8.52045 EMD Millipore


Fmoc-Gln(Trt)-OH Novabiochem®. CAS 132327-80-1, molar mass 610.72 g/mol., Novabiochem®

Synonym: N-α-Fmoc-N-γ-trityl-L-glutamine

  • CAS Number 132327-80-1

  • Linear Formula C₃₉H₃₄N₂O₅

  • Molecular Weight 610.72 g/mol



Related Categories Amino Acids & Derivatives, Chemical Biology, Chemical Synthesis, Glutamine, Peptide Chemistry More...
brand family   Novabiochem
packaging   100 g in Plastic bottle (8520450100)
  25 g in Plastic bottle (8520450025)
  250 g in Plastic bottle (8520450250)
mp   110 - 125 °C
shipped in   ambient
storage temp.   Store at -15°C to -25°C.
specifications   Colour (visual): white to off white
  Appearance of substance (visual): powder
  Colour index (0,5 M in DMF): ≤ 150 Hazen
  Identity (IR): passes test
  Enantiomeric purity: ≥ 99.8 % (a/a)
  Purity (HPLC): ≥ 99.0 % (a/a)
  Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
  Fmoc-ß-Ala-Gln (Trt) -OH (HPLC): ≤ 0.1 % (a/a)
  Fmoc-Gln(Trt)-Gln(Trt)-OH (HPLC): ≤ 0.1 % (a/a)
  Fmoc-Gln-OH (HPLC): ≤ 0.1 % (a/a)
  Assay free amino acid (GC): ≤ 0.2 %
  Purity (TLC(011A)): ≥ 98 %
  Purity (TLC(0811)): ≥ 98 %
  Solubility (25 mmole in 50 ml DMF): clearly soluble
  Assay (acidimetric): ≥ 93.0 %
  Water (K. F.): ≤ 2.0 %
  Ethyl acetate (HS-GC): ≤ 0.5 %
  Acetate (IC): ≤ 0.02 %
  For TLC-Systems see our General Catalog


Background information

Fmoc-Gln(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Gln [1]. Coupling can be performed by standard procedures. The trityl-protecting group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp.

The product number for this product was previously 04-12-1090.

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Safety Information

HS Code 
2924 29 70
Storage class 
10 - 13 Other liquids and solids
WGK 2 water endangering
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