity (TLC(0811)): ≥ 98 %
  Assay (HPLC, area%): ≥ 99.0 % (a/a)
  Solubility (1 mmole in 2 ml DMF): clearly soluble
  Assay (acidimetric): ≥ 95.0 %
  Water (K. F.): ≤ 1.00 %
  For TLC-Systems see our General Catalog

Description

Background information

Selectively protected building block for library synthesis or the preparation of γ-glutamyl peptides. After condensation of the side-chain carboxy with an appropriate amine or alcohol, the α-amino and carboxy functions can be selectively unmasked with 20% piperidine in DMF and 50% TFA in DCM respectively, facilitating the synthesis of branched esters, amides, lactams and lactones containing the glutamyl unit.

The product number for this product was previously 04-12-1075.

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Safety Information

HS Code 
2924 29 70
Storage class 
10 - 13 Other liquids and solids
WGK 
WGK 2 water endangering
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