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  • 8.52109 - Fmoc-Gly-(Dmb)Gly-OH

8.52109 EMD Millipore


Fmoc-Gly-(Dmb)Gly-OH Novabiochem®. CAS 848861-65-4, molar mass 504.53 g/mol., Novabiochem®

Synonym: N-α-Fmoc-L-glycyl-N-α-(2, 4-dimethoxybenzyl)-glycine

  • CAS Number 848861-65-4

  • Linear Formula C₂₈H₂₈N₂O₇

  • Molecular Weight 504.53 g/mol



Related Categories Amino Acids & Derivatives, Chemical Biology, Chemical Synthesis, Peptide Chemistry
brand family   Novabiochem
packaging   1 g in Glass bottle (8521090001)
  5 g in Glass bottle (8521090005)
shipped in   ambient
storage temp.   Store at +2°C to +8°C.
specifications   Colour (visual): white to slight yellow
  Appearance of substance (visual): powder
  Identity (IR): passes test
  Purity (TLC(0811)): ≥ 98 %
  Assay (HPLC, area%): ≥ 95.0 % (a/a)
  Assay (acidimetric): ≥ 90.0 %
  Water (K. F.): ≤ 2.00 %
  For TLC-Systems see our General Catalog


Background information

The use of this derivative was found to be essential for the synthesis of peptides related to nucleolin [1].

Fmoc-Aaa-(Dmb)Gly-OH dipeptides offer the same benefits as pseudoproline dipeptides but for peptide sequences containing Gly. They are extremely easy to use. Standard coupling methods like PyBOP®/DIPEA or DIPCDI/HOBt can be used for their introduction. Removal of the Dmb group and regeneration of the glycine residue occurs during the course of standard TFA-mediated cleavage reaction.

The product number for this product was previously 04-12-1266.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".

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Safety Information

HS Code 
2924 29 70
Storage class 
10 - 13 Other liquids and solids
WGK 2 water endangering
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